Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

A Platelet-Dependent Serum Factor That Stimulates the Proliferation of Arterial Smooth Muscle Cells In Vitro

1974 • 1,838 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Platelets as a source of fibroblast growth-promoting activity

1974 • 625 citations

Purification of human platelet-derived growth factor.

1979 • 586 citations

Platelet-derived growth factor. I. High yield purification and evidence for multiple forms.

1982 • 457 citations

Characterization of a cDNA coding for human factor VII.

1986 • 450 citations

Isolation and expression of an altered mouse dihydrofolate reductase cDNA.

1983 • 436 citations

Platelet-derived growth factor: purification and partial characterization.

1979 • 436 citations

A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains

1986 • 418 citations

Acceleration of nucleic acid hybridization rate by polyethylene glycol

1986 • 383 citations

The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor.

1984 • 376 citations

Human platelet-derived growth factor. Purification and resolution into two active protein fractions.

1981 • 353 citations

Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes.

1982 • 293 citations

Platelet-derived growth factor: Identification of constituent polypeptide chains

1982 • 275 citations

Purification and properties of porcine platelet-derived growth factor.

1984 • 260 citations

Evidence for the platelet-derived growth factor-stimulated tyrosine phosphorylation of the platelet-derived growth factor receptor in vivo. Immunopurification using a monoclonal antibody to phosphotyrosine.

1984 • 209 citations

Platelet-derived growth factor receptors form a high affinity state in membrane preparations. Kinetics and affinity cross-linking studies.

1984 • 207 citations

Characterization of platelet-derived growth factor-stimulated phosphorylation in cell membranes.

1983 • 147 citations

Characterization of the receptor for platelet-derived growth factor on human fibroblasts. Demonstration of an intimate relationship with a 185,000-Dalton substrate for the platelet-derived growth factor-stimulated kinase.

1983 • 144 citations

Platelet-derived growth factor. III. Identification of a platelet-derived growth factor receptor by affinity labeling.

1982 • 137 citations

[8] methods for studying the platelet-derived growth factor receptor

1985 • 117 citations

Synthesis, phosphorylation, and degradation of multiple forms of the platelet-derived growth factor receptor studied using a monoclonal antibody.

1987 • 102 citations

An inversion that disrupts the Antennapedia gene causes abnormal structure and localization of RNAs

1986 • 96 citations

Expression of active human factor IX in transfected cells

1985 • 82 citations

Purification of the platelet-derived growth factor receptor by using an anti-phosphotyrosine antibody.

1985 • 75 citations

Conversion of low-affinity interleukin 2 receptors to a high-affinity state following fusion of cell membranes.

1986 • 64 citations

Purified human platelet-derived growth factor receptor has ligand-stimulated tyrosine kinase activity.

1986 • 64 citations

Effect of methylation on expression of microinjected genes.

1982 • 61 citations

The B chain of PDGF alone is sufficient for mitogenesis.

1985 • 50 citations

Isolation and Expression of cDNAs Encoding Human Factor VII

1986 • 42 citations