Olfactory desensitization requires membrane targeting of receptor kinase mediated by beta gamma-subunits of heterotrimeric G proteins.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Structural chemistry and molecular biology

1968 • 1,698 citations

Turning off the signal: desensitization of β‐adrenergic receptor function

1990 • 1,241 citations

Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors

1992 • 703 citations

Radioimmunoassay for Cyclic Nucleotides

1972 • 582 citations

The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase.

1993 • 467 citations

β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family

1989 • 451 citations

Light-dependent phosphorylation of rhodopsin: number of phosphorylation sites

1982 • 441 citations

Rapid kinetics of second messenger formation in olfactory transduction

1990 • 438 citations

G protein—coupled receptor kinases

1993 • 434 citations

Different β-subunits determine G-protein interaction with transmembrane receptors

1992 • 390 citations

Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases

1992 • 306 citations

Role of phosphorylation in desensitization of the β-adrenoceptor

1990 • 300 citations

Receptor-effector coupling by G proteins: implications for normal and abnormal signal transduction

1992 • 290 citations

G-protein-coupled receptor kinases

1991 • 219 citations

Signaling pathways in odorant detection

1992 • 218 citations

Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family

1991 • 214 citations

Activation by G protein beta gamma subunits of agonist- or light-dependent phosphorylation of muscarinic acetylcholine receptors and rhodopsin.

1992 • 202 citations

β-Adrenergic Receptor Kinase-2 and β-Arrestin-2 as Mediators of Odorant-Induced Desensitization

1993 • 201 citations

The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain

1992 • 197 citations

Isoprenylation of a protein kinase. Requirement of farnesylation/alpha-carboxyl methylation for full enzymatic activity of rhodopsin kinase.

1992 • 196 citations

Termination of second messenger signaling in olfaction.

1992 • 168 citations

Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family.

1993 • 159 citations

A beta-adrenergic receptor kinase-like enzyme is involved in olfactory signal termination.

1993 • 146 citations

Second messenger signalling in olfaction

1992 • 109 citations

A partially purified preparation of isolated chemosensory cilia from the olfactory epithelium of the bullfrog, Rana catesbeiana

1986 • 107 citations

G-protein cascades: gain and kinetics

1992 • 104 citations

Activation by G protein beta gamma subunits of beta-adrenergic and muscarinic receptor kinase.

1993 • 83 citations

Mechanism of beta-adrenergic receptor kinase activation by G proteins

1993 • 83 citations

Dual regulation by G proteins of agonist‐dependent phosphorylation of muscarinic acetylcholine receptors

1990 • 80 citations

Odor-induced phosphorylation of olfactory cilia proteins.

1992 • 58 citations