Expression and processing of biologically active fibroblast growth factors in the yeast Saccharomyces cerevisiae.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Angiogenic Factors

1987 • 3,702 citations

Transformation of yeast.

1978 • 2,267 citations

Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix.

1987 • 1,045 citations

Heparin Affinity: Purification of a Tumor-Derived Capillary Endothelial Cell Growth Factor

1984 • 937 citations

Heparin protects basic and acidic FGF from inactivation

1986 • 856 citations

Tumor Growth and Neovascularization: An Experimental Model Using the Rabbit Cornea 2

1974 • 762 citations

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

1987 • 718 citations

Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF.

1985 • 710 citations

Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-α-factor

1984 • 698 citations

Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization

1986 • 679 citations

Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor.

1984 • 624 citations

Human basic fibroblast growth factor: nucleotide sequence and genomic organization.

1986 • 604 citations

An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family

1987 • 525 citations

Alpha-factor-directed synthesis and secretion of mature foreign proteins in Saccharomyces cerevisiae.

1984 • 477 citations

Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells invitro: Implications for a role of heparinase-like enzymes in the neovascular response

1987 • 416 citations

Basic fibroblast growth factor fused to a signal peptide transforms cells

1988 • 379 citations

Fibroblast growth factor

1986 • 367 citations

Molecular Characterization of Fibroblast Growth Factor: Distribution and Biological Activities in Various Tissues

1986 • 340 citations

Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies

1985 • 335 citations

Purification of two distinct growth factors from bovine neural tissue by heparin affinity chromatography

1984 • 298 citations

Pure brain-derived acidic fibroblast growth factor is a potent angiogenic vascular endothelial cell mitogen with sequence homology to interleukin 1.

1985 • 294 citations

cDNA sequence of human transforming gene hst and identification of the coding sequence required for transforming activity.

1987 • 293 citations

Secondary ion mass spectrometry with cesium ion primary beam and liquid target matrix for analysis of bioorganic compounds

1982 • 284 citations

Effect of fibroblast growth factor and lipoproteins on the proliferation of endothelial cells derived from bovine adrenal cortex, brain cortex, and corpus luteum capillaries

1986 • 273 citations

Retina- and eye-derived endothelial cell growth factors: partial molecular characterization and identity with acidic and basic fibroblast growth factors

1985 • 268 citations

Purification and characterization of heparin-binding endothelial cell growth factors.

1986 • 263 citations

Human tumor cells synthesize an endothelial cell growth factor that is structurally related to basic fibroblast growth factor.

1986 • 247 citations

Purification of two astroglial growth factors from bovine brain

1985 • 235 citations

Endothelial cell mitogens derived from retina and hypothalamus: biochemical and biological similarities.

1984 • 224 citations

Complete primary structure of prostatropin, a prostate epithelial cell growth factor

1986 • 163 citations

Transformation of mouse BALB/c 3T3 cells with human basic fibroblast growth factor cDNA.

1988 • 150 citations

Human Cu/Zn superoxide dismutase cDNA: isolation of clones synthesising high levels of active or inactive enzyme from an expression library

1985 • 149 citations

Methods for preparation of media, supplements, and substrata for serum-free animal cell culture

1984 • 146 citations

A unique family of endothelial cell polypeptide mitogens: the antigenic and receptor cross-reactivity of bovine endothelial cell growth factor, brain-derived acidic fibroblast growth factor, and eye-derived growth factor-II.

1985 • 146 citations

Developing brain produces an angiogenesis factor.

1986 • 143 citations

[9] Isolation and characterization of acidic and basic fibroblast growth factor

1987 • 139 citations

Role of mRNA translational efficiency in bovine growth hormone expression in Escherichia coli.

1984 • 131 citations

Isolation of a rearranged human transforming gene following transfection of Kaposi sarcoma DNA.

1987 • 125 citations

Structural evidence that endothelial cell growth factor beta is the precursor of both endothelial cell growth factor alpha and acidic fibroblast growth factor.

1986 • 121 citations

Multiple forms of basic fibroblast growth factor: amino-terminal cleavages by tumor cell- and brain cell-derived acid proteinases.

1987 • 117 citations

Chemical synthesis of a gene for human epidermal growth factor urogastrone and its expression in yeast.

1983 • 115 citations

Characterization of recombinant human epidermal growth factor produced in yeast

1988 • 78 citations

Biosynthetic human EGF accelerates healing of Neodecadron-treated primate corneas.

1985 • 75 citations

High level expression of proinsulin in the yeast, Saccharomyces cerevisiae

1987 • 74 citations

Isolation of an amino terminal extended form of basic fibroblast growth factor

1986 • 74 citations

Recombinant polypeptide from the endonuclease region of the acquired immune deficiency syndrome retrovirus polymerase (pol) gene detects serum antibodies in most infected individuals

1986 • 71 citations

Amino-terminal sequence of a large form of basic fibroblast growth factor isolated from human benign prostatic hyperplastic tissue

1987 • 69 citations

Bovine brain-derived growth factor. Purification and characterization of its interaction with responsive cells.

1986 • 69 citations

Expression in yeast of a Plasmodium vivax antigen of potential use in a human malaria vaccine.

1987 • 66 citations

Antigenicity and immunogenicity of domains of the human immunodeficiency virus (HIV) envelope polypeptide expressed in the yeast Saccharomyces cerevisiae

1987 • 61 citations

Purification in high yield of brain fibroblast growth factor by preparative isoelectric focusing at pH 9.6.

1982 • 60 citations

Stimulation of wound healing, using brain extract with fibroblast growth factor (PGF) activity

1982 • 60 citations

Deleted Work

1955 • 0 citations