Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

Fetal cells in the blood of pregnant women: detection and enrichment by fluorescence-activated cell sorting.

1979 • 438 citations

High-resolution chromosomal localization of human genes for amylase, proopiomelanocortin, somatostatin, and a DNA fragment (D3S1) by in situ hybridization.

1983 • 274 citations

Individual interphase chromosome domains revealed by in situ hybridization

1985 • 274 citations

Rabl's model of the interphase chromosome arrangement tested in Chinise hamster cells by premature chromosome condensation and laser-UV-microbeam experiments

1982 • 271 citations

Chromosome-specific organization of human alpha satellite DNA.

1985 • 265 citations

Isolation and characterization of an alphoid centromeric repeat family from the human Y chromosome

1985 • 236 citations

Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories

1985 • 231 citations

Sequence definition and organization of a human repeated DNA

1980 • 230 citations

2-Acetylaminofluorene-modified probes for the indirect hybridocytochemical detection of specific nucleic acid sequences

1984 • 208 citations

Two subsets of human alphoid repetitive DNA show distinct preferential localization in the pericentric regions of chromosomes 13, 18, and 21

1986 • 156 citations

Chromosome-specific subfamilies within human alphoid repetitive DNA

1986 • 127 citations

Cytologic evidence for three human X-chromosomal segments escaping inactivation

1983 • 108 citations

Detection of DNA Sequences in Nuclei in Suspension by in Situ Hybridization and Dual Beam Flow Cytometry

1985 • 92 citations

Sex chromosome positions in human interphase nuclei as studied by in situ hybridization with chromosome specific DNA probes

1984 • 83 citations

Sequence heterogeneity within the human alphoid repetitive DNA family

1986 • 80 citations

Sensitive detection of hybridocytochemical results by means of reflection-contrast microscopy.

1985 • 65 citations

Advances in human genetics. Vol. 1

1973 • 59 citations

Chromosomal Abnormalities in Leukemia and Lymphoma: Clinical and Biological Significance

1986 • 59 citations

A new hybridocytochemical method based on mercurated nucleic acid probes and sulfhydryl-hapten ligands

1986 • 55 citations

Medical genetics—Past, present, future

1985 • 29 citations

Gene mapping and physical arrangements of human chromatin in transformed, hybrid cells: Fluorescent and autoradiographic in situ hybridization compared

1986 • 24 citations

[Non-random position of homologous chromosomes (no. 9 and YY) in interphase nuclei of human fibroblasts (author's transl)].

1975 • 22 citations

Chromosome assignment of two cloned DNA probes hybridizing predominantly to human sex chromosomes

1984 • 21 citations

Nonrandom arrangement of human chromatin: topography of disomic markers X, Y, and 1h+

1973 • 21 citations

Nichtzufällige Verteilung homologer Chromosomen (Nr. 9 und YY) in Interphasekernen Menschlicher Fibroblasten

1975 • 15 citations

Somatic pairings of the Y heterochromatin in human XYY and XYqi cells

1981 • 14 citations

Two subsets of human alphoid repetitive DNA show distinct preferential localization in the pericentromeric heterochromatin of chromosomes 13, 21 and 18

1986 • 5 citations

The clinical significance of chromosomal changes in acute leukemia.

1985 • 3 citations