A new PET ligand for the dopamine transporter: studies in the human brain.

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Graphical Analysis of Reversible Radioligand Binding from Time—Activity Measurements Applied to [N-¹¹C-Methyl]-(−)-Cocaine PET Studies in Human Subjects

1990 • 1,412 citations

Imaging Dopamine Receptors in the Human Brain by Positron Tomography

1983 • 743 citations

Dopamine visualized in the basal ganglia of living man

1983 • 643 citations

Imaging endogenous dopamine competition with [¹¹C]raclopride in the human brain

1994 • 378 citations

Striatal binding of the PET ligand ¹¹C‐raclopride is altered by drugs that modify synaptic dopamine levels

1993 • 285 citations

Quantification of Neuroreceptors in the Living Human Brain. I. Irreversible Binding of Ligands

1986 • 279 citations

PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride

1987 • 279 citations

Effects of cocaine and related drugs in nonhuman primates. I. [3H]cocaine binding sites in caudate-putamen.

1989 • 236 citations

In vivo imaging of baboon and human dopamine transporters by positron emission tomography using [¹¹C]WIN 35,428

1993 • 178 citations

In vivoevaluation of striatal dopamine reuptake sites using 11C-nomifensine and positron emission tomography

1987 • 146 citations

Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6.

1991 • 125 citations

Sleep apnea, narcolepsy, and dreaming: Regional cerebral hemodynamics

1980 • 80 citations

In vivo quantitative imaging of dopamine receptors in human brain using positron emission tomography and [76Br]bromospiperone

1985 • 77 citations

In Vivo Imaging of Vesicular Monoamine Transporters in Human Brain Using [¹¹C]Tetrabenazine and Positron Emission Tomography

1993 • 67 citations

4‐[¹⁸F]Fluoro‐L‐m‐Tyrosine: An L‐3,4‐Dihydroxyphenylalanine Analog for Probing Presynaptic Dopaminergic Function with Positron Emission Tomography

1989 • 60 citations

In vivo binding of [18F]GBR 13119 to the brain dopamine uptake system

1988 • 45 citations

Synthesis of the racemate and individual enantiomers of [11C]methylphenidate for studying presynaptic dopaminergic neuron with positron emission tomography

1994 • 33 citations

Sensitivity of striatal [¹¹C]cocaine binding to decreases in synaptic dopamine

1995 • 33 citations

Mapping brain neuroleptic receptors in the live baboon.

1984 • 28 citations

Preparation of a potential positron emission tomographic radioligand for the dopamine transporter

1994 • 12 citations

Synthesis and evaluation of the racemate and individual enantiomers of C-11 labeled methylphenidate as radioligands for the presynaptic dopaminergic neuron

1994 • 1 citations