Primary Pulmonary Responses to Toxic Agents

Aviat space environ med

1992 • 5,078 citations

LYSOSOME FUNCTION IN THE REGULATION OF THE SECRETORY PROCESS IN CELLS OF THE ANTERIOR PITUITARY GLAND

1966 • 951 citations

Lipid peroxidation damage to cell components.

1973 • 925 citations

Carbon Tetrachloride Hepatotoxicity: An Example of Lethal Cleavage

1973 • 729 citations

New antibiotics, bleomycin A and B.

1966 • 721 citations

The type 2 cell as progenitor of alveolar epithelial regeneration. A cytodynamic study in mice after exposure to oxygen.

1974 • 698 citations

Angiotensin-Converting Enzyme: Vascular Endothelial Localization

1976 • 644 citations

Pulmonary oxygen toxicity: a review.

1971 • 619 citations

Aryl Hydrocarbon Hydroxylase Inducibility and Bronchogenic Carcinoma

1973 • 601 citations

Transformation of alveolar Type 2 cells to Type 1 cells following exposure to NO2

1975 • 577 citations

Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity

1974 • 540 citations

Chemicals, Drugs, and Lipid Peroxidation

1976 • 520 citations

Toxicity of Pyrrolizidine Alkaloids

1968 • 474 citations

Morphological basis of alveolar-capillary gas exchange.

1973 • 473 citations

The pathogenesis of bleomycin-induced pulmonary fibrosis in mice.

1974 • 469 citations

Superoxide dismutase and pulmonary oxygen toxicity

1974 • 462 citations

Renewal of alveolar epithelium in the rat following exposure to NO2.

1973 • 429 citations

Pathogenesis and reversibility of the pulmonary lesions of oxygen toxicity in monkeys. II. Ultrastructural and morphometric studies.

1969 • 420 citations

Hyaline membrane disease

1956 • 413 citations

Lung surfactant

1974 • 407 citations

DEVELOPMENT OF FINE STRUCTURAL DAMAGE TO ALVEOLAR AND CAPILLARY LINING CELLS IN OXYGEN-POISONED RAT LUNGS

1967 • 393 citations

The toxic actions of pyrrolizidine (senecio) alkaloids.

1970 • 380 citations

The postnatal growth of the rat lung II. Autoradiography

1974 • 370 citations

An enzymatic protective mechanism against lipid peroxidation damage to lungs of ozone‐exposed rats

1972 • 350 citations

The type II epithelial cell of the lung. I. Method of isolation.

1974 • 313 citations

In Vivo incorporation of choline‐³H, leucine‐³H and galactose‐³H in alveolar type II pneumocytes in relation to surfactant synthesis. A quantitative radioautographic study in mouse by electron microscopy

1972 • 302 citations

Subcellular localization of pulmonary antiotensin-converting enzyme (kininase II)

1975 • 300 citations

Evidence for energy-dependent accumulation of paraquat into rat lung

1974 • 294 citations

Accelerated appearance of pulmonary surfactant in the fetal rabbit.

1971 • 291 citations

Renewal of the terminal bronchiolar epithelium in the rat following exposure to NO2 or O3.

1976 • 289 citations

Drug-Induced Phospholipidoses

1975 • 286 citations

A MORPHOLOGIC AND CYTOCHEMICAL STUDY ON THE GREAT ALVEOLAR CELL

1966 • 270 citations

ISOLATION AND CHARACTERIZATION OF LAMELLAR BODIES AND TUBULAR MYELIN FROM RAT LUNG HOMOGENATES

1973 • 260 citations

Comparison of in vitro drug metabolism by lung, liver, and kidney of several common laboratory species.

1975 • 260 citations

A mechanism of paraquat toxicity in mice and rats

1976 • 253 citations

Lipoperoxidation of Lung Lipids in Rats Exposed to Nitrogen Dioxide

1968 • 251 citations

Derivation of type 1 epithelium from type 2 cells in the developing rat lung.

1975 • 241 citations

Pharmacokinetic function of the pulmonary circulation.

1974 • 216 citations

Oxygen toxicity: augmentation of antioxidant defense mechanisms in rat lung

1976 • 216 citations

Early Response of Lungs to Low Levels of Nitrogen Dioxide

1972 • 216 citations

Early response of lung to low levels of ozone.

