Lipoxygenase-mediated transformation of human low density lipoprotein to an oxidized and cytotoxic complex.

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Beyond Cholesterol

1989 • 6,533 citations

Free Radicals in Biology

1976 • 1,879 citations

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

1984 • 1,631 citations

[53] Lipoxygenase from soybeans

1981 • 919 citations

Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidation.

1984 • 826 citations

Measurement of cell numbers by means of the endogenous enzyme hexosaminidase. Applications to detection of lymphokines and cell surface antigens

1984 • 655 citations

Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid.

1983 • 623 citations

Lipoprotein oxidation and lipoprotein-induced cytotoxicity.

1983 • 545 citations

Monocytes and Neutrophils Oxidize Low Density Lipoprotein Making It Cytotoxic

1985 • 536 citations

PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH.

1986 • 489 citations

Lipid peroxide level in plasma of diabetic patients

1979 • 463 citations

Modification of human serum low density lipoprotein by oxidation — Characterization and pathophysiological implications

1987 • 400 citations

Lipid peroxide levels of serum lipoprotein fractions of diabetic patients

1981 • 305 citations

Enzymatic modification of low density lipoprotein by purified lipoxygenase plus phospholipase A2 mimics cell-mediated oxidative modification

1988 • 301 citations

Reductive inactivation of soybean lipoxygenase 1 by catechols: a possible mechanism for regulation of lipoxygenase activity

1987 • 281 citations

Oxygen-mediated heterogeneity of apo-low-density lipoprotein.

1978 • 276 citations

Antioxidant treatment of diabetic rats inhibits lipoprotein oxidation and cytotoxicity.

1989 • 265 citations

Inhibition of Tumor Promotion by a Biomimetic Superoxide Dismutase

1983 • 256 citations

Superoxide anion participation in human monocyte-mediated oxidation of low-density lipoprotein and conversion of low-density lipoprotein to a cytotoxin.

1989 • 231 citations

Biochemistry of Arachidonic Acid Metabolism

1985 • 138 citations

Activated human monocytes oxidize low-density lipoprotein by a lipoxygenase-dependent pathway.

1990 • 132 citations

Toxicity of oxidized low‐density lipoprotein to cultured fibroblasts is selective for S phase of the cell cycle

1987 • 112 citations

Antitumor Effect of a Copper Coordination Compound With Superoxide Dismutase-Like Activity2

1981 • 82 citations

Oxidative modification of low density lipoprotein (LDL) by activated human monocytes and the cell lines U937 and HL60

1988 • 71 citations

Oxygenation of phosphatidylcholine by human polymorphonuclear leukocyte 15-lipoxygenase

1985 • 60 citations

Inactivation of Lipoxygenase by Hydrogen Peroxide, Cysteine and Some Other Reagents

1967 • 41 citations

Effects of reagent and cell-generated hydrogen peroxide on the properties of low density lipoprotein.

1986 • 33 citations

Localization of 5-lipoxygenase within human polymorphonuclear leukocytes

1985 • 18 citations

Inactivation of Lipoxygenase by Hydrogen Peroxide, Cysteine and Some Other Reagents

1967 • 14 citations