Antioxidant defense mechanisms of endothelial cells: glutathione redox cycle versus catalase

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

Purification and characterization of the flavoenzyme glutathione reductase from rat liver.

1975 • 1,938 citations

[48] Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples

1981 • 1,564 citations

H2O2 release from human granulocytes during phagocytosis. I. Documentation, quantitation, and some regulating factors.

1975 • 653 citations

Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells.

1981 • 587 citations

Adult Respiratory-Distress Syndrome

1982 • 554 citations

METABOLIC PATTERNS IN THREE TYPES OF PHAGOCYTIZING CELLS

1963 • 500 citations

Metabolism of hydrogen peroxide in isolated hepatocytes: Relative contributions of catalase and glutathione peroxidase in decomposition of endogenously generated H2O2

1981 • 336 citations

Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide.

1984 • 334 citations

A study of the inhibition of catalase by 3-amino-1:2:4-triazole

1958 • 251 citations

Glutathione depletion sensitizes tumor cells to oxidative cytolysis.

1982 • 214 citations

Severe generalized glutathione reductase deficiency after antitumor chemotherapy with BCNU" [1,3-bis(chloroethyl)-1-nitrosourea].

1977 • 176 citations

Interactions of granulocytes with the lungs.

1984 • 146 citations

Lung Cell Oxidant Injury

1982 • 121 citations

Pseudomonas aeruginosa cytotoxin stimulates prostacyclin production in cultured pulmonary artery endothelial cells: Membrane attack and calcium influx

1985 • 69 citations

Inhibition of human polymorphonuclear leukocyte function by 2-cyclohexene-1-one. A role for glutathione in cell activation.

1981 • 36 citations

Decreased Bactericidal Function and Impaired Respiratory Burst in Lung Macrophages after Sustained in vitro Hyperoxia

1983 • 33 citations

[48] Endothelial culture, neutrophil or enzymic generation of free radicals: In vitro methods for the study of endothelial injury

1984 • 28 citations