1974 • 189 citations

Uptake, metabolism and efflux of 14 C-5-hydroxytryptamine in isolated perfused rat lungs.

1972 • 188 citations

Correlation of paraquat toxicity with tissue concentrations and weight loss of the rat

1972 • 184 citations

PARAQUAT AND RELATED BIPYRIDYLS

1969 • 184 citations

Diffuse Interstitial Lung Disease in Tungsten Carbide Workers

1971 • 183 citations

Acceleration of appearance of pulmonary surfactant in the fetal lamb by administration of corticosteroids.

1970 • 183 citations

Pulmonary Disease Complicating Intermittent Therapy With Methotrexate

1969 • 181 citations

The conversion of pyrrolizidine alkaloids to N-oxides and to dihydropyrrolizine derivatives by rat-liver microsomes in vitro

1971 • 178 citations

Physiologic, biochemical, immunologic and pathologic changes following ozone exposure

1959 • 178 citations

Lung Collagen Composition and Synthesis

1974 • 178 citations

Experimental paraquat poisoning: A histo‐logical and electron‐optical study of the changes in the lung

1971 • 177 citations

The type II epithelial cells of the lung. II. Chemical composition and phospholipid synthesis.

1975 • 174 citations

The connective tissue of lung.

1975 • 173 citations

Reduction of paraquat toxicity by superoxide dismutase

1974 • 165 citations

Phospholipid synthesis in the large pulmonary alveolar cell. Its relation to lung surfactants.

1966 • 165 citations

The pathogenesis and structure of paraquat‐induced pulmonary fibrosis in rats

1974 • 164 citations

Ozone and Lipid Peroxidation

1969 • 164 citations

Studies on the mechanism of the lung toxicity of paraquat: Comparison of tissue distribution and some biochemical parameters in rats and rabbits

1974 • 163 citations

Lipid peroxidation: a possible mechanism for paraquat toxicity.

1975 • 160 citations

Cell Renewal in the Lungs of Rats Exposed to Low Levels of NO₂

1972 • 158 citations

Induction of Pulmonary Edema and Emphysema in Cattle and Goats with 3-Methylindole

1972 • 150 citations

Metabolism and Binding of Aromatic Hydrocarbons in the Lung

1973 • 148 citations

Extracellular lining of bronchioles after perfusion‐fixation of rat lungs for electron microscopy

1971 • 147 citations

The alveolar brush cell in rat lung—a third pneumonocyte

1968 • 147 citations

Alpha‐naphthyl‐thiourea‐induced pulmonary oedema in the rat: A topographical and electron‐microscope study

1972 • 147 citations

Nonrespiratory Functions of Mammalian Lung

1969 • 144 citations

Cytochemistry of pulmonary alveolar epithelial cells.

1968 • 143 citations

Clonal isolation of differentiated rat lung cells

1974 • 142 citations

The preparation of microsomal fractions of rodent respiratory tract and their characterization.

1974 • 139 citations

Accelerated appearance of osmiophilic bodies in fetal lungs following steroid injection.

1971 • 137 citations

The biochemical pathology of liver cell necrosis.

1975 • 136 citations

Toxicity of paraquat to rats and its effect on rat lungs

1970 • 136 citations

Bleomycin-induced interstitial pneumonia in dogs

1971 • 136 citations

Glucocorticoid Receptors in Lung

1973 • 134 citations

Enhancement of oxygen toxicity by the herbicide paraquat.

1973 • 131 citations

Ultrastructure and cytochemistry of Clara cells.

1971 • 128 citations

Ozone interaction with rodent lung. III. Oxidation of reduced glutathione and formation of mixed disulfides between protein and nonprotein sulfhydryls.

1975 • 128 citations

Glucocorticoid Receptors and the Role of Glucocorticoids in Fetal Lung Development

1972 • 126 citations

PHARMACOLOGICAL APPROACHES TO THE ACCELERATION OF FETAL LUNG MATURATION

1975 • 124 citations

Handling of Bioactive Materials by the Lung

1974 • 124 citations

Antioxidants, lipid peroxidation and chemical-induced liver injury.

1973 • 122 citations

Lung Metabolism and Biochemistry

1974 • 118 citations

A comparative study of the hepatic and pulmonary microsomal mixed-function oxidase systems in the rabbit.

