The Mechanism of Muscle Contractio

The heat of shortening and the dynamic constants of muscle

1938 • 5,404 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

Muscle Structure and Theories of Contraction

1957 • 3,392 citations

The variation in isometric tension with sarcomere length in vertebrate muscle fibres

1966 • 3,052 citations

Proposed Mechanism of Force Generation in Striated Muscle

1971 • 2,256 citations

Changes in the Cross-Striations of Muscle during Contraction and Stretch and their Structural Interpretation

1954 • 1,655 citations

Structural Changes in Muscle During Contraction: Interference Microscopy of Living Muscle Fibres

1954 • 1,532 citations

Mechanism of adenosine triphosphate hydrolysis by actomyosin

1971 • 1,289 citations

Substructure of the myosin molecule

1971 • 1,062 citations

Actin And Myosin And Cell Movemen

1974 • 1,018 citations

Tension responses to sudden length change in stimulated frog muscle fibres near slack length

1977 • 853 citations

Energetic aspects of muscle contraction

1986 • 765 citations

Three-dimensional reconstruction of F-actin, thin filaments and decorated thin filaments

1970 • 552 citations

Handbook of Physiology. Section- 2

1967 • 520 citations

Adenylyl imidiodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage

1971 • 516 citations

The effects of ADP and phosphate on the contraction of muscle fibers

1985 • 507 citations

The relation between stiffness and filament overlap in stimulated frog muscle fibres.

1981 • 476 citations

Direct observation of motion of single F-actin filaments in the presence of myosin

1984 • 472 citations

Induced Changes in Orientation of the Cross-Bridges of Glycerinated Insect Flight Muscle

1965 • 471 citations

Periodic charge distributions in the myosin rod amino acid sequence match cross-bridge spacings in muscle

1982 • 464 citations

Muscle Contraction and Free Energy Transduction in Biological Systems

1985 • 446 citations

ADP dissociation from actomyosin subfragment 1 is sufficiently slow to limit the unloaded shortening velocity in vertebrate muscle.

1985 • 410 citations

Mechanism of Actomyosin Atpase and the Problem of Muscle Contractio

1979 • 407 citations

The Structural Basis of Muscular Contraction

1981 • 391 citations

Cross-bridge model of muscle contraction. Quantitative analysis

1980 • 373 citations

The characterization of myosin–product complexes and of product-release steps during the magnesium ion-dependent adenosine triphosphatase reaction

1974 • 364 citations

Studies on the structure of myosin

1962 • 363 citations

Structure of the actin–myosin interface

1981 • 349 citations

Shape and flexibility of the myosin molecule

1978 • 329 citations

Identification of myosin-binding sites on the actin sequence

1982 • 325 citations

Phosphate Release and Force Generation in Skeletal Muscle Fibers

1985 • 324 citations

F-actin is a helix with a random variable twist

1982 • 322 citations

A cross-bridge model of muscle contraction

1979 • 317 citations

Electron microscope studies of the organisation of the filaments in striated muscle

1953 • 304 citations

Differential localization of two myosins within nematode thick filaments

1983 • 303 citations

Evidence for cross-bridge attachment in relaxed muscle at low ionic strength.

1982 • 300 citations

X-ray evidence for radial cross-bridge movement and for the sliding filament model in actively contracting skeletal muscle

1973 • 293 citations

Energetics and mechanism of actomyosin adenosine triphosphatase

1976 • 287 citations

MYOSIN

1984 • 282 citations

Cooperative binding of myosin subfragment-1 to the actin-troponin-tropomyosin complex.

1980 • 273 citations

Orientation of spin-labeled myosin heads in glycerinated muscle fibers

1980 • 268 citations

Fast skeletal muscle myosin light chains 1 and 3 are produced from a single gene by a combined process of differential RNA transcription and splicing.

1984 • 265 citations

The magnesium ion-dependent adenosine triphosphatase of myosin. Two-step processes of adenosine triphosphate association and adenosine diphosphate dissociation

1974 • 261 citations

Relaxation of rabbit psoas muscle fibres from rigor by photochemical generation of adenosine‐5'‐triphosphate.

