Activity and safety of DNA plasmids encoding IL-4 and IFN gamma

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets

1998 • 1,569 citations

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

1996 • 1,078 citations

Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.

1993 • 888 citations

IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses.

1988 • 731 citations

Contribution of CpG motifs to the immunogenicity of DNA vaccines.

1997 • 519 citations

Vaccination against tuberculosis by DNA injection

1996 • 513 citations

Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines

1995 • 486 citations

Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.

1994 • 453 citations

Vaccination with a Plasmid Vector Carrying the Rabies Virus Glycoprotein Gene Induces Protective Immunity against Rabies Virus

1994 • 393 citations

In vivo engineering of a cellular immune response by co-administration of IL-12 expression vector with a DNA immunogen

1997 • 347 citations

Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA

1993 • 344 citations

Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines.

1997 • 307 citations

In vivo engineering of a cellular immune response by coadministration of IL-12 expression vector with a DNA immunogen.

1997 • 286 citations

Intranasal immunization of a DNA vaccine with IL-12- and granulocyte-macrophage colony-stimulating factor (GM-CSF)-expressing plasmids in liposomes induces strong mucosal and cell-mediated immune responses against HIV-1 antigens.

1997 • 278 citations

Development of Th1 and Th2 Populations and the Nature of Immune Responses to Hepatitis B Virus DNA Vaccines Can Be Modulated by Codelivery of Various Cytokine Genes

1998 • 267 citations

Enhancement of cellular and humoral immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids.

1997 • 257 citations

Modulation of amplitude and direction ofin vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens

1998 • 241 citations

Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector.

1996 • 181 citations

Do DNA Vaccines Induce Autoimmune Disease?

1997 • 178 citations

Systemic immunological effects of cytokine genes injected into skeletal muscle.

1993 • 174 citations

A Plasmid Encoding Murine Granulocyte-Macrophage Colony-Stimulating Factor Increases Protection Conferred by a Malaria DNA Vaccine

1998 • 171 citations

Enhancement of cell-mediated immunity against HIV-1 induced by coinnoculation of plasmid-encoded HIV-1 antigen with plasmid expressing IL-12.

1997 • 147 citations

Immunity in early life

1998 • 132 citations

Towards a DNA vaccine against tuberculosis

1994 • 122 citations

Cytokines and costimulatory molecules as genetic adjuvants

1997 • 102 citations

DNA vaccines: safety and efficacy issues

1997 • 89 citations

Role of adjuvants in the modulation of antibody isotype, specificity, and induction of protection by whole blood-stage Plasmodium yoelii vaccines.

1993 • 58 citations

The effect of interferon-γ on genetic immunization

1997 • 45 citations

<scp>ELISPOT</scp> Assay to Detect Cytokine‐Secreting Murine and Human Cells

1994 • 40 citations

Immunogenicity and Efficacy of a DNA Vaccine in Aged Mice

1998 • 17 citations

Long-Term Effect of Primary Immunization on Subsequent Immune Responsiveness

1997 • 14 citations

Plasmodium yoelii in mice: differential induction of cytokine gene expression during hyporesponsiveness induction and restimulation

1995 • 10 citations