1972 • 117 citations

Oxygen pneumonitis in man. Ultrastructural observations on the development of alveolar lesions.

1972 • 116 citations

Basic Pattern of Tissue Repair in Human Lungs Following Unspecific Injury

1974 • 114 citations

Effective Treatment for Paraquat Poisoning in Rats and its Relevance to Treatment of Paraquat Poisoning in Man

1974 • 113 citations

Preparation of lung microsomes and a comparison of the distribution of enzymes between subcellular fractions of rabbit lung and liver.

1972 • 113 citations

Activities of Pentose Shunt and Glycolytic Enzymes in Lungs of Ozone-Exposed Rats

1973 • 112 citations

Biochemical Mechanisms of Paraquat Toxicity

1977 • 112 citations

Pathogenesis and reversibility of the pulmonary lesions of oxygen toxicity in monkeys. I. Clinical and light microscopic studies.

1969 • 111 citations

Compensatory growth of the lung following pneumonectomy.

1973 • 111 citations

Lung Damage in Mice Following Intraperitoneal Injection of Butylated Hydroxytoluene

1972 • 110 citations

In vitro metabolism and microsome-mediated mutagenicity of dialkylnitrosamines in rat, hamster, and mouse tissues.

1975 • 109 citations

Lung Concentric Laminar Organelle

1974 • 109 citations

Glutathione Peroxidase Activity as a Function of Dietary Selenomethionine

1974 • 109 citations

Mitochondrial and other ultrastructural changes in great alveolar cells of oxygen-adapted and poisoned rats.

1969 • 108 citations

NMR-Studies on the molecular basis of drug-induced phospholipidosis—II. Interaction between several amphiphilic drugs and phospholipids

1976 • 106 citations

Ultrastructure of pulmonary bleomycin toxicity

1973 • 103 citations

Xenobiotic accumulation and metabolism by isolated perfused rabbit lungs.

1973 • 102 citations

Pulmonary lesions in rats exposed to ozone. A correlated light and electron microscopic study.

1973 • 100 citations

The formation of granules in the bronchiolar Clara cells of the rat

1974 • 99 citations

Glutathione peroxidase system and lysozyme in rats exposed to ozone or nitrogen dioxide

1974 • 99 citations

The ultrastructure and time sequence of the early stages of paraquat lung in rats

1974 • 98 citations

Lung-toxic furanoterpenoids produced by sweet potatoes (Ipomoea batatas) following microbial infection

1974 • 97 citations

Bleomycin Pulmonary Toxicity

1973 • 96 citations

The rates of radical formation from the dipyridylium herbicides paraquat, diquat, and morfamquat in homogenates of rat lung, kidney, and liver: An inhibitory effect of carbon monoxide

1975 • 93 citations

Oxygen Pneumonitis in Man

1972 • 93 citations

Oxygen poisoning in mice. Ultrastructural and surfactant studies during exposure and recovery.

1970 • 92 citations

Accumulation of 14 C-imipramine in isolated perfused rat lungs.

1972 • 89 citations

Alterations in pulmonary alveoli after a single injection of monocrotaline.

1967 • 89 citations

Ozone interaction with rodent lung: effect on sulfhydryls and sulfhydryl-containing enzyme activities.

1972 • 85 citations

Cigarette smoke: Stimulatory effect on metabolism of 3,4-benzpyrene by enzymes in rat lung

1971 • 85 citations

Lung Changes and Chemotherapeutic Agents in Childhood

1970 • 84 citations

Antioxidants vs lung disease.

1971 • 83 citations

Protective effects of dietary α-tocopherol in rats exposed to toxic levels of ozone and nitrogen dioxide

1973 • 81 citations

Pulmonary metabolism of xenobiotics

1976 • 80 citations

Developmental aspects of hepatic and extrahepatic drug-metabolizing enzyme systems: microsomal enzymes and components in rabbit liver and lung during the first month of life.

1972 • 79 citations

Glucocorticoid Receptors in Lung

1973 • 79 citations

Dietary modification of intestinal and pulmonary aryl hydrocarbon hydroxylase activity*1

1972 • 79 citations

The tissue distribution of the bipyridylium herbicides diquat and paraquat in rats and mice

1973 • 78 citations

The ultrastructure of rat lung changes induced by an anorectic drug (Chlorphentermine)

1972 • 78 citations

Collagen in the human lung. Quantitation of rates of synthesis and partial characterization of composition.

