Precursor frequency analysis of lymphokine-secreting alloreactive T lymphocytes. Dissociation of subsets producing interleukin 2, macrophage-activating factor, and granulocyte-macrophage colony-stimulating factor on the basis of Lyt-2 phenotype.

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

1981 • 1,281 citations

T cell growth factor receptors. Quantitation, specificity, and biological relevance

1981 • 1,087 citations

T‐Cell Growth Factor

1980 • 917 citations

Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly+ cells in the generation of killer activity.

1975 • 758 citations

T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views.

1980 • 574 citations

Replacement of T-Cell Function by a T-Cell Product

1972 • 537 citations

The nature and action of granulocyte-macrophage colony stimulating factors

1980 • 526 citations

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO

1974 • 488 citations

Thymoma production of T cell growth factor (Interleukin 2).

1980 • 487 citations

Limiting dilution assays for the determination of immunocompetent cell frequencies.

1981 • 386 citations

Significance of Lyt phenotypes: Lyt2 antibodies block activities of T cells that recognize class 1 major histocompatibility complex antigens regardless of their function.

1981 • 234 citations

Quantitation and Cloning of Cytolytic T Lymphocytes and their Precursors

1980 • 213 citations

Production of Colony-Stimulating Factor in Mitogen-Stimulated Lymphocyte Cultures

1974 • 213 citations

Generation of cytolytic T lymphocytes in vitro. IX. induction of secondary CTL responses in primary long-term MLC by supernatants from secondary MLC.

1978 • 166 citations

Production of macrophage-activating factor by T lymphocyte clones and correlation with other lymphokine activities.

1982 • 142 citations

Studies on the activation of mouse bone marrow‐derived macrophages by the macrophage cytotoxicity factor (MCF)

1976 • 138 citations

Macrophage Activation for Tumor Cytotoxicity: Increased Lymphokine Responsiveness of Peritoneal Macrophages During Acute Inflammation

1978 • 137 citations

Limiting dilution analysis of alloantigen-reactive T lymphocytes. I. Comparison of precursor frequencies for proliferative and cytolytic responses.

1979 • 132 citations

An Lyt differentiated thymocyte subpopulation detected by flow microfluorometry

1979 • 122 citations

Biology of the Lymphokines

2013 • 118 citations

Phenotypic and functional properties of murine thymocytes. I. Precursors of cytolytic T lymphocytes and interleukin 2-producing cells are all contained within a subpopulation of "mature" thymocytes as analyzed by monoclonal antibodies and flow microfluorometry

1982 • 114 citations

The role of interleukin-2 (IL-2) in the differentiatin of cytotoxic T cells: the effect of monoclonal anti-IL-2 antibody and absorption with IL-2 dependent T cell lines.

1981 • 113 citations

T-cell lines which cooperate in generation of specific cytolytic activity

1979 • 105 citations

Multiple biologic activities of a cloned inducer T-cell population.

1981 • 90 citations

Macrophage cytotoxicity factor. A product of in vitro sensitized thymus‐dependent cells

1973 • 83 citations

Enumeration of IL 2-secreting helper T cells by limiting dilution analysis, and demonstration of unexpectedly high levels of IL 2 production per responding cell.

1982 • 77 citations

Alloreactive cloned T cell lines. V. Differential kinetics of IL 2, CSF, and BCSF release by a cloned T amplifier cell and its variant.

1981 • 58 citations

Biologic properties of chromatographically separated murine thymoma-derived Interleukin 2 and colony-stimulating factor.

1981 • 55 citations

Enumeration of alloreactive helper T lymphocytes which cooperate with cytolytic T lymphocytes

1981 • 42 citations

Interleukin 2 Production by Both Ly2⁺ and Ly2⁻ T‐Cell Subsets

1981 • 35 citations

T-T cell interactions during in vitro cytotoxic T lymphocyte responses. V. Precursor frequencies and specificity of alloreactive helper T cells.

1982 • 32 citations

Limiting dilution analysis of alloantigen-reactive T lymphocytes. V. Lyt phenotype of cytolytic T lymphocyte precursors reactive against normal and mutant H-2 antigens.

1981 • 31 citations

Production of interferon in the murine mixed lymphocyte culture. II. Interferon production is a T cell‐dependent function, independent of proliferation

1979 • 30 citations

The use of a clonal assay for cytotoxic T lymphocytes to determine the Ly phenotypes of the cytotoxic precursor and effector cells to alloantigens and trinitrophenyl-modified self antigens.

1980 • 23 citations

Heterogeneity of soluble T cell products I. Precursor frequency and correlation analysis of cytotoxic and immune interferon (IFN‐γ)‐producing spleen cells in the mouse

1982 • 15 citations

Use of positively selected Lyt-2+ mouse splenocytes to examine interleukin-2 secretion in responses to alloantigens and to TNP-modified syngeneic cells

1982 • 14 citations

Cell surface phenotype of cytolytic T lymphocyte precursors in aged nude mice

1981 • 10 citations

Enumeration of haemopoietic progenitors (CFU-C and BFU-E) in liquid microculture using a limiting dilution analysis.

1980 • 5 citations