1984 • 256 citations

The reversibility of adenosine triphosphate cleavage by myosin

1973 • 249 citations

Crossbridge behaviour during muscle contraction

1985 • 249 citations

Mapping of actin-binding sites on the heavy chain of myosin subfragment 1

1983 • 248 citations

Orientation of spin labels attached to cross-bridges in contracting muscle fibres

1982 • 248 citations

Mechanism of the actomyosin adenosine triphosphatase. Evidence that adenosine 5'-triphosphate hydrolysis can occur without dissociation of the actomyosin complex

1979 • 243 citations

Ultrastructure of insect flight muscle

1968 • 233 citations

Segmental flexibility of the S-1 moiety of myosin

1973 • 233 citations

Mechanism of action of troponin . tropomyosin. Inhibition of actomyosin ATPase activity without inhibition of myosin binding to actin.

1981 • 231 citations

Protein structural domains in the Caenorhabditis elegans unc-54 myosin heavy chain gene are not separated by introns.

1983 • 230 citations

Time-resolved X-ray diffraction studies of the myosin layer-line reflections during muscle contraction

1982 • 230 citations

Fluorescence studies on heavy meromyosin-substrate interaction

1972 • 222 citations

A mutant affecting the heavy chain of myosin in Caenorhabditis elegans

1974 • 221 citations

The primary structure of actin from rabbit skeletal muscle. Completion and analysis of the amino acid sequence.

1975 • 216 citations

Regulation of skeletal muscle contraction

1972 • 212 citations

The limited tryptic cleavage of chymotryptic S-1 : An approach to the characterization of the actin site in myosin heads

1979 • 206 citations

Functional significance of flexibility in proteins

1983 • 190 citations

Intermediate states of subfragment 1 and actosubfragment 1 ATPase: reevaluation of the mechanism

1978 • 188 citations

Location of SH-1 and SH-2 in the heavy chain segment of heavy meromyosin

1978 • 186 citations

Changes in the X-ray reflections from contracting muscle during rapid mechanical transients and their structural implications

1983 • 182 citations

Exchange between inorganic phosphate and adenosine 5'-triphosphate in the medium by actomyosin subfragment 1

1980 • 177 citations

Dynamic study of F-actin by quasielastic scattering of laser light

1971 • 175 citations

Contraction of glycerinated muscle fibers as a function of the ATP concentration

1979 • 172 citations

Contraction kinetics of striated muscle fibres following quick changes in load

1966 • 169 citations

Electron microscopy of thin filaments decorated with a Ca2+-regulated myosin

1980 • 167 citations

Kinetics of acto-S1 interaction as a guide to a model for the crossbridge cycle

1984 • 167 citations

The use of synchrotron radiation in time-resolved X-ray diffraction studies of myosin layer-line reflections during muscle contraction

1980 • 157 citations

Variation of muscle stiffness with force at increasing speeds of shortening.

1975 • 156 citations

Homology of myosin DTNB light chain with alkali light chains, troponin C and parvalbumin

1976 • 155 citations

General model of myosin filament structure

1972 • 152 citations

Tension transients during steady shortening of frog muscle fibres.

1985 • 150 citations

Dissociation of the actin.subfragment 1 complex by adenyl-5'-yl imidodiphosphate, ADP, and PPi.

1980 • 150 citations

Relaxation of muscle fibres by photolysis of caged ATP

1982 • 149 citations

Initiation of active contraction by photogeneration of adenosine‐5'‐triphosphate in rabbit psoas muscle fibres.

1984 • 148 citations

The free heavy chain of vertebrate skeletal myosin subfragment 1 shows full enzymatic activity.

1982 • 145 citations

X-ray diffraction evidence for cross-bridge formation in relaxed muscle fibers at various ionic strengths

1984 • 145 citations

Crystallization of a non-muscle actin

1976 • 144 citations

The dependence of force and shortening velocity on substrate concentration in skinned muscle fibres from Rana temporaria.

1984 • 142 citations

Rotational dynamics of spin-labeled F-actin in the sub-millisecond time range

1979 • 141 citations

Active site trapping of nucleotides by crosslinking two sulfhydryls in myosin subfragment 1.

1979 • 139 citations

Light and X-ray diffraction studies of the filament lattice of glycerol-extracted rabbit psoas muscle

1967 • 139 citations

All myosin heads form bonds with actin in rigor rabbit skeletal muscle

1980 • 138 citations

Structure of insect fibrillar flight muscle in the presence and absence of ATP

1972 • 136 citations

The kinetics of magnesium adenosine triphosphate cleavage in skinned muscle fibres of the rabbit.

