Leptin induction of UCP1 gene expression is dependent on sympathetic innervation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

1995 • 4,457 citations

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 • 4,057 citations

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

1995 • 3,302 citations

Abnormal splicing of the leptin receptor in diabetic mice

1996 • 2,361 citations

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

1997 • 1,647 citations

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

1997 • 1,334 citations

Receptor-mediated regional sympathetic nerve activation by leptin.

1997 • 980 citations

UCP3: An Uncoupling Protein Homologue Expressed Preferentially and Abundantly in Skeletal Muscle and Brown Adipose Tissue

1997 • 728 citations

Leptin increases uncoupling protein expression and energy expenditure

1997 • 396 citations

Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation

1997 • 384 citations

Direct effects of leptin on brown and white adipose tissue.

1997 • 377 citations

The nucleotide sequence of Saccharomyces cerevisiae chromosome VII

1997 • 298 citations

Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system

1995 • 293 citations

Mechanism and evolution of the uncoupling protein of brown adipose tissue

1990 • 270 citations

Tissue‐dependent upregulation of rat uncoupling protein‐2 expression in response to fasting or cold

1997 • 221 citations

Lipoprotein Lipase: Recent Contributions from Molecular Biology

1992 • 147 citations

The mitochondrial uncoupling protein gene. Correlation of exon structure to transmembrane domains.

1988 • 123 citations

Coexisting beta-adrenoceptor subtypes: significance for thermogenic process in brown fat cells

1994 • 114 citations

Differential adrenergic regulation of beta 1- and beta 3-adrenoreceptor messenger ribonucleic acids in adipose tissues.

1992 • 98 citations

Effects of agonist exposure on the coupling of beta 1 and beta 3 adrenergic receptors to adenylyl cyclase in isolated adipocytes.

1992 • 84 citations

beta 3-Adrenergic-mediated suppression of leptin gene expression in rats

1997 • 76 citations

Selective loss of uncoupling protein from mitochondria of surgically denervated brown adipose tissue of cold-acclimated mice

1986 • 66 citations

Differential effects of retinoic acid on uncoupling protein-1 and leptin gene expression

1998 • 60 citations

Thermogenesis and mitochondrial GDP binding with age in response to the novel agonist CGP-12177A

1992 • 52 citations

Thermoregulation with Age: Role of Thermogenesis and Uncoupling Protein Expression in Brown Adipose Tissue

1994 • 46 citations

Thermogenesis in brown adipose tissue with age: Post-receptor activation by forskolin

1996 • 32 citations

Beta-3 adrenoceptor (beta-3AR) expression in leptin treated Ob/Ob mice

1997 • 29 citations

Insulin and metabolic efficiency in rats. I. Effects of sucrose feeding and BAT axotomy

1986 • 18 citations

Is adrenergic innervation essential for maintenance of UCP in hamster BAT mitochondria?

1988 • 15 citations