The therapeutic significance of concomitant antitumor immunity

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views.

1980 • 574 citations

Endotoxin and Double Stranded RNA render Macrophages Cytotoxic

1971 • 448 citations

MACROPHAGES IN SYNGENEIC ANIMAL TUMOURS

1972 • 295 citations

Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells.

1984 • 249 citations

A review of the influence of bacterial infection and of bacterial products (Coley's toxins) on malignant tumors in man; a critical analysis of 30 inoperable cases treated by Coley's mixed toxins, in which diagnosis was confirmed by microscopic examination selected for special study.

1953 • 244 citations

"Anomalous" THY-1(+) killer cells in allogeneic and F1-anti-parental mixed leukocyte culture. Relation to natural killer cells and allospecific cytotoxic T lymphocytes

1982 • 237 citations

Cells mediating graft rejection in the mouse. I. Lyt-1 cells mediate skin graft rejection.

1981 • 211 citations

Functional characterization of a stable, noncytolytic stage of macrophage activation in tumors.

1977 • 187 citations

Concomitant Tumor Immunity and the Resistance to a Second Tumor Challenge

1983 • 139 citations

WHICH T CELLS CAUSE GRAFT REJECTION?

1982 • 134 citations

Chemical Treatment of Tumors. IX. Reactions of Mice with Primary Subcutaneous Tumors to Injection of a Hemorrhage-Producing Bacterial Polysaccharide<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1944 • 133 citations

Expression of passively transferred immunity against an established tumor depends on generation of cytolytic T cells in recipient. Inhibition by suppressor T cells.

1983 • 123 citations

The immunological basis of endotoxin-induced tumor regression. Requirement for T-cell-mediated immunity.

1978 • 111 citations

?-Irradiation facilitates the expression of adoptive immunity against established tumors by eliminating suppressor T cells

1984 • 92 citations

The immunological basis of endotoxin-induced tumor regression. Requirement for a pre-existing state of concomitant anti-tumor immunity.

1978 • 83 citations

Concomitant immunity and specific depression of immunity by residual or reinjected syngeneic tumor tissue.

1971 • 73 citations

Precursor frequency analysis of lymphokine-secreting alloreactive T lymphocytes. Dissociation of subsets producing interleukin 2, macrophage-activating factor, and granulocyte-macrophage colony-stimulating factor on the basis of Lyt-2 phenotype.

1982 • 72 citations

Cloned LYT-2+ cytolytic T lymphocytes destroy allogeneic tissue in vivo.

1984 • 69 citations

T cell-mediated immunity to oncornavirus-induced tumors. II. Ability of different T cell sets to prevent tumor growth in vivo.

1980 • 63 citations

Mechanisms of anti-tumor action of Corynebacterium parvum. II. Potentiated cytolytic T cell response and its tumor-induced suppression.

1981 • 40 citations

"Anomalous" Thy-1+ killer cells in allogeneic and F1-anti-parental mixed leukocyte culture. Relation to natural killer cells and allospecific cytotoxic T lymphocytes.

1983 • 39 citations

In vitro induction of tumor-specific immunity. IV. Specific adoptive immunotherapy with cytotoxic T cells induced in vitro to plasmacytoma antigens

1977 • 38 citations

CELLS MEDIATING GRAFT REJECTION IN THE MOUSE II. THE LY PHENOTYPES OF CELLS PRODUCING TUMOR ALLOGRAFT REJECTION

1982 • 31 citations

ADOPTIVE IMMUNIZATION AGAINST AN ESTABLISHED TUMOR WITH CYTOLYTIC VERSUS MEMORY T CELLS

1984 • 31 citations

Functional activity in vivo of effector T cell populations. I. Antitumor activity exhibited by allogeneic mixed leukocyte culture cells.

1982 • 30 citations

The therapeutic significance of concomitant antitumor immunity

1984 • 27 citations

The in vivo activity of in vitro immunized mouse thymocytes. II. Rejection of skin allografts and graft-vs-host activity.

1972 • 27 citations

Modulation of antitumor immunity ? Immunobiologic approaches

1982 • 25 citations

In vivo and in vitro antitumor activity expressed by cells of concomitantly immune mice.

1983 • 13 citations

Thymus-dependent response: too little and too late for immunosurveillance.

1982 • 7 citations