1984 • 136 citations

Polarized fluorescence from ε-ADP incorporated into F-actin in a myosin-free single fiber: Conformation of F-actin and hanges induced in it by heavy meromyosin

1978 • 135 citations

Fluorescence energy transfer between subfragment-1 and actin points in the rigor complex of actosubfragment-1

1979 • 133 citations

Electron microscopy of scallop myosin

1983 • 132 citations

Myosin-linked regulatory systems

1981 • 132 citations

Submillisecond rotational dynamics of spin-labeled myosin heads in myofibrils

1980 • 131 citations

Basic biology of muscles: A comparative approach

1983 • 129 citations

The ATPase mechanism of skeletal and smooth muscle acto-subfragment 1.

1984 • 128 citations

The sequence of the NH2-terminal 204-residue fragment of the heavy chain of rabbit skeletal muscle myosin.

1983 • 128 citations

Millisecond time-resolved changes in x-ray reflections from contracting muscle during rapid mechanical transients, recorded using synchrotron radiation.

1981 • 128 citations

Three-dimensional reconstruction of thin filaments decorated with a Ca2+-regulated myosin

1982 • 127 citations

A Mechanochemical Mechanism for Muscle Contraction

1971 • 125 citations

Muscle Filament Structure and Muscle Contraction

1975 • 124 citations

Motion of subfragment-1 in myosin and its supramolecular complexes: saturation transfer electron paramagnetic resonance.

1975 • 122 citations

ATP-dependent movement of myosin in vitro: characterization of a quantitative assay.

1984 • 121 citations

The effect of the performance of work on total energy output and metabolism during muscular contraction

1974 • 121 citations

Photoaffinity labelling with an ATP analog of the N-terminal peptide of myosin

1979 • 117 citations

Polarization of fluorescence from single skinned glycerinated rabbit psoas fibers in rigor and relaxation

1977 • 116 citations

Polarization of Tryptophan Fluorescence from Single Striated Muscle Fibers

1972 • 115 citations

The Transference of the Muscle Energy in the Contraction Cycle

1954 • 113 citations

Cross-bridge orientation in skeletal muscle measured by linear dichroism of an extrinsic chromophore

1982 • 112 citations

Polarization from a Helix of Fluorophores and its Relation to that Obtained from Muscle

1975 • 110 citations

ATP binding to a protease-resistant core of actin.

1976 • 110 citations

Angles of nucleotides bound to cross-bridges in glycerinated muscle fiber at various concentrations of ϵ-ATP, ϵ-ADP and ϵ-AMPPNP detected by polarized fluorescence

1981 • 110 citations

Changes in muscle crossbridges when β,γ-imido-ATP binds to myosin

1976 • 109 citations

Crosslinked myosin subfragment 1: a stable analogue of the subfragment-1.ATP complex.

1983 • 108 citations

Physiological effects accompanying the removal of myosin LC2 from skinned skeletal muscle fibers.

1982 • 107 citations

Monomeric Acanthamoeba myosins I support movement in vitro.

1985 • 106 citations

Studies on conformation of F-actin in muscle fibers in the relaxed state, rigor, and during contraction using fluorescent phalloidin.

1983 • 104 citations

Frog skeletal muscle thick filaments are three-stranded.

1983 • 104 citations

Arrangement of the heads of myosin in relaxed thick filaments from tarantula muscle

1985 • 103 citations

Some self-consistent two-state sliding filament models of muscle contraction

1975 • 103 citations

Phosphorus-31 nuclear magnetic resonance evidence for two conformations of myosin subfragment-1.cntdot.nucleotide complexes

1981 • 103 citations

Muscle proteins, muscle contraction and cation transport

1973 • 103 citations

Contractile Mechanisms in Muscle

1984 • 102 citations

Transient phase of adenosine triphosphate hydrolysis by myosin, heavy meromyosin, and subfragment 1

1977 • 102 citations

Three-dimensional structure of the complex of skeletal muscle actin and bovine pancreatic DNAse I at 6-A resolution.

1981 • 100 citations

Hinge region of myosin

1973 • 100 citations

Effect of nucleotide binding on the proximity of the essential sulfhydryl groups of myosin. Chemical probing of movement of residues during conformational transitions

1977 • 99 citations

Identification of an active site peptide of skeletal myosin after photoaffinity labeling with N-(4-azido-2-nitrophenyl)-2-aminoethyl diphosphate.

1985 • 99 citations

Proton Nuclear‐Magnetic‐Resonance Spectroscopy of Myosin Subfragment 1 Isoenzymes

1981 • 98 citations

Transient kinetics of ADP and AMP-PNP binding to subfragment 1 and actosubfragment 1

1982 • 98 citations

Can a myosin molecule bind to two actin filaments?

