Cloning, recombinant expression, and characterization of basic fibroblast growth factor

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

Angiogenic Factors

1987 • 3,702 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

Structural Characterization and Biological Functions of Fibroblast Growth Factor

1987 • 1,299 citations

Recent developments in the cell biology of basic fibroblast growth factor.

1989 • 1,049 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Human KGF is FGF-Related with Properties of a Paracrine Effector of Epithelial Cell Growth

1989 • 989 citations

Expression of active human factor VIII from recombinant DNA clones

1984 • 699 citations

Human basic fibroblast growth factor: nucleotide sequence and genomic organization.

1986 • 604 citations

The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors.

1988 • 425 citations

‘ATG vectors’ for regulated high-level expression of cloned genes in Escherichia coli

1985 • 392 citations

Basic fibroblast growth factor fused to a signal peptide transforms cells

1988 • 379 citations

Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies

1985 • 335 citations

Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family.

1989 • 294 citations

Effect of fibroblast growth factor and lipoproteins on the proliferation of endothelial cells derived from bovine adrenal cortex, brain cortex, and corpus luteum capillaries

1986 • 273 citations

Purification from a human hepatoma cell line of a basic fibroblast growth factor-like molecule that stimulates capillary endothelial cell plasminogen activator production, DNA synthesis, and migration.

1986 • 272 citations

Recombinant basic fibroblast growth factor accelerates wound healing

1988 • 269 citations

Purification and characterization of heparin-binding endothelial cell growth factors.

1986 • 263 citations

bFGF is the putative natural growth factor for human melanocytes

1987 • 259 citations

Accelerated wound repair, cell proliferation, and collagen accumulation are produced by a cartilage-derived growth factor.

1985 • 221 citations

Primary structure of bovine brain acidic fibroblast growth factor (FGF)

1985 • 213 citations

Acidic fibroblast growth factor (FGF) from bovine brain: amino-terminal sequence and comparison with basic FGF.

1985 • 178 citations

Growth of normal human keratinocytes and fibroblasts in serum‐free medium is stimulated by acidic and basic fibroblast growth factor

1989 • 174 citations

Stimulation of Growth of Keratinocytes by Basic Fibroblast Growth Factor

1988 • 172 citations

Processing, secretion, and biological properties of a novel growth factor of the fibroblast growth factor family with oncogenic potential.

1988 • 171 citations

Complete primary structure of prostatropin, a prostate epithelial cell growth factor

1986 • 163 citations

Cloning and expression of cDNA encoding human basic fibroblast growth factor

1987 • 158 citations

Stabilizing basic fibroblast growth factor using protein engineering

1988 • 153 citations

Transformation of mouse BALB/c 3T3 cells with human basic fibroblast growth factor cDNA.

1988 • 150 citations

Mutants of Escherichia coli with an Altered Tryptophanyl-Transfer Ribonucleic Acid Synthetase

1968 • 147 citations

Expression of human basic fibroblast growth factor cDNA in baby hamster kidney-derived cells results in autonomous cell growth.

1988 • 134 citations

A form of human basic fibroblast growth factor with an extended amino terminus

1987 • 110 citations

Production, biological activity, and structure of recombinant basic fibroblast growth factor and an analog with cysteine replaced by serine.

1988 • 100 citations

Addition of growth hormone secretion signal to basic fibroblast growth factor results in cell transformation and secretion of aberrant forms of the protein.

1988 • 98 citations

Peptide mapping by polyacrylamide gel electrophoresis after cleavage at aspartyl-prolyl peptide bonds in sodium dodecyl sulfate-containing buffers

1984 • 88 citations

Expression and processing of biologically active fibroblast growth factors in the yeast Saccharomyces cerevisiae.

1988 • 81 citations

Expression of cDNA encoding human basic fibroblast growth factor in E.coli

1987 • 81 citations

Clinical applications of heparin‐binding growth factors

1988 • 76 citations

Production and characterization of human basic fibroblast growth factor from Escherichia coli.

1988 • 76 citations

Isolation of an amino terminal extended form of basic fibroblast growth factor

1986 • 74 citations

Amino-terminal sequence of a large form of basic fibroblast growth factor isolated from human benign prostatic hyperplastic tissue

1987 • 69 citations

Clinical And Experimental Approaches To Dermal And Epidermal Repair: NORMAL AND CHRONIC WOUNDS

1991 • 65 citations

Nucleotide sequence of the promoter-operator region of the tryptophan operon of Escherichia coli

1978 • 64 citations