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Tumor Metastasis Is Not Due to Adaptation of Cells to a New Organ Environment

Data up to Jan 2025

Published1982
Citations89
References49

Total Citations Per Year

Abstract

References (49)

The pathogenesis of cancer metastasis

1980 • 1,750 citations

Metastasis Results from Preexisting Variant Cells Within a Malignant Tumor

1977 • 1,422 citations

Selection of Successive Tumour Lines for Metastasis

1973 • 1,360 citations

The Biology of Cancer Invasion and Metastasis

1978 • 819 citations

Biological behavior of malignant melanoma cells correlated to their survival in vivo.

1975 • 586 citations

Normal and Pathologic Anatomy of the Reticular Tissue in Laboratory Mice, With a Classification and Discussion of Neoplasms

1954 • 429 citations

Organ Selectivity for Implantation Survival and Growth of B16 Melanoma Variant Tumor Lines 2

1976 • 297 citations

Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mammary tumor.

1978 • 281 citations

Development and Biologic Properties of Malignant Cell Sublines and Clones of a Spontaneously Metastasizing Rat Mammary Adenocarcinoma<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1982 • 253 citations

Metastatic heterogeneity of cells from an ultraviolet light-induced murine fibrosarcoma of recent origin.

1978 • 248 citations

Specificity of arrest, survival, and growth of selected metastatic variant cell lines.

1978 • 203 citations

Demonstration of multiple phenotypic diversity in a murine melanoma of recent origin.

1981 • 195 citations

Non-metastasising variants selected from metastasising melanoma cells

1977 • 174 citations

Selection and altered properties of brain-colonising metastatic melanoma

1978 • 171 citations

Tumor metastases and cell‐mediated immunity in a model system in DBA/2 mice. I. Tumor invasiveness in vitro and metastasis formation in vivo

1979 • 159 citations

Metastatic behavior of a murine reticulum cell sarcoma exhibiting organ-specific growth.

1981 • 154 citations

Transpulmonary passage of tumor cell emboli.

1952 • 146 citations

Differences in drug sensitivity among tumor cells from parental tumors, selected variants, and spontaneous metastases.

1981 • 140 citations

Selection and Biologic Properties of Malignant Variants of a Murine Lymphosarcoma<xref ref-type="fn" rid="FN2">2</xref>

1978 • 138 citations

Selection and In Vivo Properties of Lectin-Attachment Variants of Malignant Murine Lymphosarcoma Cell Lines<xref ref-type="fn" rid="FN2">2</xref>

1980 • 99 citations

Malignancies of metastatic murine lymphosarcoma cell lines and clones correlate with decreased cell surface display of RNA tumor virus envelope glycoprotein gp70.

1980 • 95 citations

Liver-colonizing melanoma cells selected from B-16 melanoma

1979 • 93 citations

Fate of Recirculating B16 Melanoma Metastatic Variant Cells in Parabiotic Syngeneic Recipients: Brief Communication 2

1977 • 90 citations

Induction of a tumor with greatly increased metastatic growth potential by injection of cells from a low‐metastatic H‐2 heterozygous tumor cell line into an H‐2 incompatible parental strain

1978 • 87 citations

Selection of malignant melanoma variant cell lines for ovary colonization

1979 • 83 citations

Immunologic studies of membrane mutants of a highly metastatic murine tumor.

1979 • 74 citations

Antigenic differences between primary methylcholanthrene‐induced rat sarcomas and post‐surgical recurrences

1977 • 72 citations

Tumor heterogeneity and stability of the metastatic phenotype of mouse KHT sarcoma cells.

1981 • 72 citations

In Vivo Isolation of a Metastatic Tumor Cell Variant Involving Selective and Nonadaptive Processes<xref ref-type="fn" rid="fn2">2</xref>, <xref ref-type="fn" rid="fn3">3</xref>

1981 • 71 citations

THE RELATIONSHIP BETWEEN THE DISSEMINATION OF TUMOR CELLS AND THE DISTRIBUTION OF METASTASES.

1964 • 70 citations

Heterogeneity and variability of artificial lung colony-forming ability among clones from mouse fibrosarcoma.

1978 • 70 citations

Natural Polyclonality of Spontaneous AKR Leukemia and Its Consequences for So-Called Specific Immunotherapy2

1979 • 69 citations

A Timekeeping Enzyme in the Pineal Gland

1979 • 67 citations

The generation of tumor heterogeneity in vivo

1980 • 66 citations

The organ selectivity of experimentally induced metastases in rats

1952 • 64 citations

Antigenic differences among osteogenic sarcoma tumor cells taken from different locations in human tumors.

1977 • 58 citations

Heterogeneity in growth inhibition by beta-trans-retinoic acid of metastatic B16 melanoma clones and in vivo-selected cell variant lines.

1979 • 54 citations

Differential growth of metastatic tumors in liver and lung; experiments with rabbit V2 carcinoma.

1952 • 53 citations

Radiation and Melanoma: Response of B16 Mouse Tumor Cells and Clonal Lines to in Vitro Irradiation

1979 • 49 citations

Stellar Physics: The Brightest Stars . Cornelis de Jager. Reidel, Boston, 1980 (distributor, Kluwer Boston, Hingham, Mass.). xii, 460 pp., illus. Cloth, $73.50; paper, $31.50. Geophysics and Astrophysics Monographs, vol. 19.

1981 • 47 citations

Heterogeneity in hyperthermic sensitivities of rat 13762NF mammary adenocarcinoma cell clones of differing metastatic potentials.

1982 • 43 citations

Selection for virulence and organ‐specific metastasis of herpesvirus‐transformed lymphoma cells

1980 • 40 citations

Experimental Tumor Metastasis: Characteristics and Organ Specificity

1978 • 37 citations

Membrane-associated alterations detected in poorly tumorigenic lectin-resistant variant sublines of a highly malignant and metastatic murine tumor.

1981 • 34 citations

On heterogeneity of non-Hodgkin's lymphomas as regards sensitivity to cytostatic drugs

1980 • 31 citations

Heterogeneity in Hyperthermic Sensitivities of Rat 13762NF Mammary Adenocarcinoma Cell Clones of Differing Metastatic Potentials

1982 • 28 citations

Lipid‐protein interactions in membranes: Effect of lipid composition on mobility of spin‐labeled cysteine residues in yeast plasma membrane

1979 • 13 citations

Contrasts between human and experimental melanomas.

1959 • 9 citations

Deleted Work

1955 • 0 citations

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