1978 • 96 citations

Internal motions in myosin

1979 • 96 citations

Three-dimensional reconstruction of rigor insect flight muscle from tilted thin sections

1984 • 94 citations

Effect of nucleotides and pyrophosphate on spin labels bound to S1 thiol groups of myosin

1970 • 92 citations

Fluctuations in polarized fluorescence: evidence that muscle cross bridges rotate repetitively during contraction.

1979 • 91 citations

Structural Implications of the Myosin Amino Acid Sequence

1984 • 91 citations

The cross-bridge theory

1983 • 90 citations

A note suggesting that the cross-bridge attachment during muscle contraction may take place in two stages

1973 • 90 citations

Spatial proximity of the two essential sulfhydryl groups of myosin

1974 • 89 citations

Fluorescence energy transfer in myosin subfragment-1

1980 • 88 citations

Proteolysis and structure of skeletal muscle actin.

1984 • 88 citations

Structural evidence that myosin heads may interact with two sites on F-actin

1982 • 88 citations

Electron microscopy and image analysis of myosin filaments from scallop striated muscle

1983 • 87 citations

The significance of the slow dissociation of divalent metal ions from myosin ‘regulatory’ light chains

1977 • 85 citations

An actin-binding site on the 20K fragment of myosin subfragment 1

1982 • 83 citations

Interaction of Myosin Subfragment-1 with Actin

1979 • 83 citations

Thick myofilament mass determination by electron scattering measurements with the scanning transmission electron microscope

1981 • 83 citations

Reaction of 5,5'-dithiobis(2-nitrobenzoic acid) with myosin subfragment one: evidence for formation of a single protein disulfide with trapping of metal nucleotide at the active site

1980 • 83 citations

Actin-myosin interactions visualized by the quick-freeze, deep-etch replica technique

1983 • 83 citations

On the mechanism of energy transduction in myosin subfragment 1.

1984 • 82 citations

Cross-bridge conformation as revealed by x-ray diffraction studies on insect flight muscles with ATP analogues

1975 • 82 citations

Reciprocal reactivities of specific thiols when actin binds to myosin.

1976 • 82 citations

Structure of the actin-myosin complex in the presence of ATP.

1985 • 81 citations

Two rigor states in skinned crayfish single muscle fibers.

1976 • 81 citations

Diversity of cross-bridge configurations in invertebrate muscles

1975 • 81 citations

Evidence for a Refractory State of Heavy Meromyosin and Subfragment-1 Unable to Bind to Actin in the Presence of ATP

1973 • 80 citations

Interpretation of the low angle X-ray diffraction from insect flight muscle in rigor

1980 • 80 citations

Fraction of myosin heads bound to thin filaments in rigor fibrils from insect flight and vertebrate muscles

1981 • 78 citations

Topography of the Myosin Molecule as Visualized by an Improved Negative Staining Method

1978 • 78 citations

Microsecond rotational motions of eosin-labeled myosin measured by time-resolved anisotropy of absorption and phosphorescence

1984 • 76 citations

The Binding Constant of ATP to Myosin S1 Fragment

1977 • 76 citations

Variation of muscle stiffness with tension during tension transients and constant velocity shortening in the frog.

1981 • 76 citations

Structure of the myosin projections on native thick filaments from vertebrate skeletal muscle

1984 • 75 citations

The amino acid sequence of actin from chicken skeletal muscle actin and chicken gizzard smooth muscle actin

1979 • 74 citations

Kinetic and Thermodynamic Properties of the Ternary Complex between F‐actin, Myosin Subfragment 1 and Adenosine 5′‐[β,γ‐imido]triphosphate

1982 • 74 citations

Vanadare and phosphate ions reduce tension and increase cross-bridge kinetics in chemically skinned heart muscle

1981 • 74 citations

Electron microscopic visualization of the SH1 thiol of myosin by the use of an avidin-biotin system

1984 • 74 citations

Light-chain movement and regulation in scallop myosin

1983 • 73 citations

Packing analysis of crystalline myosin subfragment-1

1985 • 73 citations

Time-Resolved X-Ray Diffraction Studies on Vertebrate Striated Muscle

1983 • 73 citations

Mechanism of the actomyosin ATPase: effect of actin on the ATP hydrolysis step.

1981 • 72 citations

X-ray diffraction of actively shortening muscle.

1976 • 71 citations

Proteolysis and the domain organization of myosin subfragment 1.

1984 • 70 citations

An electron microscopic and optical diffraction analysis of the structure of Limulus telson muscle thick filaments.

