Regulation of vascular integrins [published erratum appears in Blood 1994 Apr 1;83(7):2013]

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1984 • 3,580 citations

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.

1985 • 968 citations

Platelet Membrane Glycoprotein IIb/IIIa: Member of a Family of Arg-Gly-Asp—Specific Adhesion Receptors

1986 • 945 citations

Exposure of platelet fibrinogen receptors by ADP and epinephrine.

1979 • 868 citations

The platelet membrane glycoprotein IIb-IIIa complex

1988 • 841 citations

Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin.

1989 • 807 citations

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase.

1992 • 743 citations

Structure and Function of Leukocyte Integrins

1990 • 620 citations

The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets.

1985 • 594 citations

Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion.

1986 • 442 citations

Regulation of the fibronectin receptor affinity by divalent cations.

1988 • 441 citations

Localization of an Arg-Gly-Asp Recognition Site Within an Integrin Adhesion Receptor

1988 • 402 citations

Identification of membrane proteins mediating the interaction of human platelets

1980 • 383 citations

Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in ADP-induced platelet aggregation.

1980 • 373 citations

Structure of the Integrin VLA‐4 and its Cell‐Cell and Cell‐Matrix Adhesion Functions

1990 • 345 citations

Recognition of distinct adhesive sites on fibrinogen by related integrins on platelets and endothelial cells

1989 • 343 citations

Characterization of the cell surface heterodimer VLA-4 and related peptides.

1987 • 340 citations

Examination of the platelet membrane glycoprotein IIb-IIIa complex and its interaction with fibrinogen and other ligands by electron microscopy.

1992 • 309 citations

Regulated expression of the Mac-1, LFA-1, p150,95 glycoprotein family during leukocyte differentiation.

1986 • 298 citations

Effect of platelet activation on the conformation of the plasma membrane glycoprotein IIb-IIIa complex

1991 • 270 citations

Electron microscopy and structural model of human fibronectin receptor.

1988 • 265 citations

Evidence that three adhesive proteins interact with a common recognition site on activated platelets.

1984 • 254 citations

Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets.

1989 • 250 citations

An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in an divalent cation-dependent functional complex with the disialoganglioside GD2.

1987 • 246 citations

Induction of the fibrinogen receptor on human platelets by intracellular mediators.

1987 • 240 citations

Inhibition of fibrinogen binding to GP IIb-IIIa by a GP IIIa peptide

1991 • 221 citations

A monoclonal antibody against the platelet fibrinogen receptor contains a sequence that mimics a receptor recognition domain in fibrinogen

1989 • 213 citations

A discrete sequence in a platelet integrin is involved in ligand recognition

1991 • 204 citations

Prostacyclin inhibits mobilisation of fibrinogen-binding sites on human ADP- and thrombin-treated platelets

1980 • 193 citations

The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering.

1987 • 186 citations

Activated phosphoinositide 3-kinase associates with membrane skeleton in thrombin-exposed platelets.

1992 • 186 citations

Modulation of vitronectin receptor binding by membrane lipid composition.

1990 • 180 citations

Calcium as a potential physiological regulator of integrin-mediated cell adhesion

1991 • 173 citations

Localization of internal pools of membrane glycoproteins involved in platelet adhesive responses.

1986 • 164 citations

Integrin modulating factor-1: A lipid that alters the function of leukocyte integrins

1992 • 163 citations

Immunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells.

1986 • 152 citations

Platelet-collagen adhesion: inhibition by a monoclonal antibody that binds glycoprotein IIb.

1984 • 148 citations

Activation-dependent recognition by hematopoietic cells of the LDV sequence in the V region of fibronectin.

1992 • 140 citations

T cell receptor-dependent, antigen-specific stimulation of a murine T cell clone induces a transient, VLA protein-mediated binding to extracellular matrix.

1991 • 125 citations

Inhibition of platelet function with synthetic peptides designed to be high-affinity antagonists of fibrinogen binding to platelets.

1986 • 123 citations

Ligand Binding to GPIIb-IIIa: A Status Report

1992 • 118 citations

Suppressor effects and cyclic AMP accumulation by the CD29 molecule of CD4+ lymphocytes

1989 • 109 citations

Thrombin stimulates the production of a novel polyphosphoinositide in human platelets.

1990 • 107 citations

Induction of the fibrinogen receptor on human platelets by epinephrine and the combination of epinephrine and ADP.

1980 • 107 citations

Effect of calcium on the stability of the platelet membrane glycoprotein IIb-IIIa complex.

1985 • 105 citations

Cation-dependent changes in the binding specificity of the platelet receptor GPIIb/IIIa.

1990 • 101 citations

Selective inactivation of the Arg-Gly-Asp-Ser (RGDS) binding site in von Willebrand factor by site-directed mutagenesis.

1992 • 98 citations

The Role of Endogenously Formed Diacylglycerol in the Propagation and Termination of Platelet Activation

1989 • 98 citations

VLA Proteins In The Integrin Family: Structures, Functions, And Their Role On Leukocytes

1990 • 90 citations

Expression of recombinant platelet glycoprotein IIbIIIa results in a functional fibrinogen-binding complex

1989 • 90 citations

Identification of cell surface antigens present on murine hematopoietic stem cells.

1985 • 87 citations

Regulation of glycoprotein IIb-IIIa receptor function studied with platelets permeabilized by the pore-forming complement proteins C5b-9.

1992 • 84 citations

A role for prostaglandins and thromboxanes in the exposure of platelet fibrinogen receptors.

1981 • 79 citations

Molecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function.

1987 • 74 citations

The binding of fibrinogen to its platelet receptor.

1982 • 74 citations

The leukocyte integrin LFA-1 reconstituted by cDNA transfection in a nonhematopoietic cell line is functionally active and not transiently regulated.

1990 • 64 citations

Ligand binding specificity of the leukocyte response integrin expressed by human neutrophils.

1992 • 57 citations

Variants of the cell recognition site of fibronectin that retain attachment-promoting activity

1985 • 46 citations

Human leukocyte function‐associated antigens on lympho‐hemopoietic precursor cells

1986 • 44 citations

Ligand Inhibition of the Platelet Glycoprotein IIb-IIIa Complex Function as a Calcium Channel in Liposomes

1989 • 37 citations

Interaction of fibrinogen with its platelet receptor: kinetics and effect of pH and temperature

1981 • 34 citations

Collagen-induced platelet activation mainly involves the protein kinase C pathway

1990 • 33 citations

Platelet Membrane Glycoproteins: Functions In Cellular Interactions

1990 • 20 citations

Platelet receptors in hemostasis

1990 • 19 citations

Platelet vitronectin receptor expression differentiates Iraqi-Jewish from Arab patients with Glanzmann thrombasthenia in Israel

1991 • 13 citations

Glycoprotein IIIa is phosphorylated in intact human platelets

1990 • 5 citations

Prostaglandin endoperoxide analogues stimulate phospholipase C and protein phosphorylation during platelet shape change

1985 • 4 citations