1975 • 78 citations

Role of metabolic activation in the pathogenesis of chemically induced pulmonary disease: mechanism of action of the lung-toxic furan, 4-ipomeanol.

1976 • 77 citations

Changes in the composition of lung lipids and the "turnover" of dipalmitoyl lecithin in experimental alveolar lipo-proteinosis induced by inhaled quartz.

1974 • 76 citations

Factors affecting the postnatal growth of the lung

1939 • 76 citations

Busulphan lung

1969 • 75 citations

The loss of pulmonary surfactant in paraquat poisoning: a model for the study of the respiratory distress syndrome.

1967 • 74 citations

Lung growth after unilateral pneumonectomy: quantitation of collagen synthesis and content.

1975 • 73 citations

Pulmonary oedema induced by ANTU, or by high or low oxygen concentrations in rat--an electron microscopic study.

1972 • 73 citations

The mystery of “non-nucleated plates” in the alveolar epithelium of the lung explained

1971 • 72 citations

Stimulation of DNA Synthesis in Mouse Lung Following Intraperitoneal Injection of Butylated Hydroxytoluene

1974 • 71 citations

Time course of and stimuli to compensatory growth of the lung after pneumonectomy.

1975 • 71 citations

Chlorphentermine-induced lipidosislike ultrastructural alterations in lungs and adrenal glands of several species

1974 • 70 citations

Pulmonary effects of paraquat in the first day after injection

1975 • 70 citations

The mammalian respiratory tract surface. A scanning electron microscopic study.

1972 • 70 citations

Toxicity of Mould-damaged Sweet Potatoes (Ipomoea batatas)

1970 • 70 citations

Preparation and properties of partially purified pulmonary cytochrome P-450 from rabbits.

1976 • 70 citations

Lipid metabolism by rat lung in vitro. Effect of starvation and re-feeding on utilization of [U-14C]glucose by lung slices

1971 • 70 citations

Studies on the mechanism of toxicity and of development of tolerance to the pulmonary toxin, alpha-naphthylthiourea (ANTU).

1976 • 69 citations

Paraquat lung: a reappraisal

1974 • 69 citations

Pulmonary oedema in rats given monocrotaline pyrrole

1972 • 68 citations

Intrapulmonary airway morphology in three species of monkeys: A correlated scanning and transmission electron microscopic study

1975 • 67 citations

Metabolism, production, and release of hormones and mediators in the lung.

1975 • 66 citations

Urethan-induced pulmonary adenoma as a tool for the study of surfactant biosynthesis.

1973 • 66 citations

Fine structure of the lung lesion in a case of paraquat poisoning

1970 • 66 citations

Pulmonary Adenoma of Strain A Mice: An Electron Microscopic Study<xref ref-type="fn" rid="FN2">2</xref>

1968 • 65 citations

The Destruction of Type 2 Pneumocytes by Airborne Influenza PR8-A Virus; Its Effect on Surfactant and Lecithin Content of the Pneumonic Lesions of Mice

1975 • 64 citations

Ultrastructure of pulmonary adenomas in mice.

1962 • 63 citations

Alveolar type 1 cell response to exposure to 0.5 PPM O3 for short periods

1974 • 63 citations

Preparation and partial characterization of a lamellar body fraction from rat lung

1972 • 62 citations

Electron microscopy of Crotalaria pulmonary hypertension

1969 • 62 citations

Adaptive growth of the lung following pneumonectomy in rats.

1974 • 62 citations

Endothelial regeneration as a marker of the differential vascular responses in oxygen-induced pulmonary edema.

1974 • 62 citations

Clonal isolation of epithelial cells from mouse lung adenoma.

1975 • 61 citations

Identification of Cells Labeled with Tritiated Thymidine in the Pulmonary Alveolar Walls of the Mouse^1,2,3

1969 • 61 citations

LOCALIZATION OF PHOSPHATIDIC ACID PHOSPHATASE ACTIVITY IN GRANULAR PNEUMONOCYTES

1972 • 60 citations

Ozone interactions with lung tissue

1976 • 59 citations

Autoradiographical and morphological evidence for apocrine secretion of dipalmitoyl lecithin in the terminal bronchiole of mouse lung

1973 • 58 citations

Oxygen Effect on Lung Cells

1971 • 56 citations

Electron microscopy of desquamative interstitial pneumonia

1969 • 56 citations

Cellular dynamics and lipid metabolism in the lung.