1982 • 70 citations

Torsional motion of eosin-labeled F-actin as detected in the time-resolved anisotropy decay of the probe in the sub-millisecond time range

1984 • 69 citations

The position of tropomyosin in muscle thin filaments

1980 • 69 citations

Muscle Crossbridges: Absence of Direct Effect of Calcium on Movement Away from the Thick Filaments

1976 • 68 citations

Cross-bridges and the mechanism of muscle contraction

1983 • 68 citations

Foerster energy transfer measurements of thiol 1 to thiol 2 distances in myosin subfragment 1

1983 • 67 citations

Muscle and Nonmuscle Motility

1983 • 67 citations

Three-Dimensional Image Analysis of the Complex of Thin Filaments and Myosin Molecules from Skeletal Muscle. II. The Multi-Domain Structure of Actin-Myosin SI Complex1

1981 • 66 citations

Nucleation of polar actin filament assembly by a positively charged surface.

1979 • 66 citations

Distribution of mass in relaxed frog skeletal muscle and its redistribution upon activation

1985 • 65 citations

Flexibility of myosin rod, light meromyosin, and myosin subfragment-2 in solution.

1977 • 65 citations

Interactions of the actin and nucleotide binding sites on myosin subfragment 1.

1976 • 64 citations

Rate-limiting step in the actomyosin adenosine triphosphatase cycle

1984 • 63 citations

A new myosin fragment: visualization of the regulatory domain

1984 • 63 citations

Co-ordinated electron microscopy and X-ray studies of glycerinated insect flight muscle. I. X-ray diffraction monitoring during preparation for electron microscopy of muscle fibres fixed in rigor, in ATP and in AMPPNP

1983 • 61 citations

Formation and characterization of myosin hybrids containing essential light chains and heavy chains from different muscle myosins.

1981 • 61 citations

Evidence for cross-bridge order in contraction of glycerinated skeletal muscle.

1983 • 61 citations

Muscle Contraction

1982 • 61 citations

The mechanism of the skeletal muscle myosin ATPase. I. Identity of the myosin active sites.

1979 • 60 citations

Rapid helix--coil transitions in the S-2 region of myosin.

1979 • 60 citations

The quantitative measurement of rotational motion of the subfragment‐1 region of myosin by saturation transfer EPR spectroscopy

1975 • 58 citations

A model of myosin crossbridge structure consistent with the low-angle X-ray diffraction pattern of vertebrate muscle

1980 • 57 citations

Cross-linking of myosin subfragment 1. Nucleotide-enhanced modification by a variety of bifunctional reagents.

1980 • 57 citations

X-Ray Diffraction Studies of the Heart

1980 • 56 citations

Actin microcrystals and tubes formed in the presence of gadolinium ions

1978 • 56 citations

Recent X-ray diffraction studies of muscle

1968 • 56 citations

X-ray diffraction evidence that actin is a 100 Å filament

1984 • 56 citations

Effects of tryptic digestion on myosin subfragment- 1 and its actin-activated ATPase

1982 • 55 citations

Angle of active site of myosin heads in contracting muscle during sudden length changes

1985 • 55 citations

Site-specific inhibition of myosin-mediated motility in vitro by monoclonal antibodies.

1985 • 55 citations

Isolation and distribution of myosin isoenzymes in chicken pectoralis muscle

1981 • 55 citations

Head Rotation or Dissociation?

1978 • 54 citations

Structure of the actin molecule determined from electron micrographs of crystalline actin sheets with a tentative alignment of the molecule in the actin filament

1983 • 54 citations

Oxygen exchange between phosphate and water accompanies calcium-regulated ATPase activity of skinned fibers from rabbit skeletal muscle.

1985 • 53 citations

Conformational transitions in the subfragment-2 region of myosin

1980 • 53 citations

Stress does not alter the conformation of a domain of the myosin cross-bridge in rigor muscle fibres

1981 • 53 citations

Co-ordinated electron microscopy and X-ray studies of glycerinated insect flight muscle. II. Electron microscopy and image reconstruction of muscle fibres fixed in rigor, in ATP and in AMPPNP

1983 • 52 citations

Intermediate states of actomyosin adenosine triphosphatase

1976 • 52 citations

Structure of myosin subfragment 1 from low-angle x-ray scattering

1980 • 52 citations

Helical disorder and the filament structure of F-actin are elucidated by the angle-layered aggregate

1983 • 51 citations

Rate-limiting step in the actomyosin adenosine triphosphatase cycle: experiments with myosin subfragment 1 crosslinked to actin

1985 • 51 citations

Direct visualization of the myosin crossbridge helices on relaxed rabbit psoas thick filaments

1983 • 51 citations

The Crossbridge Theory

1979 • 50 citations

Isolation and partial renaturation of proteolytic fragments of the myosin head.

