Temozolomide: A new oral cytotoxic chemotherapeutic agent with promising activity against primary brain tumours

Response criteria for phase II studies of supratentorial malignant glioma.

1990 • 2,401 citations

Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas

1978 • 1,663 citations

Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856)

1992 • 483 citations

Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine.

1987 • 386 citations

The role of chemotherapy in the treatment of gliomas in adults

1989 • 51 citations

A randomized study of CCNU with and without benznidazole in the treatment of recurrent grades 3 and 4 astrocytoma

1989 • 24 citations

Does chemotherapy benefit the patient with a central nervous system glioma?

1987 • 22 citations

Studies on high grade cerebral gliomas

1990 • 20 citations

Effect of HECNU in malignant supratentorial gliomas ? a phase II study

1988 • 9 citations