Gene products required for chromosome separation

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Methods in cell physiology

1964 • 1,816 citations

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

1987 • 1,153 citations

DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1987 • 691 citations

Protein Phosphatases: Properties and Role in Cellular Regulation

1983 • 645 citations

The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe

1988 • 493 citations

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases

1989 • 486 citations

The NDA3 gene of fission yeast encodes β-tubulin: A cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis

1984 • 473 citations

Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization.

1984 • 444 citations

The bimG gene of Aspergillus nidulans, required for completion of anaphase, encodes a homolog of mammalian phosphoprotein phosphatase 1

1989 • 326 citations

Isolation and characterization of Schizosaccharomyces pombe cut mutants that block nuclear division but not cytokinesis

1986 • 292 citations

Mitotic spindle pulls but fails to separate chromosomes in type II DNA topoisomerase mutants: uncoordinated mitosis

1986 • 292 citations

Localization of F-actin through the cell division cycle of Schizosaccharomyces pombe

1985 • 280 citations

Higher order chromosome structure is affected by cold-sensitive mutations in a Schizosaccharomyces pombe gene crm1+ which encodes a 115-kD protein preferentially localized in the nucleus and its periphery.

1989 • 246 citations

A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase.

1988 • 220 citations

Growth Polarity And Cytokinesis In Fission Yeast: The Role Of The Cytoskeleton

1986 • 216 citations

Identification of the pleiotropic cell division cycle gene NDA2 as one of two different α-tubulin genes in schizosaccharomyces pombe

1984 • 216 citations

Cold-sensitive and caffeine-supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosis.

1988 • 210 citations

Regulation of MPF activity in vitro

1988 • 209 citations

An electrophoretic karyotype forSchizosaccharomyces pombeby pulsed field gel electrophoresis

1987 • 206 citations

Composite motifs and repeat symmetry in S. pombe centromeres: Direct analysis by integration of Notl restriction sites

1989 • 205 citations

Construction of aNotI restriction map of the fission yeastSchizosaccharomyces pombegenome

1989 • 204 citations

Chromosome walking shows a highly homologous repetitive sequence present in all the centromere regions of fission yeast

1986 • 188 citations

Involvement of a type 1 protein phosphatase encoded by bws1+ in fission yeast mitotic control

1989 • 188 citations

Cold-sensitive nuclear division arrest mutants of the fission yeast Schizosaccharomyces pombe

1983 • 165 citations

Two cell division cycle genes NDA2 and NDA3 of the fission yeast Schizosaccharomyces pombe control microtubular organization and sensitivity to anti-mitotic benzimidazole compounds

1983 • 150 citations

Mitosis in the fission yeast Schizosaccharomyces pombe as revealed by freeze-substitution electron microscopy

1986 • 137 citations

Sequential alterations in the nuclear chromatin region during mitosis of the fission yeast Schizosa Ccharomyces Pombe-: Video fluorescence microscopy of synchronously growing wild-type and cold-sensitive cdc mutants by using a dna-binding fluorescent probe

1981 • 135 citations

Isolation and sequence analysis of a cDNA clone encoding a type‐1 protein phosphatase catalytic subunit: Homology with protein phosphatase 2A

1987 • 128 citations

The nucleotide sequence of the fission yeast DNA topoisomerase II gene: structural and functional relationships to other DNA topoisomerases.

1986 • 119 citations

Two isoforms of protein phosphatase 1 may be produced from the same gene

1988 • 108 citations

Genetic nomenclature and gene list of the fission yeast Schizosaccharomyces pombe

1987 • 95 citations

Cloning and sequencing ofSchizosaccharomyces pombeDNA topoisomerase I gene, and effect of gene disruption

1987 • 85 citations

Essential roles of the RNA polymerase I largest subunit and DNA topoisomerases in the formation of fission yeast nucleolus.

1989 • 84 citations

A single intronless actin gene in the fission yeastSchizosaccharomyces pombe: nucleotide sequence and transcripts formed in homologous and heterologous yeast

1987 • 78 citations

Visualization of chromosomes in mitotically arrested cells of the fission yeast Schizosaccharomyces pombe

1983 • 70 citations

In vivo actions of protein phosphatase inhibitor‐2 inXenopusoocytes

1982 • 34 citations

Yeast DNA Topoisomerases and Their Structural Genes

1987 • 30 citations

Yeast tubulin genes.

1987 • 13 citations