Pseudomonas aeruginosa cytotoxin stimulates prostacyclin production in cultured pulmonary artery endothelial cells: Membrane attack and calcium influx

Calmodulin Plays a Pivotal Role in Cellular Regulation

1980 • 2,441 citations

Intracellular phospholipases A

1980 • 989 citations

23. Immunization, Isolation of Immunoglobulins, Estimation of Antibody Titre

1973 • 878 citations

Applied Statistics: Analysis of Variance and Regression.

1976 • 608 citations

Adult Respiratory-Distress Syndrome

1982 • 554 citations

On the mechanism of membrane damage by Staphylococcus aureus alpha-toxin.

1981 • 369 citations

New Perspectives on Calcium Antagonists

1982 • 310 citations

Selective inhibition by mepacrine of the release of “rabbit aorta contracting substance” evoked by the administration of bradykinin

1972 • 249 citations

Sites of action of Ca2+ channel inhibitors

1983 • 224 citations

Pharmacological evaluation of a new Ca2+ antagonist, 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8): Studies in smooth muscles

1974 • 217 citations

Characterization of prostacyclin synthesis in cultured human arterial smooth muscle cells, venous endothelial cells and skin fibroblasts

1979 • 185 citations

Applied Statistics: Analysis of Variance and Regression

1975 • 184 citations

Calcium and Cell Function

1984 • 178 citations

Inhibition of polymorphonuclear leukocyte adherence by prostacyclin.

1980 • 177 citations

Staphylococcal alpha-toxin: oligomerization of hydrophilic monomers to form amphiphilic hexamers induced through contact with deoxycholate detergent micelles.

1981 • 177 citations

Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition

1976 • 176 citations

Activity-structure relationship of calmodulin antagonists, Naphthalenesulfonamide derivatives.

1981 • 163 citations

Differential effects of calmodulin antagonists on phospholipases A2 and C in thrombin-stimulated platelets.

1981 • 152 citations

Bradykinin-induced release of prostacyclin and thromboxanes from bovine pulmonary artery endothelial cells studies with lower homologs and calcium antagonists

1983 • 149 citations

Role of Ca2+ and cyclic AMP in the regulation of the production of prostacyclin by the vascular endothelium.

1982 • 140 citations

Stimulation of prostaglandin formation by vasoactive mediators in cultured human endothelial cells

1982 • 139 citations

Pseudomonas aeruginosa Infections: Persisting Problems and Current Research to Find New Therapies

1975 • 134 citations

Staphylococcal alpha-toxin-induced PGI2 production in endothelial cells: role of calcium

1985 • 125 citations

Lung Cell Oxidant Injury

1982 • 121 citations

Consequences of cell membrane attack by complement: release of arachidonate and formation of inflammatory derivatives.

1983 • 110 citations

Mechanism of bradykinin-stimulated prostacyclin synthesis in porcine aortic endothelial cells

1982 • 100 citations

Bradykinin stimulates phospholipid methylation, calcium influx, prostaglandin formation, and cAMP accumulation in human fibroblasts.

1983 • 85 citations

The role of calcium in the regulation of prostacyclin synthesis by porcine aortic endothelial cells

1984 • 85 citations

“Prostaglandins and cardiovascular system”

1981 • 83 citations

Ca2+.Calmodulin-dependent release of arachidonic acid for renal medullary prostaglandin synthesis. Evidence for involvement of phospholipases A2 and C.

1983 • 77 citations

Prostacyclin release from cultured and ex vivo bovine vascular endothelium. Studies with thrombin, arachidonic acid, and ionophore A23187.

1981 • 69 citations

SYNTHESIS OF FACTOR VIII BY ENDOTHELIAL CELLS

1982 • 64 citations

Possible conformation of delta-lysin, a membrane-damaging peptide of Staphylococcus aureus

1982 • 62 citations

Purification of a cytotoxic protein from Pseudomonas aeruginosa

1979 • 60 citations

Specificity of Trifluoperazine and Related Phenothiazines for Calcium-Binding Proteins

1982 • 56 citations

Evidence that the effects of thrombin on arachidonate metabolism in cultured human endothelial cells are not mediated by a high affinity receptor.

1980 • 53 citations

Cytotoxic effects of leukocidin from Pseudomonas aeruginosa on polymorphonuclear leukocytes from cattle

1976 • 40 citations

A Novel Cellular Signaling System Based on the Integration of Phospholipid and Calcium Metabolism

1982 • 34 citations

Staphylococcal delta toxin stimulates endogenous phospholipase A2 activity and prostaglandin synthesis in fibroblasts

1981 • 29 citations

Prostacyclin production by endothelial cells

1984 • 29 citations

Metabolic Activities of the Lung

1981 • 27 citations

Permeability changes of Ehrlich mouse ascites tumor cells induced by a cytotoxin from Pseudomonas aeruginosa

1982 • 24 citations

Generation of Leukotrienes and Lipoxygenasefactors from Human Polymorphonuclear Granulocytes During Bacterial Phagocytosis and Interaction with Bacterial Exotoxins

1983 • 24 citations

Metabolic Activities of the Lung.

1981 • 24 citations

Effects of a cytotoxic protein from on phagocytic and pinocytic cells: and studies

1983 • 23 citations

Mode of cytotoxic action of pseudomonal leukocidin on phosphatidylinositol metabolism and activation of lysosomal enzyme in rabbit leukocytes

1984 • 22 citations

Chapter 4 The leukotrienes and other lipoxygenase products

1983 • 21 citations

Lower nephron toxicity of a highly purified cytotoxin from Pseudomonas aeruginosa in rats

1982 • 10 citations