Decreased inducible expression of CD80 and CD86 in human monocytes after ultraviolet-B irradiation: its involvement in inactivation of allogenecity

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1992 • 1,573 citations

The B7 and CD28 receptor families

1994 • 1,342 citations

The Role of the CD28 Receptor During T Cell Responses to Antigen

1993 • 1,320 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation

1993 • 911 citations

B70 antigen is a second ligand for CTLA-4 and CD28

1993 • 907 citations

The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells.

1990 • 799 citations

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

1991 • 660 citations

Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1.

1993 • 494 citations

CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL.

1995 • 489 citations

B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.

1991 • 445 citations

CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes.

1992 • 342 citations

The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells.

1991 • 335 citations

Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity

1994 • 334 citations

Selective induction of B7/BB-1 on interferon-γ stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway

1991 • 325 citations

Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression

1992 • 285 citations

The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro.

1992 • 273 citations

Vascular cell adhesion molecule 1 induces T-cell antigen receptor-dependent activation of CD4+T lymphocytes.

1991 • 234 citations

Alloimmunization against the MHC antigens after platelet transfusions is due to contaminating leukocytes in the platelet suspension.

1981 • 226 citations

Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-kB-like response element

1991 • 194 citations

Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor.

1988 • 173 citations

Involvement of CD28 in MHC-unrestricted cytotoxicity mediated by a human natural killer leukemia cell line.

1992 • 159 citations

Inhibition of epidermal Langerhans cell function by low dose ultraviolet B radiation. Ultraviolet B radiation selectively modulates ICAM-1 (CD54) expression by murine Langerhans cells.

1991 • 148 citations

Inability of UV-Irradiated Lymphocytes to Stimulate Allogeneic Cells in Mixed Lymphocyte Culture

1971 • 114 citations

Prevention of platelet alloimmunization in dogs with systemic cyclosporine and by UV-irradiation or cyclosporine-loading of donor platelets

1987 • 104 citations

Intercellular adhesion molecule-2, a second counter-receptor for CD11a/CD18 (leukocyte function-associated antigen-1), provides a costimulatory signal for T-cell receptor-initiated activation of human T cells.

1992 • 95 citations

Blood Transfusion and Immunomodulation: A Possible Mechanism

1993 • 90 citations

Cell membrane is a major locus for ultraviolet B-induced alterations in accessory cells.

1990 • 86 citations

Interferon production by human and murine lymphocytes in response to alloantigens.

1980 • 86 citations

Ultraviolet irradiation of blood prevents transfusion-induced sensitization and marrow graft rejection in dogs

1986 • 77 citations

Vitrification of human monocytes

1986 • 66 citations

Induction of costimulatory molecule B7 in M12 B lymphomas by cAMP or MHC-restricted T cell interaction.

1993 • 65 citations

Alteration in Murine Epidermal Langerhans Cell Population by Various UV Irradiations: Quantitative and Morphologic Studies on the Effects of Various Wavelengths of Monochromatic Radiation on Ia-Bearing Cells

1985 • 61 citations

Immunomodulation by ultraviolet light: clinical studies and biological effects

1991 • 61 citations

High-dose UV-B radiation alters human dendritic cell costimulatory activity but does not allow dendritic cells to tolerize T lymphocytes to alloantigen in vitro

1993 • 38 citations

UV irradiation of lymphocytes triggers an increase in intracellular Ca2+ and prevents lectin-stimulated Ca2+ mobilization: evidence for UV- and nifedipine-sensitive Ca2+ channels.

1991 • 29 citations

Generation of Active Oxygens, Cell Deformation and Membrane Potential Changes upon UV-B Irradiation in Human Blood Cells.

1994 • 29 citations

Stimulation of T-cell activation by UV-treated, antigen-pulsed macrophages: Evidence for a requirement for antigen processing and interleukin 1 secretion

1983 • 27 citations

Effective ultraviolet irradiation of platelet concentrates in teflon bags

1990 • 27 citations

Ultraviolet B-induced loss of HLA class II antigen expression on lymphocytes is dose, time, and locus dependent.

1990 • 24 citations

The accessory function of B lymphocytes is resistant to the adverse effects of UV radiation

1991 • 24 citations

Deleterious effect of ultraviolet-B radiation on accessory function of human blood adherent mononuclear cells.

1987 • 23 citations

Synergistic action of near-UV and phenylalanine, tyrosine or tryptophan on the inactivation of phage T7: Role of superoxide radicals and hydrogen peroxide

1994 • 20 citations

Ultraviolet-B irradiation of platelet concentrates: a strategy to reduce transfusion recipient allosensitization.

1992 • 18 citations

Exquisite sensitivity of dendritic cells to ultraviolet radiation and temperature changes.

1989 • 13 citations

UV irradiation can induce in vitro clonal anergy in alloreactive cytotoxic T lymphocytes

1993 • 12 citations

Ultraviolet Irradiation Inhibits Killer‐Target Cell Interaction

1993 • 7 citations

RESTORATION OF LYMPHOCYTE PROLIFERATION AND CTL GENERATION BY MURINE rIL-2 AFTER TREATMENT OF ALLOGENEIC STIMULATOR CELLS BY ULTRAVIOLET B IRRADIATION, HEAT, OR PARAFORMALDEHYDE

1991 • 3 citations

Accessory cell damage and loss of overall white cell viability inhibit lymphocyte responses after ultraviolet‐B irradiation but without evidence of in vitro suppression

1992 • 3 citations

The Role of UV Irradiation in the Prevention of HLA Alloimmunization and in Therapeutic Apheresis.

1992 • 3 citations

Potential Involvement of Free Radical Reactions in Inactivating Antigen Presenting Cells by Ultraviolet-B Irradiation

1993 • 2 citations

The mechanism of leukocyte inactivation by Ultraviolet-B irradiation: Changes of leukocyte morphology.

1994 • 1 citations