Interdependent action of RalGEF and Erk in Ras-induced primitive endoderm differentiation of F9 embryonal carcinoma cells

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

1995 • 2,723 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1).

1978 • 1,303 citations

Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras

1997 • 1,064 citations

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1994 • 1,012 citations

Multiple ras functions can contribute to mammalian cell transformation

1995 • 658 citations

Mammalian Grb2 Regulates Multiple Steps in Embryonic Development and Malignant Transformation

1998 • 377 citations

Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation

1998 • 341 citations

Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation.

1996 • 335 citations

A Role for the Ral Guanine Nucleotide Dissociation Stimulator in Mediating Ras-induced Transformation

1996 • 245 citations

Reactivity of monoclonal antibodies against intermediate filament proteins during embryonic development.

1981 • 233 citations

Evidence for a Ras/Ral signaling cascade

1996 • 214 citations

Stimulation of gene induction and cell growth by the Ras effector Rlf

1997 • 167 citations

Rapid Phosphorylation of Ets-2 Accompanies Mitogen-Activated Protein Kinase Activation and the Induction of Heparin-Binding Epidermal Growth Factor Gene Expression by Oncogenic Raf-1

1997 • 162 citations

Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1).

1994 • 128 citations

Reactivity of monoclonal antibodies against intermediate filament proteins during embryonic development

1981 • 122 citations

Parathyroid hormone inhibits mitogen-activated protein kinase activation in osteosarcoma cells via a protein kinase A-dependent pathway.

1995 • 80 citations

RalGDS Functions in Ras- and cAMP-mediated Growth Stimulation

1997 • 72 citations

Differentiation of F9 embryonal carcinoma cells induced by the c-jun and activated c-Ha-ras oncogenes.

1990 • 69 citations

Synergistic activation of c-fos promoter activity by Raf and Ral GDP dissociation stimulator

1997 • 63 citations

The Ras/Erk Pathway Induces Primitive Endoderm but Prevents Parietal Endoderm Differentiation of F9 Embryonal Carcinoma Cells

1999 • 54 citations