Recognition of distinct adhesive sites on fibrinogen by related integrins on platelets and endothelial cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

1985 • 1,650 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

Exposure of platelet fibrinogen receptors by ADP and epinephrine.

1979 • 868 citations

A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa.

1983 • 780 citations

Human platelets possess an inducible and saturable receptor specific for fibrinogen.

1979 • 713 citations

Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization.

1980 • 653 citations

Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor.

1987 • 574 citations

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

1987 • 571 citations

Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors.

1988 • 481 citations

Platelet receptor recognition site on human fibrinogen. Synthesis and structure-function relationship of peptides corresponding to the carboxy-terminal segment of the .gamma. chain

1984 • 479 citations

Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to “integrin”.

1987 • 466 citations

Platelets have more than one binding site for von Willebrand factor.

1983 • 459 citations

The tetrapeptide analogue of the cell attachment site of fibronectin inhibits platelet aggregation and fibrinogen binding to activated platelets.

1985 • 437 citations

Localization of an Arg-Gly-Asp Recognition Site Within an Integrin Adhesion Receptor

1988 • 402 citations

A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells

1989 • 352 citations

Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen.

1982 • 324 citations

The amino acid sequence of the α-chain of human fibrinogen

1979 • 309 citations

Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin

1985 • 299 citations

The effect of plasma proteins on the interaction of platelets with glass surfaces.

1969 • 297 citations

Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibody.

1983 • 280 citations

[27] Arginine-glycine-aspartic acid adhesion receptors

1987 • 263 citations

Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets.

1982 • 261 citations

Increased surface expression of the membrane glycoprotein IIb/IIIa complex induced by platelet activation. Relationship to the binding of fibrinogen and platelet aggregation

1987 • 257 citations

Evidence that three adhesive proteins interact with a common recognition site on activated platelets.

1984 • 254 citations

Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor, and thrombospondin on thrombin-stimulated human platelets

1985 • 253 citations

The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunit.

1988 • 238 citations

The Preparation and Some Properties of Fibrinogen Precipitated from Human Plasma by Glycine.

1963 • 236 citations

An endothelial cell-dependent pathway of coagulation.

1985 • 212 citations

Interaction between fibrinogen and cultured endothelial cells. Induction of migration and specific binding.

1985 • 207 citations

Identification of the fibrinogen receptor on human platelets by photoaffinity labeling.

1982 • 197 citations

Platelet glycoprotein IIb-IIIa-like proteins mediate endothelial cell attachment to adhesive proteins and the extracellular matrix.

1987 • 185 citations

Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins

1987 • 168 citations

Platelet Interaction with Polymerizing Fibrin

1972 • 161 citations

gamma and alpha chains of human fibrinogen possess sites reactive with human platelet receptors.

1982 • 156 citations

The effect of fibrin on cultured vascular endothelial cells

1979 • 152 citations

Fibrinogen induces adhesion, spreading, and microfilament organization of human endothelial cells in vitro.

1987 • 151 citations

Glycoprotein Ic-IIa functions as an activation-independent fibronectin receptor on human platelets.

1988 • 137 citations

Arg-Gly-Asp recognition by a cell adhesion receptor requires its 130-kDa alpha subunit.

1987 • 137 citations

Histotypic angiogenesis in vitro: Light microscopic, ultrastructural, and radioautographic studies

1982 • 135 citations

Exposure of binding sites for vitronectin on platelets following stimulation.

1988 • 122 citations

Fibrinogen and Platelets in the Primary Arrest of Bleeding

1971 • 121 citations

Dependence of albumin–fibrinogen simple and competitive adsorption on surface properties of biomaterials

1979 • 118 citations

Fibrinogen and Adenosine Diphosphate-induced Aggregation of Platelets

1964 • 117 citations

Structure of Plasmic Degradation Products of Human Fibrinogen

1974 • 107 citations

Comparison of Human Plasma Fibrinogen Subfractions and Early Plasmic Fibrinogen Derivatives

1974 • 102 citations

Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody.

1985 • 100 citations

Heterogeneity of human fibrinogen: Possible relation to proteolysis by thrombin and plasmin as studied by SDS-polyacrylamide gel electrophoresis

1970 • 93 citations

Generation and characterization of peptide-specific antibodies that inhibit von Willebrand factor binding to glycoprotein IIb-IIIa without interacting with other adhesive molecules. Selectivity is conferred by Pro1743 and other amino acid residues adjacent to the sequence Arg1744-Gly1745-Asp1746.

1988 • 90 citations

Thrombin generation and fibrin formation following injury to rabbit neointima. Studies of vessel wall reactivity and platelet survival.

1982 • 87 citations

Platelet adherence to fibrin and collagen.

1968 • 68 citations

Statistical Analysis of Repetitive Subcloning by the Limiting Dilution Technique with a View Toward Ensuring Hybridoma Monoclonality

1983 • 64 citations

Quantitative studies on fibrinogen and low-density lipoprotein in human aortic intima

1973 • 46 citations

Fate of fibrinopeptides in the reaction between human plasmin and fibrinogen

1973 • 41 citations

Fibrin protofibril and fibrinogen binding to ADP-stimulated platelets: evidence for a common mechanism

1988 • 31 citations

A double-isotope study on incorporation of platelets and red cells into fibrin.

1977 • 19 citations

The endo-endothelial fibrin lining, a historical account

1983 • 17 citations