Antibodies to Synthetic Peptide from the Residue 33 to 42 Domain of c-Ha-ras p21 Block Reconstitution of the Protein with Different Effectors

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants

1987 • 1,197 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1985 • 913 citations

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1982 • 836 citations

Antibodies to Bradykinin and Angiotensin: A Use of Carbodiimides in Immunology

1964 • 820 citations

The ras gene family and human carcinogenesis

1988 • 786 citations

Requirement for c-ras proteins during viral oncogene transformation

1986 • 680 citations

Cloning of bovine GAP and its interaction with oncogenic ras p21

1988 • 666 citations

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

1976 • 623 citations

ras GTPase activating protein: Signal transmitter and signal terminator

1989 • 621 citations

Guanosine Triphosphatase Activating Protein (GAP) Interacts with the p21 ras Effector Binding Domain

1988 • 533 citations

Three-Dimensional Structure of an Oncogene Protein: Catalytic Domain of Human c-H- ras P21

1988 • 532 citations

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product

1988 • 402 citations

Functional homology of mammalian and yeast RAS genes

1985 • 324 citations

Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.

1986 • 291 citations

Purification of ras GTPase activating protein from bovine brain.

1988 • 255 citations

IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae.

1989 • 251 citations

Chemistry of Antibody Binding to a Protein

1987 • 251 citations

Ras p21 as a Potential Mediator of Insulin Action in Xenopus Oocytes

1987 • 224 citations

Mammalian and Yeast ras Gene Products: Biological Function in Their Heterologous Systems

1985 • 209 citations

Mutational analysis of a ras catalytic domain.

1986 • 205 citations

Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins.

1987 • 183 citations

Suppression of defective RAS1 and RAS2 functions in yeast by an adenylate cyclase activated by a single amino acid change.

1986 • 93 citations

Biochemical Properties of a Highly Purified v-ras^H p21 Protein Overproduced in Escherichia coli and Inhibition of Its Activities by a Monoclonal Antibody

1985 • 65 citations

Reversal of transformed phenotype by monoclonal antibodies against Ha-ras p21 proteins

1986 • 65 citations

Chemical synthesis of a gene coding for human angiogenin, its expression in Escherichia coli and conversion of the product into its active form

1987 • 55 citations

Neutralizing monoclonal antibody against ras oncogene product p21 which impairs guanine nucleotide exchange.

1987 • 50 citations

Monoclonal antibody Y13-259 recognizes an epitope of the p21 ras molecule not directly involved in the GTP-binding activity of the protein.

1986 • 49 citations

Characterization of a factor that stimulates hydrolysis of GTP bound to ras gene product p21 (GTPase-activating protein) and correlation of its activity to cell density.

1988 • 47 citations

Expression of normal and activated human Ha-ras cDNAs in Saccharomyces cerevisiae.

1985 • 33 citations

H-ras Mutants Lacking the Epitope for the Neutralizing Monoclonal Antibody Y13-259 Show Decreased Biological Activity and Are Deficient in GTPase-Activating Protein Interaction

1989 • 19 citations

Absolute values of ras p21 defined by direct binding liquid competition radioimmunoassays

1987 • 12 citations

Inhibition of yeast adenylate cyclase by antibodies to ras p21

1988 • 3 citations