Heat shock protects L6 myotubes from catabolic effects of dexamethasone and prevents downregulation of NF-κB

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

Retention of differentiation potentialities during prolonged cultivation of myogenic cells.

1968 • 975 citations

Muscle Proteolysis Induced by a Circulating Peptide in Patients with Sepsis or Trauma

1983 • 469 citations

The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway.

1996 • 440 citations

THE IMMEDIATE CAUSES OF DEATH IN CANCER

1932 • 418 citations

Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis?

2000 • 389 citations

1 Progress and Perspectives on the Biology of Heat Shock Proteins and Molecular Chaperones

1994 • 342 citations

Glucocorticoids and muscle catabolism

1999 • 290 citations

Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle.

1997 • 264 citations

Sepsis stimulates nonlysosomal, energy-dependent proteolysis and increases ubiquitin mRNA levels in rat skeletal muscle.

1994 • 256 citations

Heat stress attenuates skeletal muscle atrophy in hindlimb-unweighted rats

2000 • 249 citations

Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids.

1996 • 249 citations

The expression of genes in the ubiquitin-proteasome proteolytic pathway is increased in skeletal muscle from patients with cancer

1999 • 192 citations

Sepsis stimulates release of myofilaments in skeletal muscle by a calcium‐dependent mechanism

1999 • 191 citations

Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats

1999 • 184 citations

Physiological hypercortisolemia increases proteolysis, glutamine, and alanine production

1988 • 165 citations

8. Stress-induced activation of the heat-shock response: cell and molecular biology of heat-shock factors

1999 • 154 citations

Stress response decreases NF-kappaB nuclear translocation and increases I-kappaBalpha expression in A549 cells.

1997 • 149 citations

Total and myofibrillar protein breakdown in different types of rat skeletal muscle: Effects of sepsis and regulation by insulin

1989 • 147 citations

Glucocorticoids Induce Proteasome C3 Subunit Expression in L6 Muscle Cells by Opposing the Suppression of Its Transcription by NF-κB

2000 • 143 citations

Human skeletal muscle HSP70 response to training in highly trained rowers

1999 • 141 citations

Increased protein degradation and decreased protein synthesis in skeletal muscle during cancer cachexia

1993 • 131 citations

The stress response and the lung

1997 • 131 citations

Current Concepts of Protein Turnover and Amino Acid Transport in Liver and Skeletal Muscle During Sepsis

1988 • 124 citations

Induction of heat shock protein 70 protects intestinal epithelial IEC-18 cells from oxidant and thermal injury

1996 • 112 citations

Blocking the Endogenous Increase in HSP 72 Increases Susceptibility to Hypoxia and Reoxygenation in Isolated Adult Feline Cardiocytes

1997 • 111 citations

DEXAMETHASONE STIMULATES PROTEASOME- AND CALCIUM-DEPENDENT PROTEOLYSIS IN CULTURED L6 MYOTUBES

1998 • 103 citations

Regulation of protein synthesis and degradation in L8 myotubes. Effects of serum, insulin and insulin-like growth factors

1989 • 100 citations

Burn injury stimulates multiple proteolytic pathways in skeletal muscle, including the ubiquitin-energy-dependent pathway.

1995 • 99 citations

Continuous contractile activity induces fiber type specific expression of HSP70 in skeletal muscle

1996 • 99 citations

Influence of burn injury on protein metabolism in different types of skeletal muscle and the role of glucocorticoids.

1995 • 89 citations

Effects of dexamethasone on protein degradation and protease gene expression in rat L8 myotube cultures

1995 • 88 citations

Nutrition and Cancer: Physiological Interrelationships

1985 • 86 citations

Effect of the glucocorticoid receptor antagonist RU 38486 on muscle protein breakdown in sepsis.

1991 • 75 citations

Induction of the Stress Response In Vivo Decreases Nuclear Factor–Kappa B Activity in Jejunal Mucosa of Endotoxemic Mice

2000 • 73 citations

Ubiquitin and proteasome gene expression is increased in skeletal muscle of slim AIDS patients.

1998 • 66 citations

Respiratory muscle injury in animal models and humans.

1998 • 59 citations

Protection against endotoxemia by HSP70 in rodent cardiomyocytes

2000 • 52 citations

Potential protective role of the heat shock response in sepsis.

1998 • 42 citations

Regulation of protein turnover by glutamine in heat-shocked skeletal myotubes

1997 • 37 citations

ACTIVATION OF NF-κB VARIES IN DIFFERENT REGIONS OF THE GASTROINTESTINAL TRACT DURING ENDOTOXEMIA

2000 • 37 citations

Pathways of muscle protein breakdown in injury and sepsis

1999 • 33 citations

Hyperthermia stimulates energy-proteasome-dependent protein degradation in cultured myotubes

2000 • 27 citations

Pathways of Protein Degradation in L6 Myotubes

1997 • 21 citations

Regulation of myosin and overall protein degradation in mouse C2 skeletal myotubes

1991 • 15 citations