α-Synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease β-amyloid plaque cores

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

1998 • 2,898 citations

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 • 1,589 citations

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

1998 • 1,546 citations

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.

1993 • 1,426 citations

The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

1995 • 1,266 citations

Identification of two distinct synucleins from human brain

1994 • 1,031 citations

Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

1998 • 949 citations

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

1998 • 756 citations

Nigral and Cortical Lewy Bodies and Dystrophic Nigral Neurites in Parkinsonʼs Disease and Cortical Lewy Body Disease Contain α-synuclein Immunoreactivity

1998 • 393 citations

NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease

1997 • 322 citations

Antibodies to ?-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease

1999 • 290 citations

Immunoelectron-microscopic demonstration of NACP/α-synuclein-epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies

1998 • 242 citations

Non-A.beta. Component of Alzheimer's Disease Amyloid (NAC) is Amyloidogenic

1995 • 232 citations

Characterization of the Precursor Protein of the Non-Aβ Component of Senile Plaques (NACP) in the Human Central Nervous System

1996 • 202 citations

NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.

1995 • 197 citations

Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's disease.

1996 • 166 citations

Alpha synuclein is present in Lewy bodies in sporadic Parkinson's disease

1998 • 131 citations

Novel α-Synuclein-Immunoreactive Proteins in Brain Samples from the Contursi Kindred, Parkinson's, and Alzheimer's Disease

1998 • 52 citations

Synuclein proteins and Alzheimer's disease

1994 • 47 citations

Reverse relationship between β-amyloid precursor protein and β-amyloid peptide plaques in Down's syndrome versus sporadic/familial Alzheimer's disease

1999 • 21 citations