Human Wild-Type α-Synuclein Impairs Neurogenesis

Staging of brain pathology related to sporadic Parkinson’s disease

2002 • 9,557 citations

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

1997 • 7,814 citations

Neurogenesis in the adult human hippocampus

1998 • 6,181 citations

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

1965 • 3,461 citations

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

1996 • 3,079 citations

Cell Death During Development of the Nervous System

1991 • 3,033 citations

Some new, simple and efficient stereological methods and their use in pathological research and diagnosis

1988 • 2,948 citations

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

1998 • 2,898 citations

Functional neurogenesis in the adult hippocampus

2002 • 2,813 citations

Long-Distance Neuronal Migration in the Adult Mammalian Brain

1994 • 2,291 citations

Cellular Composition and Three-Dimensional Organization of the Subventricular Germinal Zone in the Adult Mammalian Brain

1997 • 1,878 citations

Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone

1993 • 1,799 citations

Dopaminergic Loss and Inclusion Body Formation in α-Synuclein Mice: Implications for Neurodegenerative Disorders

2000 • 1,729 citations

Mice Lacking α-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine System

2000 • 1,628 citations

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

1998 • 1,546 citations

Neurogenesis in the Adult Rat: Electron Microscopic Analysis of Light Radioautographs

1977 • 1,438 citations

Doublecortin Is a Microtubule-Associated Protein and Is Expressed Widely by Migrating Neurons

1999 • 1,297 citations

Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat

1993 • 1,215 citations

Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

1997 • 1,206 citations

Doublecortin Is a Developmentally Regulated, Microtubule-Associated Protein Expressed in Migrating and Differentiating Neurons

1999 • 974 citations

Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

1998 • 949 citations

Characterization of a novel protein regulated during the critical period for song learning in the zebra finch

1995 • 826 citations

Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis

2003 • 788 citations

Becoming a new neuron in the adult olfactory bulb

2003 • 787 citations

The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis

2002 • 752 citations

Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF

1995 • 686 citations

Maturation and Death of Adult-Born Olfactory Bulb Granule Neurons: Role of Olfaction

2002 • 670 citations

Enriched Odor Exposure Increases the Number of Newborn Neurons in the Adult Olfactory Bulb and Improves Odor Memory

2002 • 662 citations

Short‐term and long‐term survival of new neurons in the rat dentate gyrus

2003 • 616 citations

Evidence for neurogenesis in the adult mammalian substantia nigra

2003 • 577 citations

3H-thymidine-radiographic studies of neurogenesis in the rat olfactory bulb

1983 • 501 citations

Neuropathology in mice expressing human alpha-synuclein.

2000 • 499 citations

Analysis of neurogenesis and programmed cell death reveals a self-renewing capacity in the adult rat brain

2000 • 497 citations

Differential neuropathological alterations in transgenic mice expressing α‐synuclein from the platelet‐derived growth factor and Thy‐1 promoters

2002 • 460 citations

Neuropathology in Mice Expressing Human α-Synuclein

2000 • 456 citations

The Adult Substantia Nigra Contains Progenitor Cells with Neurogenic Potential

2002 • 443 citations

Three‐dimensional counting: An accurate and direct method to estimate numbers of cells in sectioned material

1988 • 437 citations

Axon pathology in Parkinson’s disease and Lewy body dementia hippocampus contains α-, β-, and γ-synuclein

1999 • 417 citations

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders.

1998 • 403 citations

Long‐term survival and cell death of newly generated neurons in the adult rat olfactory bulb

2002 • 394 citations

Olfactory dysfunction in Parkinson's disease.

1997 • 389 citations

A nuclear antigen associated with cell proliferation and blast transformation.

1981 • 333 citations

X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats

2000 • 302 citations

Is it all DNA repair?

2002 • 294 citations

Subclinical dopaminergic dysfunction in asymptomatic Parkinson's disease patients' relatives with a decreased sense of smell

2001 • 289 citations

Inhibition of Dentate Granule Cell Neurogenesis with Brain Irradiation Does Not Prevent Seizure-Induced Mossy Fiber Synaptic Reorganization in the Rat

1999 • 288 citations

Lack of Nigral Pathology in Transgenic Mice Expressing Human α-Synuclein Driven by the Tyrosine Hydroxylase Promoter

2001 • 279 citations

Enhanced neurogenesis after transient global ischemia in the dentate gyrus of the rat

2001 • 245 citations

Population dynamics of adult‐formed granule neurons of the rat olfactory bulb

1985 • 199 citations

Young neurons from the adult subependymal zone proliferate and migrate along an astrocyte, extracellular matrix-rich pathway

1996 • 178 citations

Expression Pattern of Synucleins (Non‐Aβ Component of Alzheimer's Disease Amyloid Precursor Protein/α‐Synuclein) During Murine Brain Development

1998 • 169 citations

Odor deprivation leads to reduced neurogenesis and reduced neuronal survival in the olfactory bulb of the adult mouse

1994 • 167 citations

Dopaminergic and gabaergic interneurons of the olfactory bulb are derived from the neonatal subventricular zone

1996 • 144 citations

Differential localization of α-, β- and γ-synucleins in the rat CNS

2002 • 135 citations

Apoptosis in the subependyma of young adult rats after single and fractionated doses of X-rays.

1997 • 132 citations

Apoptosis is induced in the subependyma of young adult rats by ionizing irradiation

1996 • 97 citations

α-Synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease β-amyloid plaque cores

1999 • 91 citations

Cell death in the developing and sensory-deprived rat olfactory bulb

2001 • 91 citations

Profound astrogenesis in the striatum of adult mice following nigrostriatal dopaminergic lesion by repeated MPTP administration

2001 • 87 citations

Photoperiod–temperature and neuroblast proliferation–migration in the adult lizard cortex

1997 • 52 citations