PDGF A chain homodimers drive proliferation of bipotential (O-2A) glial progenitor cells in the developing rat optic nerve.

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

1973 • 3,279 citations

Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

1979 • 2,285 citations

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1983 • 2,009 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes

1984 • 1,638 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Monoclonal antibody to a plasma membrane antigen of neurons.

1979 • 965 citations

Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside.

1982 • 842 citations

Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor ceil

1988 • 833 citations

Galactocerebroside is a specific cell-surface antigenic marker for oligodendrocytes in culture

1978 • 813 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture

1988 • 760 citations

A role for platelet-derived growth factor in normal gliogenesis in the central nervous system

1988 • 756 citations

Two Classes of PDGF Receptor Eecognize Different Isoforms of PDGF

1988 • 603 citations

Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.

1988 • 514 citations

Evidence for migration of oligodendrocyte–type-2 astrocyte progenitor cells into the developing rat optic nerve

1987 • 471 citations

A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains

1986 • 418 citations

Quantitative analysis ofin situhybridization methods for the detection of actin gene expression

1985 • 370 citations

Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve I. Cell proliferation

1976 • 364 citations

Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments.

1984 • 352 citations

Cellular localization of nerve growth factor synthesis by in situ hybridization.

1987 • 345 citations

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules.

1988 • 338 citations

Purified astrocytes promote the in vitro division of a bipotential glial progenitor cell.

1984 • 336 citations

A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain.

1988 • 317 citations

A quantitative immunohistochemical study of macroglial cell development in the rat optic nerve: In vivo evidence for two distinct astrocyte lineages

1985 • 316 citations

Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve. II. Time of origin

1976 • 315 citations

Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class.

1988 • 314 citations

Reconstitution of a developmental clock in vitro: a critical role for astrocytes in the timing of oligodendrocyte differentiation

1985 • 296 citations

Epithelioid and fibroblastic rat kidney cell clones: Epidermal growth factor (EGF) receptors and the effect of mouse sarcoma virus transformation

1978 • 296 citations

A glioma-derived PDGF a chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets

1988 • 264 citations

Purification and properties of porcine platelet-derived growth factor.

1984 • 260 citations

Spatial segregation of mRNA encoding myelin-specific proteins.

1987 • 235 citations

Two glial cell lineages diverge prenatally in rat optic nerve

1984 • 232 citations

PDGF receptors on cells of the oligodendrocyte-type-2 astrocyte (O-2A) cell lineage

1989 • 224 citations

Detection of the nicotinic acetylcholine receptor alpha-subunit mRNA by in situ hybridization at neuromuscular junctions of 15-day-old chick striated muscles.

1988 • 217 citations

Detection of human white cell proliferative responses by immunoenzymatic measurement of bromodeoxyuridine uptake

1988 • 148 citations

Characterization of a slowly proliferative cell along the oligodendrocyte differentiation pathway.

1987 • 134 citations

Alternative RNA splicing affects function of encoded platelet-derived growth factor A chain

1987 • 130 citations

Transforming Potential of Human c- sis Nucleotide Sequences Encoding Platelet-Derived Growth Factor

1984 • 127 citations

Different effects of homo- and heterodimers of platelet-derived growth factor A and B chains on human and mouse fibroblasts.

1988 • 102 citations

cDNA clones reveal differences between human glial and endothelial cell platelet-derived growth factor A-chains

1987 • 99 citations

A Common PDGF rEceptor Is Activated by Homodimeric A and B Forms of PDGF

1988 • 85 citations

cDNA Cloning and Expression of a Human Platelet-Derived Growth Factor (PDGF) Receptor Specific for B-Chain-Containing PDGF Molecules

1988 • 76 citations

[1] Purification of human platelet-derived growth factor

1987 • 50 citations