1984 • 50 citations

Time‐dependent fluorescence depolarization and lifetime studies of myosin subfragment‐one in the presence of nucleotide and actin

1975 • 50 citations

Energetics and kinetics of the interconversion of two myosin subfragment-1.cntdot.adenosine 5'-diphosphate complexes as viewed by phosphorus-31 nuclear magnetic resonance

1981 • 49 citations

Macromolecular Assembly of Actin

1983 • 49 citations

Muscle Proteins, Muscle Contraction and Cation Transport.

1974 • 49 citations

Comparison of the calcium sensitivity of actomyosin from native and L₂-deficient myosin

1977 • 48 citations

A comparison of order and orientation of crossbridges in rigor and relaxed muscle fibres using fluorescence polarization

1983 • 47 citations

Some Physical Studies of the Contractile Mechanism in Muscle

1982 • 47 citations

Generation of force by single-headed myosin

1978 • 47 citations

Energetics of the equilibrium between two nucleotide-free myosin subfragment 1 states using fluorine-19 NMR

1982 • 47 citations

Fluorescence energy transfer between probes on actin and probes on myosin

1984 • 46 citations

An actomyosin motor

1982 • 46 citations

Flexibility of light meromyosin and other coiled-coil α-helical proteins

1983 • 46 citations

Effect of trinitrophenylation on myosin ATPase

1968 • 45 citations

The isolated heavy chain of an Acanthamoeba myosin contains full enzymatic activity.

1978 • 45 citations

Structure of Muscle Filaments Studied by Electron Microscopy

1985 • 45 citations

Formation of a ternary complex: Actin, 5′-adenylyl imidodiphosphate, and the subfragments of myosin

1978 • 45 citations

Bending motions and internal motions in the myosin rod

1982 • 44 citations

Crystallization of myosin subfragment 1.

1984 • 44 citations

X-ray evidence for two structural states of the actomyosin cross-bridge in muscle fibers.

1984 • 43 citations

Small-angle X-ray scattering from myosin heads in relaxed and rigor frog skeletal muscles

1983 • 43 citations

Fluorescence energy transfer between the myosin subfragment-1 isoenzymes and F-actin in the absence and presence of nucleotides

1983 • 42 citations

Force — Sarcomere-Length Relation and Filament Length in Rat Extensor Digitorum Muscle

1984 • 42 citations

Calcium-sensitive binding of heavy meromyosin to regulated actin requires light chain 2 and the head-tail junction

1983 • 42 citations

The amino acid sequence and stability predictions of the hinge region in myosin subfragment 2.

1985 • 41 citations

Muscle Cross-Bridges: Do They Rotate?

1984 • 41 citations

Cross-linking of actin filaments by heavy meromyosin

1979 • 40 citations

Equatorial X-ray intensities and isometric force levels in frog sartorius muscle

1979 • 39 citations

Intensification of the 5.9-nm actin layer line in contracting muscle

1984 • 38 citations

Effect of actin concentration on the intermediate oxygen exchange of myosin; relation to the refractory state and the mechanism of exchange

1978 • 37 citations

Tryptic digestion as a probe of myosin S-1 conformation.

1982 • 37 citations

Stoichiometry of actin X S-1 cross-linked complex.

1984 • 37 citations

Tension generation by threads of contractile proteins.

1977 • 37 citations

Stiffness of glycerinated rabbit psoas fibers in the rigor state. Filament-overlap relation

1984 • 35 citations

Fluctuations in tension during contraction of single muscle fibers

1977 • 35 citations

Saturation transfer electron paramagnetic resonance of spin-labeled muscle fibers

1984 • 35 citations

Evidence for the two-step binding of ATP to myosin subfragment 1 by the rapid-flow-quench method

1983 • 35 citations

Crossbridge angle when ADP is bound to myosin

1974 • 35 citations

Conformational stability of the myosin rod

1984 • 33 citations

The inhibition of muscle contraction by adenosine 5' (beta, gamma-imido) triphosphate and by pyrophosphate

1985 • 33 citations

Inhibition of acanthamoeba actomyosin-II ATPase activity and mechanochemical function by specific monoclonal antibodies.

