Multiple signaling pathways in bovine chromaffin cells regulate tyrosine hydroxylase phosphorylation at Ser19, Ser31, and Ser40

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1991 • 1,901 citations

An Insulin-Stimulated Protein Kinase Similar to Yeast Kinases Involved in Cell Cycle Control

1990 • 701 citations

ACUTE REGULATION OF TYROSINE HYDROXYLASE BY NERVE ACTIVITY AND BY NEUROTRANSMITTERS VIA PHOSPHORYLATION

1989 • 487 citations

Adrenal medullary chromaffin cells in vitro

1984 • 325 citations

ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ.

1992 • 263 citations

Identification of four phosphorylation sites in the N-terminal region of tyrosine hydroxylase.

1986 • 243 citations

Phosphorylation of tyrosine hydroxylase in situ at serine 8, 19, 31, and 40.

1990 • 224 citations

Bovine adrenal chromaffin cells: high-yield purification and viability in suspension culture

1983 • 178 citations

Tyrosine hydroxylase in rat brain dopaminergic nerve terminals. Multiple-site phosphorylation in vivo and in synaptosomes.

1991 • 155 citations

Phosphorylation of tyrosine hydroxylase by calmodulin-dependent multiprotein kinase.

1984 • 152 citations

ERKs, extracellular signal-regulated MAP-2 kinases

1991 • 145 citations

A 42-kD tyrosine kinase substrate linked to chromaffin cell secretion exhibits an associated MAP kinase activity and is highly related to a 42-kD mitogen-stimulated protein in fibroblasts.

1990 • 142 citations

In Vitro Methods For Studying Secretion

1987 • 117 citations

Reduction of sulfoxides in peptides and proteins

1979 • 113 citations

Stimulation of Formation of Inositol Phosphates in Primary Cultures of Bovine Adrenal Chromaffin Cells by Angiotensin II, Histamine, Bradykinin, and Carbachol

1988 • 109 citations

Identification of protein phosphatase 2A as the major tyrosine hydroxylase phosphatase in adrenal medulla and corpus striatum: evidence from the effects of okadaic acid

1989 • 103 citations

Vasoactive intestinal polypeptide and muscarine mobilize intracellular Ca2+ through breakdown of phosphoinositides to induce catecholamine secretion. Role of IP3 in exocytosis.

1988 • 103 citations

Activation and Multiple‐Site Phosphorylation of Tyrosine Hydroxylase in Perfused Rat Adrenal Glands

1992 • 101 citations

Multiple site phosphorylation of tyrosine hydroxylase. Differential regulation in situ by a 8-bromo-cAMP and acetylcholine.

1982 • 100 citations

Prostaglandin E receptors in bovine adrenal medulla are coupled to adenylate cyclase via Gi and to phosphoinositide metabolism in a pertussis toxin-insensitive manner

1989 • 97 citations

Different Patterns of Agonist‐Stimulated Increases of ³H‐Inositol Phosphate Isomers and Cytosolic Ca²⁺ in Bovine Adrenal Chromaffin Cells: Comparison of the Effects of Histamine and Angiotensin II

1990 • 80 citations

Phosphorylation of human recombinant tyrosine hydroxylase isoforms 1 and 2: an additional phosphorylated residue in isoform 2, generated through alternative splicing.

1991 • 80 citations

Phosphorylation of pro-adrenocorticotropin/endorphin-derived peptides.

1982 • 79 citations

Nerve growth factor-mediated induction of tyrosine hydroxylase and of neurite outgrowth in cultures of bovine adrenal chromaffin cells: Dependence on developmental stage

1982 • 76 citations

Stimulation by ATP of Inositol Trisphosphate Accumulation and Calcium Mobilization in Cultured Adrenal Chromaffin Cells

1989 • 67 citations

Phosphorylation of bovine adrenal chromaffin cell tyrosine hydroxylase. Temporal correlation of acetylcholine's effect on site phosphorylation, enzyme activation, and catecholamine synthesis.

1988 • 67 citations

Stimulation-Dependent phosphorylation of tyrosine hydroxylase in rat corpus striatum

1987 • 61 citations

Non‐cholinergic component of rat splanchnic nerves predominates at low neuronal activity and is eliminated by naloxone.

1987 • 61 citations

Different effects on activity caused by phosphorylation of tyrosine hydroxylase at serine 40 by three multifunctional protein kinases

1991 • 58 citations

The peptide VIP is a neurotransmitter in rat adrenal medulla: physiological role in controlling catecholamine secretion.

1991 • 57 citations

Identification of an Activator of the Microtubule‐Associated Protein 2 Kinases ERK1 and ERK2 in PC12 Cells Stimulated with Nerve Growth Factor or Bradykinin

1992 • 57 citations

Vasoactive Intestinal Peptide Stimulates Catecholamine Biosynthesis in Isolated Adrenal Chromaffin Cells: Evidence for a Cyclic AMP‐Dependent Phosphorylation and Activation of Tyrosine Hydroxylase

1991 • 56 citations

Changes in Inositol 1,4,5‐Trisphosphate and Inositol 1,3,4,5‐Tetrakisphosphate Mass Accumulations in Cultured Adrenal Chromaffin Cells in Response to Bradykinin and Histamine

1991 • 53 citations

Isolation and nucleotide sequence of a cDNA clone encoding bovine adrenal tyrosine hydroxylase: Comparative analysis of tyrosine hydroxylase gene products

1988 • 51 citations

Vasoactive intestinal peptide elevates cyclic Amp levels and potentiates secretion in bovine adrenal chromaffin cells

1988 • 51 citations

Protein/Peptide Sequence Analysis: Current Methodologies

2018 • 49 citations

Effects of phorbol ester on tyrosine hydroxylase phosphorylation and activation in cultured bovine adrenal chromaffin cells.

1986 • 48 citations

Cholinergic regulation of protein phosphorylation in bovine adrenal chromaffin cells.

1988 • 48 citations

Quantitation of tyrosine hydroxylase protein levels: Spot immunolabeling with an affinity-purified antibody

1989 • 46 citations

In Vitro Phosphorylation of Bovine Adrenal Chromaffin Cell Tyrosine Hydroxylase by Endogenous Protein Kinases

1989 • 39 citations

Catecholamine secretion by perfused bovine adrenal medulla in response to nicotinic activation is inhibited by muscarinic receptors

1983 • 33 citations

Phosphorylation of tyrosine hydroxylase in protein kinase C-deficient PC12 cells

1989 • 29 citations

Stimulation by vasoactive intestinal polypeptide of catecholamine synthesis in isolated bovine adrenal chromaffin cells

1987 • 27 citations

Stimulus-responsive and rapid formation of inositol pentakisphosphate in cultured adrenal chromaffin cells.

1990 • 23 citations

Predicted Amino Acid Sequence of Bovine Tyrosine Hydroxylase and Its Similarity to Tyrosine Hydroxylases from Other Species

1988 • 21 citations

Nerve growth factor does not activate Na⁺/H⁺ exchange in PC12 pheochromocytoma cells

1985 • 20 citations

Both Short‐ and Long‐Term Effects of Nerve Growth Factor on Tyrosine Hydroxylase in Calf Adrenal Chromaffin Cells Are Blocked by S‐Adenosylhomocysteine Hydrolase Inhibitors

1987 • 19 citations

In situ phosphorylation of tyrosine hydroxylase in chromaffin cells: Localization to soluble compartments

1985 • 16 citations

Involvement of phosphoinositide metabolism in GABA-induced catecholamine release from cultured bovine adrenal chromaffin cells

1990 • 6 citations

The Adrenal Medulla 1986 - 1988

2017 • 3 citations