Estradiol reverses TGF-β1-stimulated type IV collagen gene transcription in murine mesangial cells

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Functional Analysis of the Transforming Growth Factor βResponsive Elements in the WAF1/Cip1/p21 Promoter

1995 • 440 citations

The impact of gender on the progression of chronic renal disease

1995 • 386 citations

Transforming growth factor-β regulates production of proteoglycans by mesangial cells

1990 • 365 citations

Angiotensin II stimulates the proliferation and biosynthesis of type I collagen in cultured murine mesangial cells.

1992 • 332 citations

Transforming growth factor-beta stimulates alpha 2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site.

1994 • 311 citations

Transforming Growth Factor β Activates the Promoter of Cyclin-dependent Kinase Inhibitor p15 through an Sp1 Consensus Site

1995 • 249 citations

Estrogen receptor-Sp1 complexes mediate estrogen-induced cathepsin D gene expression in MCF-7 human breast cancer cells.

1994 • 247 citations

Age-dependent glomerular damage in the rat. Dissociation between glomerular injury and both glomerular hypertension and hypertrophy. Male gender as a primary risk factor.

1994 • 235 citations

Activation and attenuation of transcription factor NF-kB in mouse glomerular mesangial cells in response to tumor necrosis factor-alpha, immunoglobulin G, and adenosine 3':5'-cyclic monophosphate. Evidence for involvement of reactive oxygen species.

1994 • 179 citations

Functional analysis of human alpha 1(I) procollagen gene promoter. Differential activity in collagen-producing and -nonproducing cells and response to transforming growth factor beta 1.

1994 • 158 citations

Alpha 1(IV) and alpha 2(IV) collagen genes are regulated by a bidirectional promoter and a shared enhancer.

1988 • 139 citations

Effects of sex hormones on mesangial cell proliferation and collagen synthesis

1996 • 137 citations

Overlapping Pathways Mediate the Opposing Actions of Tumor Necrosis Factor-α and Transforming Growth Factor-β on α2(I) Collagen Gene Transcription

1995 • 110 citations

Nonenzymatic glycation of mesangial matrix and prolonged exposure of mesangial matrix to elevated glucose reduces collagen synthesis and proteoglycan charge

1993 • 98 citations

Transforming growth factor-beta and the glomerular extracellular matrix in renal pathology.

1994 • 96 citations

PKC and high glucose stimulate collagen alpha 1 (IV) transcriptional activity in a reporter mesangial cell line

1994 • 88 citations

Characterization of the promoter for the alpha 1 (IV) collagen gene. DNA sequences within the first intron enhance transcription.

1988 • 61 citations

Serum-stimulated α₁type IV collagen gene transcription is mediated by TGF-β and inhibited by estradiol

1998 • 60 citations

Matrix protein synthesis by glomerular mesangial cells in culture: Effects of transforming growth factor β (TGFβ) and platelet‐derived growth factor (PDGF) on fibronectin and collagen type IV mRNA

1995 • 56 citations

Effects of sex hormones on mesangial cells

1995 • 53 citations

Transcriptional activation of matrix genes by transforming growth factor beta 1 in mesangial cells.

1993 • 52 citations

Differential effects of DNA-binding proteins on bidirectional transcription from the common promoter region of human collagen type IV genes COL4A1 and COL4A2

1993 • 41 citations

A novel sequence in the type IV collagen promoter binds nuclear proteins from Engelbreth-Holm-Swarm tumor.

1992 • 27 citations

Recombinant activation domains of virion protein 16 and human estrogen receptor generate transcriptional interference in vitro by distinct mechanisms.

1993 • 15 citations

Transforming growth factor-beta modulation of the alpha 1(IV) collagen gene in murine proximal tubular cells

1996 • 14 citations