Tyrosine phosphorylation of inducible nitric oxide synthase: implications for potential post-translational regulation

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

1990 • 3,304 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1992 • 1,636 citations

Okadaic acid: a new probe for the study of cellular regulation

1990 • 1,396 citations

Activated microglia mediate neuronal cell injury via a nitric oxide mechanism.

1992 • 1,121 citations

Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform.

1992 • 1,004 citations

Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.

1992 • 877 citations

Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide.

1993 • 782 citations

Nitric oxide, a novel biologic messenger

1992 • 754 citations

Comparison of three actin-coding sequences in the mouse; Evolutionary relationships between the actin genes of warm-blooded vertebrates

1986 • 678 citations

Calmodulin is a subunit of nitric oxide synthase from macrophages.

1992 • 640 citations

Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification of flavin and calmodulin binding sites.

1992 • 621 citations

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

1992 • 616 citations

Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells.

1991 • 599 citations

Calcium‐dependent nitric oxide synthesis in endothelial cytosol is mediated by calmodulin

1990 • 507 citations

Phosphorylation and subcellular translocation of endothelial nitric oxide synthase.

1993 • 329 citations

The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma.

1990 • 314 citations

Phosphorylation by calcium calmodulin-dependent protein kinase II and protein kinase C modulates the activity of nitric oxide synthase

1991 • 275 citations

Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages.

1992 • 248 citations

Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccharide-responsive and lipopolysaccharide-nonresponsive murine macrophages.

1993 • 166 citations

Dual mechanism for the control of inducible-type NO synthase gene expression in macrophages during activation by interferon-gamma and bacterial lipopolysaccharide. Transcriptional and post-transcriptional regulation.

1994 • 163 citations

Phosphorylation of nitric oxide synthase by protein kinase A

1991 • 114 citations

The role of protein kinase C in the induction of nitric oxide synthesis by murine macrophages

1992 • 110 citations

Nitric Oxide Synthase Expression in Glial Cells: Suppression by Tyrosine Kinase Inhibitors

1994 • 105 citations

A simple method of obtaining monocytes in suspension

1984 • 93 citations

Activation of tumoricidal properties in macrophages by lipopolysaccharide requires protein-tyrosine kinase activity

1993 • 80 citations

Identification and characterization of a calmodulin-dependent nitric oxide synthase from GH3 pituitary cells

1992 • 64 citations

Both tumor necrosis factor and nitric oxide participate in lysis of simian virus 40-transformed cells by activated macrophages.

1992 • 58 citations

Phospholipase C-gamma 1 is translocated to the membrane of rat basophilic leukemia cells in response to aggregation of IgE receptors.

1992 • 45 citations

Orthovanadate induces translocation of phospholipase C-gamma 1 and -gamma 2 in permeabilized mast cells.

1993 • 23 citations

Neuronal toxicity by macrophages in mixed brain cell culture is augmented by antineuronal IgG and dependent upon nitric oxide synthesis

1993 • 22 citations

A role for tyrosine kinase activation in interleukin-1β induced nitric oxide production in the insulin producing cell line RINm-5F

1994 • 17 citations

Particulate and Soluble Forms of the Inducible Nitric Oxide Synthase Are Distinguishable at the Amino Terminus in Raw 264.7 Macrophage Cells

1995 • 16 citations