1984 • 32 citations

Stoichiometry of covalent actin-subfragment 1 complexes formed on reaction with a zero-length crosslinking compound

1984 • 32 citations

Nucleotide-induced changes in the proteolytically sensitive regions of myosin subfragment 1

1984 • 32 citations

ADP binds similarly to rigor muscle myofibrils and to actomyosin‐subfragment one

1984 • 32 citations

Muscle Crossbridge Stroke and Activity Revealed by Optical Diffraction

1978 • 32 citations

Contraction of the A band

1963 • 31 citations

Fluorescence energy transfers in labelled G-actin and F-actin

1984 • 31 citations

Length of myosin rod and its proteolytic fragments determined by electron microscopy

1984 • 30 citations

Actomyosin ATPase and Muscle Contraction

1981 • 30 citations

X-Ray Diffraction Studies of Muscle

1981 • 30 citations

Assembly and kinetic properties of myosin light chain isozymes from fast skeletal muscle

1983 • 30 citations

Spatial relationship between a fast-reacting thiol and a reactive lysine residue of myosin subfragment 1

1982 • 29 citations

Fluorescence energy transfer studies on the proximity of the two essential thiols of myosin subfragment-1.

1983 • 29 citations

Role of magnesium binding to myosin in controlling the state of cross-bridges in skeletal rabbit muscle

1983 • 28 citations

Spectral shift in heavy-meromyosin induced by substrate

1966 • 28 citations

Fluorescence of fluorescein attached to myosin SH1 distinguishes the rigor state from the actin-myosin-nucleotide state

1984 • 28 citations

Mobility and function in proteins and nucleic acids

1984 • 28 citations

Three-dimensional image analysis of the complex of thin filaments and myosin molecules from skeletal muscle. II. The multi-domain structure of actin-myosin S1 complex.:II. The Multi-Domain Structure of Actin-Myosin S 1 Complex

1981 • 28 citations

X-ray diffraction of strained muscle fibers in rigor.

1981 • 27 citations

Regulatory and essential light-chain interactions in scallop myosin

1982 • 27 citations

Spin-label study of actin-myosin-nucleotide interactions in contracting glycerinated muscle fibers

1981 • 27 citations

Interaction of actin with spin-labeled heavy meromyosin in the presence of nucleotides

1973 • 26 citations

Resonance energy transfer evidence for two attached states of the actomyosin complex

1985 • 26 citations

Non‐cooperative response of actin‐cystein 373 in cooperatively behaving regulated actin filaments

1979 • 26 citations

Orientation and rotational mobility of spin-labelled myosin heads in insect flight muscle in rigor

1983 • 26 citations

Analysis of the metal-induced conformational change in myosin with a monoclonal antibody to light chain two

1985 • 25 citations

Distance measurement between the active site and Cys 177 of the alkali one light chain of subfragment 1 from rabbit skeletal muscle

1983 • 25 citations

Bound trace element content of bovine retinal disk membranes as determined by particle-induced x-ray emission

1985 • 25 citations

Tension development in skinned glycerinated rabbit psoas fiber segments irrigated with soluble myosin fragments

1976 • 24 citations

Activation by ADP and the correlation between tension and ATPase activity in insect fibrillar muscle

1970 • 24 citations

Does myosin‐substrate interaction in vitro result in a delocalized conformation change?

1975 • 24 citations

Molecular Basis of Contraction in Cross-Striated Muscles and Relevance to Motile Mechanisms in Other Cells

1983 • 24 citations

The interaction of actin monomers with myosin heads and other muscle proteins

1976 • 23 citations

The mechanochemistry of force production in muscle

1981 • 23 citations

Angles of Fluorescently Labelled Myosin Heads and Actin Monomers in Contracting and Rigor Stained Muscle Fiber

1984 • 23 citations

Tryptic digestion of rabbit skeletal myofibrils: an enzymatic probe of myosin cross-bridges

1984 • 22 citations

Cross-bridge behavior in rigor muscle

1980 • 21 citations

Predominant attached state of myosin cross-bridges during contraction and relaxation at low ionic strength

1984 • 21 citations

Electron microscopy of cross-linked scallop myosin

1985 • 21 citations

Three-dimensional disorder of dipolar probes in a helical array. Application to muscle cross-bridges

1982 • 21 citations

Cross-bridge movements during a slow length change of active muscle

1984 • 20 citations

Structural fluctuations in the steady state of muscular contraction

1975 • 20 citations

Kinetics of tryptophan fluorescence enhancement in myofibrils during ATP hydrolysis.

