Differential down-regulation of protein kinase C selectively affects IgE-dependent exocytosis and inositol trisphosphate formation

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

The Complete Primary Structure of Protein Kinase C—the Major Phorbol Ester Receptor

1986 • 878 citations

Protein kinase C phosphorylates the inhibitory guanine‐nucleotide‐binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase

1985 • 736 citations

Cloning and expression of multiple protein kinase C cDNAs

1986 • 683 citations

The polyphosphoinositide phosphodiesterase of erythrocyte membranes

1981 • 614 citations

Limited Proteolysis of Protein Kinase C Subspecies by Calcium-dependent Neutral Protease (Calpain)

1989 • 470 citations

Down-regulation of protein kinase C is due to an increased rate of degradation

1987 • 442 citations

1-(5-isoquinol inesulfonyl)-2-methylpiperazine (H-7) is a selective inhibitor of protein kinase c in rabbit platelets

1984 • 437 citations

Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2.

1987 • 339 citations

K-252a, a potent inhibitor of protein kinase C from microbial origin.

1986 • 332 citations

Differential Down-regulation of Protein Kinase C Isozymes

1989 • 219 citations

The action of the protein kinase C inhibitor, staurosporine, on human platelets. Evidence against a regulatory role for protein kinase C in the formation of inositol trisphosphate by thrombin

1988 • 218 citations

The calcium signal and phosphatidylinositol breakdown in 2H3 cells.

1984 • 214 citations

Protein kinase C regulation of the receptor-coupled calcium signal in histamine-secreting rat basophilic leukaemia cells

1985 • 186 citations

Synergistic action of protein kinase C and calcium for histamine release from rat peritoneal mast cells

1984 • 179 citations

Purification and characterization of a phosphoinositide-specific phospholipase C from guinea pig uterus. Phosphorylation by protein kinase C in vivo.

1987 • 161 citations

THE PREPARATION AND SOME PROPERTIES OF PURIFIED ANTIBODY SPECIFIC FOR THE 2,4-DINITROPHENYL GROUP

1960 • 151 citations

Multisite phosphorylation of the alpha subunit of transducin by the insulin receptor kinase and protein kinase C.

1986 • 150 citations

Differential down‐regulation of protein kinase C subspecies in KM3 cells

1988 • 115 citations

Rapid microassay for protein kinase C translocation in Swiss 3T3 cells

1986 • 100 citations

Synergistic signals in the mechanism of antigen-induced exocytosis in 2H3 cells: evidence for an unidentified signal required for histamine release.

1987 • 90 citations

Protein kinase C, a coupling element between stimulus and secretion of basophils

1984 • 54 citations

Ca2+-dependent and phorbol ester activating phosphorylation of a 36K-dalton protein of rat basophilic leukemia cell membranes and immunoprecipitation of the phosphorylated protein with IgE-anti IgE system

1984 • 18 citations

Evaluation of the role of inositol trisphosphate in IgE-dependent exocytosis

1990 • 5 citations