Advances in Chemotherapy for Brain Tumors

Response criteria for phase II studies of supratentorial malignant glioma.

1990 • 2,401 citations

Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas

1978 • 1,663 citations

Randomized Comparisons of Radiotherapy and Nitrosoureas for the Treatment of Malignant Glioma after Surgery

1980 • 1,625 citations

Cancer statistics, 1994

1994 • 1,345 citations

Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults

1993 • 872 citations

Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint radiation therapy oncology group and eastern cooperative oncology group study

1983 • 600 citations

The treatment of medulloblastoma

1990 • 584 citations

Combined modality therapy for primary CNS lymphoma.

1992 • 543 citations

Neurosurgical management of low-grade astrocytoma of the cerebral hemispheres

1984 • 524 citations

Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas

1991 • 485 citations

Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856)

1992 • 483 citations

Randomized trial of three chemotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma

1989 • 455 citations

Adjuvant chemotherapy for medulloblastoma: The first multi-centre control trial of the International Society of Paediatric Oncology (SIOP I)

1990 • 400 citations

Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarrazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report

1990 • 399 citations

Primary Central Nervous System Lymphoma

1993 • 394 citations

Increasing incidence of primary brain lymphoma in the US

1988 • 392 citations

Primary CNS lymphoma treated with osmotic blood-brain barrier disruption: prolonged survival and preservation of cognitive function.

1991 • 379 citations

Successful chemotherapy for recurrent malignant oligodendroglioma

1988 • 346 citations

Necrosis as a prognostic criterion in malignant supratentorial, astrocytic gliomas

1983 • 282 citations

Temozolomide: A new oral cytotoxic chemotherapeutic agent with promising activity against primary brain tumours

1993 • 276 citations

Radiation treatment for medulloblastoma

1981 • 255 citations

A randomized comparison of intra-arterial versus intravenous with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma

1992 • 241 citations

Improved survival with the use of adjuvant chemotherapy in the treatment of medulloblastoma

1991 • 229 citations

Neoadjuvant chemotherapy for newly diagnosed germ-cell tumors of the central nervous system

1987 • 216 citations

Criteria for evaluating patients undergoing chemotherapy for malignant brain tumors

1977 • 201 citations

The treatment of oligodendrogliomas and mixed oligodendroglioma-astrocytomas with PCV chemotherapy

1992 • 187 citations

Intravenous carboplatin for recurrent malignant glioma: a phase II study.

1991 • 173 citations

Therapeutic Efficacy of Multiagent Chemotherapy with Drug Delivery Enhancement by Blood-Brain Barrier Modification in Glioblastoma

1986 • 166 citations

High-dose cyclophosphamide chemotherapy for recurrent CNS tumors in children

1981 • 164 citations

Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors

1994 • 158 citations

High-dose methotrexate for non-AIDS primary central nervous system lymphoma

1989 • 154 citations

Intracarotid infusion of cis-diamminedichloroplatinum in the treatment of recurrent malignant brain tumors

1984 • 136 citations

The basis for current treatment recommendations for malignant gliomas

1994 • 135 citations

Survival and prognosis of patients with astrocytoma with atypical or anaplastic features

1985 • 126 citations

Opening the blood–brain and blood–tumor barriers in experimental rat brain tumors: The effect of intracarotid hyperosmolar mannitol on capillary permeability and blood flow

1986 • 126 citations

Osmotic blood-brain barrier disruption and chemotherapy in the treatment of high grade malignant glioma: patient series and literature review

1992 • 123 citations

Single-Agent Chemotherapy of Brain Tumors

1976 • 110 citations

Combined‐modality therapy in the treatment of primary central nervous system lymphoma in AIDS

1994 • 109 citations

Chloroethyl-cyclohexyl-nitrosourea (CCNU) in the treatment of malignant brain tumors

1973 • 108 citations

The rationale and methodology for intra-arterial chemotherapy with BCNU as treatment for glioblastoma

1985 • 106 citations

High-dose BCNU with autologous bone marrow rescue for recurrent glioblastoma multiforme

1981 • 102 citations

Carboplatin and etoposide chemotherapy regimen for recurrent malignant glioma: a phase II study.

1992 • 97 citations

Procarbazine hydrochloride in the treatment of brain tumors

1974 • 96 citations

Current management of primary central nervous system lymphoma.