1985 • 20 citations

G‐actin binding quenches internal motions in myosin subfragment‐1

1980 • 20 citations

Structural aspects of actomyosin interaction

1981 • 20 citations

Location of the SH group of the alkali light chain on the myosin head as revealed by electron microscopy

1985 • 20 citations

Binding of heavy meromyosin and subfragment-1 to thin filaments in myofibrils and single muscle fibers

1980 • 20 citations

Myosin heavy chain-light chain recombinations and interactions between the two classes of light chains.

1983 • 20 citations

Modification of crossbridge states by ethylene glycol in insect flight muscle

1984 • 20 citations

Single turnovers of adenosine 5'-triphosphate by myofibrils and actomyosin subfragment 1

1981 • 20 citations

Three-Dimensional Image Analysis of the Complex of Thin Filaments and Myosin Molecules from Skeletal Muscle. III. The Multi-Domain Structure of Actin-Heavy Meromyosin Complex1

1981 • 19 citations

Studies on the role of myosin light chain-LC2 in tension generation

1980 • 19 citations

Length-Tension-Velocity Relationships Studied in Short Consecutive Segments of Intact Muscle Fibres of the Frog

1984 • 19 citations

Internal motions in myosin. 2

1981 • 19 citations

Abstracts of the Eighth European Conference on Muscle and Motility including the Erwin Riesch Symposium on Muscle Proteins ? Polymorphism and Isoforms Heidelberg, 17?20 September 1979

1980 • 18 citations

Investigation of the shape and size of myosin subfragment 1 using small-angle x-ray scattering

1978 • 18 citations

X-ray structure analysis of thin filaments of a molluscan smooth muscle in the living relaxed state

1983 • 17 citations

Observation of Steady Streamings in a Solution of Mg-ATP and Acto-Heavy Meromyosin from Rabbit Skeletal Muscle1

1978 • 17 citations

Energy transduction in myosin

1984 • 17 citations

Light chain dependent effects of actin binding on the swivel in myosin

1985 • 16 citations

The incorporation of radioactive phosphate into ATP in glycerinated fibres stretched or released during contraction.

1974 • 15 citations

Comparison of the equilibrium binding of heavy meromyosin and myosin to f‐actin in the presence and absence of the troponin‐tropomyosin complex

1982 • 14 citations

Tension transients in fibrillar muscle fibres as affected by stretch-dependent binding of AMP-PNP: A teinochemical effect?

1978 • 13 citations

The role of magnesium adenosine triphosphate in the contractile kinetics of insect fibrillar flight muscle

1983 • 12 citations

X-ray scattering by single-headed heavy meromyosin

1984 • 12 citations

Crossbridge order and orientation in resting single glycerinated muscle fibres studied by linear dichroism of bound rhodamine labels

1984 • 12 citations

Reversible helix‐coil transition of pig stomach myosin rod

1983 • 11 citations

The dynamics of myosin and actin in solution are compatible with the mechanical features of the cross-bridge hypothesis

1981 • 11 citations

Is the SII portion of the cross-bridge in glycerinated rabbit psoas fibers compliant in the rigor state?

1984 • 10 citations

Myosin Flexibility

1982 • 10 citations

Actin-Induced Local Conformational Change in the Myosin Molecule: II. Conformational Change around the S2 Thiol Group Related to the Essential Intermediate of ATP Hydrolysis

1980 • 9 citations

X-ray equatorial analysis of crab striated muscle in the relaxed and rigor states

1981 • 9 citations

Magnesium adenosine 5'-diphosphate influences proteolytic susceptibility of myosin in myofibrils

1982 • 9 citations

Evidence for actomyosin conformational changes involved in tension generation.

1983 • 8 citations

The Nature of the Actin Cross-Bridge Interaction

1984 • 7 citations

Limitations in the use of actomyosin threads as model contractile systems

1980 • 7 citations

Myosin Phosphorylation

1981 • 7 citations

The dependence of rigor tension on sarcomere length in vertebrate muscle

1974 • 7 citations

Kinetic rates of tryptic digestion of bovine cardiac myofibrils. An improved measurement of cross-bridge dissociation.

1985 • 6 citations

Effects of ATP and ADP on Hydrogen-Deuterium Exchange in Heavy Meromyosin

1977 • 6 citations

Structure of Limulus and Other Invertebrate Thick Filaments

1984 • 3 citations

Cinematographic Studies on the A-Band Length Changes During Ca-Activated Contraction in Horseshoe Crab Muscle Myofibrils

1984 • 3 citations