Expression of Thrombin Receptors in Human Atherosclerotic Coronary Arteries Leads to an Exaggerated Vasoconstrictory Response In Vitro

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1991 • 2,981 citations

Paradoxical Vasoconstriction Induced by Acetylcholine in Atherosclerotic Coronary Arteries

1986 • 2,422 citations

Molecular cloning of a potential proteinase activated receptor.

1994 • 887 citations

Superoxide and peroxynitrite inatherosclerosis.

1994 • 674 citations

Effect of hypercholesterolemia on vascular reactivity in the rabbit. I. Endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and hypercholesterolemic rabbits.

1986 • 535 citations

Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5'-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta.

1987 • 534 citations

Endothelial dysfunction of the coronary microvasculature is associated with coronary blood flow regulation in patients with early atherosclerosis.

1991 • 531 citations

Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta.

1990 • 527 citations

Atherosclerosis impairs endothelium-dependent vascular relaxation to acetylcholine and thrombin in primates.

1986 • 406 citations

Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits.

1991 • 403 citations

Augmented responses to vasoconstrictor stimuli in hypercholesterolemic and atherosclerotic monkeys.

1984 • 375 citations

Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholesterolemia and atherosclerosis.

1989 • 357 citations

Endothelium-dependent inhibitory effects of acetylcholine, adenosine triphosphate, thrombin and arachidonic acid in the canine femoral artery.

1982 • 345 citations

Coronary Vascular Reactivity After Acute Myocardial Ischemia

1982 • 336 citations

Thrombin receptor expression in normal and atherosclerotic human arteries.

1992 • 318 citations

Characterization of a functional thrombin receptor. Issues and opportunities.

1992 • 274 citations

Dietary antioxidants preserve endothelium-dependent vessel relaxation in cholesterol-fed rabbits.

1993 • 204 citations

Physiologic consequences of increased vascular oxidant stresses in hypercholesterolemia and atherosclerosis: Implications for impaired vasomotion

1995 • 170 citations

L-arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbits.

1991 • 165 citations

Cholesterol feeding impairs endothelium-dependent relaxation of rabbit aorta

1985 • 125 citations

Mechanisms of Thrombin Receptor Agonist Specificity

1995 • 118 citations

Thrombin-Mediated Increase in Vascular Endothelial Permeability

1992 • 97 citations

Thrombin as a Multifunctional Protein: Induction of Cell Adhesion and Proliferation

1992 • 88 citations

Mechanisms of adenosine triphosphate-, thrombin-, and trypsin-induced relaxation of rat thoracic aorta.

1984 • 82 citations

Receptor Mechanism of Thrombin-Induced Endothelium-Dependent and Endothelium-Independent Coronary Vascular Effects in Dogs

1993 • 66 citations

Role of the thrombin receptor in restenosis and atherosclerosis

1995 • 50 citations

Mechanism of Thrombin-Induced Endothelium-Dependent Coronary Vasodilation in Dogs: Role of its Proteolytic Enzymatic Activity

1986 • 39 citations

Human coronary vascular smooth muscle and endothelium-dependent responses after storage at −75 °C

1992 • 32 citations

Distinct receptors and signaling pathways in alpha-thrombin- and thrombin receptor peptide-induced vascular contractions.

1994 • 30 citations