1995 • 94 citations

The Treatment of Anaplastic Oligodendrogliomas and Mixed Gliomas

1993 • 94 citations

Treatment of Malignant Glioma

1976 • 93 citations

Intravenous recombinant interferon beta in patients with recurrent malignant gliomas: a phase I/II study.

1991 • 89 citations

Phase II study of procarbazine, CCNU, and vincristine combination chemotherapy in the treatment of malignant brain tumors

1975 • 88 citations

Intracarotid cisplatin chemotherapy for recurrent gliomas

1989 • 88 citations

Evaluation of CCNU, VM-26 plus CCNU, and procarbazine in supratentorial brain gliomas

1981 • 85 citations

Intensive 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) monochemotherapy and autologous marrow transplantation for malignant glioma.

1986 • 84 citations

Treatment of patients with recurrent gliomas with cyclophosphamide and vincristine

1990 • 80 citations

The chemotherapy of high-grade astrocytomas.

1994 • 78 citations

Effect of CCNU on survival rate of objective remission and duration of free interval in patients with malignant brain glioma—Final evaluation

1978 • 77 citations

Randomised, controlled study of intratumoral recombinant γ-interferon treatment in newly diagnosed glioblastoma

1994 • 73 citations

The therapy of primary brain lymphoma

1991 • 73 citations

Interstitial chemotherapy for brain tumors: review

1991 • 72 citations

Procarbazine chemotherapy in the treatment of recurrent malignant astrocytomas after radiation and nitrosourea failure

1990 • 72 citations

Phase II study of cisplatin in recurrent astrocytomas in adults: A southwest oncology group study

1983 • 68 citations

Treatment of recurrent gliomas and metastatic brain tumors with a polydrug protocol designed to combat nitrosourea resistance.

1992 • 67 citations

Neuro-oncology index and review (adult primary brain tumors)

1991 • 65 citations

Primary central nervous system lymphoma: a role for adjuvant chemotherapy

1992 • 64 citations

Prolongation of survival for high-grade malignant gliomas with adjuvant high-dose BCNU and autologous bone marrow transplantation.

1987 • 59 citations

Controversies in the Management of Intracranial Germ Cell Tumors

1991 • 59 citations

Improvement in survival produced by sequential therapies in the treatment of recurrent medulloblastoma

1983 • 56 citations

High dose BCNU chemotherapy with autologous bone marrow transplantation and full dose radiotherapy for grade IV astrocytoma

1988 • 52 citations

Evaluation of prognostic factors in chemotherapy of recurrent brain tumors.

1983 • 47 citations

Intrathecal Chemotherapy for Leptomeningeal Dissemination of Medulloblastoma

1981 • 43 citations

Immunotherapy of malignant gliomas.

1994 • 38 citations

High-dose carmustine with autologous bone marrow transplantation for the adjuvant treatment of high-grade gliomas of the central nervous system.

1987 • 37 citations

PCNU treatment for recurrent malignant gliomas.

1984 • 33 citations

Autologous bone marrow transplantation

1991 • 30 citations

Phase II evaluation of dibromodulcitol in the treatment of recurrent medulloblastoma, ependymoma, and malignant astrocytoma

1984 • 30 citations

Intra-arterial mannitol infusion in the chemotherapy for malignant brain tumors

1993 • 27 citations

The chemotherapy of adult primary brain tumors

1993 • 26 citations

The management of malignant gliomas with radiation therapy: Therapeutic results and research strategies

1991 • 25 citations

Combined Intra-arterial and Systemic Chemotherapy for Recurrent Malignant Brain Tumors

1992 • 24 citations

A phase I/II study of 24 hour intravenous AZQ in recurrent primary brain tumors

1988 • 22 citations

BCNU (NSC-409962) and procarbazine (NSC-77213) treatment for malignant brain tumors.

1976 • 21 citations

Intravenous BCNU and AZQ in patients with recurrent malignant gliomas

1989 • 20 citations

Astrocytomas: Diagnosis, treatment and biology

1993 • 19 citations

Comparison of postoperative irradiation alone and in combination with BCNU (NSC-409962) in the management of malignant gliomas.

1974 • 16 citations

5 GLIOBLASTOMA MULTIFORME AND ANAPLASTIC ASTROCYTOMA

1983 • 15 citations

Chemotherapy and immunotherapy in adult malignant gliomas

1993 • 14 citations

A phase II evaluation of human lymphoblastoid interferon (Wellferon) in relapsed high grade malignant glioma

1993 • 12 citations

[Clinical application of a sustained release anticancer pellet].

1985 • 7 citations