1973 • 56 citations

Comparison of microsomal drug hydroxylation in lung and liver of various species.

1970 • 56 citations

Drug-induced phospholipidosis

1974 • 55 citations

A comparative ultrastructural study of the effects of chlorphentermine and triparanol in rat lung and adrenal gland

1972 • 55 citations

An ultrastructural study of the pulmonary lesion induced by pyrrole derivatives of the pyrrolizidine alkaloids

1970 • 54 citations

Lung Collagen Heterogeneity

1974 • 54 citations

Cellular proliferation induced in the lung by cadmium aerosol.

1975 • 54 citations

A COMPARATIVE CYTOCHEMICAL STUDY OF MICROBODIES (PEROXISOMES) IN GREAT ALVEOLAR CELLS OF RODENTS, RABBIT AND MONKEY

1972 • 54 citations

The bronchiolar epithelium in cigarette smokers. Observations with the scanning electron microscope.

1975 • 54 citations

Effects of cigarette smoking on aryl hydrocarbon hydroxylase activity in lungs and tissues of inbred mice.

1975 • 53 citations

Ultrastructure of lung lesions produced by ingested chemicals. I. Effect of the herbicide paraquat on mouse lung.

1971 • 53 citations

Pulmonary histiocytosis simulating desquamative interstitial pneumonia in rats receiving oral iprindole

1972 • 53 citations

Mixed-function oxidases and the alveolar macrophage

1972 • 53 citations

Serum Lactic Dehydrogenase Activity and Diffuse Interstitial Pneumonitis

1968 • 53 citations

Effects of Nitrogen Dioxide Inhalation on Germfree Mouse Lung

1969 • 53 citations

Electron microscopy of endothelial and epithelial components of the lungs: correlations of structure and function.

1973 • 52 citations

Oxygen and Lung Fibrosis

1975 • 51 citations

Hyperplasia of Type 2 Pneumocytes and Nitrogen Dioxide (10 ppm) Exposure

1971 • 51 citations

Immunological study of lung development in the mouse embryo

1975 • 49 citations

Depression of pulmonary 5-hydroxytryptamine uptake by metabolic inhibitors

1975 • 49 citations

Oxygen Toxicity in the Newborn Lung: Reversal of Inhibition of DNA Synthesis in the Mouse

1976 • 48 citations

Busulfan-induced pulmonary disease. Report of a case and review of the literature.

1970 • 48 citations

Exploitable Biochemical Approaches for the Evaluation of Toxic Lung Damage

1975 • 48 citations

Immunoelectron microscopic and immunochemical demonstrations of serum proteins in the alveolar lining material of the rat lung.

1976 • 48 citations

Isolation of inclusion bodies from rabbit lung parenchyma

1972 • 47 citations

Distribution, excretion, and binding of radioactivity in the rat after intraperitoneal administration of the lung-toxic furan, 614C94-ipomeanol*1

1975 • 47 citations

Ruminal and plasma concentrations of 3-methylindole associated with tryptophan-induced pulmonary edema and emphysema in cattle.

1975 • 47 citations

Oxidative Enzymes of the Interalveolar Septum of the Rat

1965 • 47 citations

Induction of increased benzpyrene hydroxylase activity by 2-phenylbenzothiazoles and related compounds.

1968 • 46 citations

Acyltransferases and the biosynthesis of pulmonary surfactant lipid in adenoma alveolar type II cells

1975 • 46 citations

Resistance and susceptibility to oxygen toxicity by cell types of the gas-blood barrier of the rat lung.

1970 • 45 citations

Pulmonary intra-alveolar histiocytosis induced by drugs

1973 • 45 citations

Lung growth in mice after a single dose of butylated hydroxytoluene

1975 • 45 citations

The lung in relation to vasoactive hormones.

1973 • 45 citations

Enzymatic conjugation of foreign chemical compounds by rabbit lung and liver.

1974 • 44 citations

Alterations in cell proliferation in mouse lung following urethane exposure. 3. Effects of chronic exposure on type 2 alveolar epithelial cell.

1972 • 44 citations

Morphologic and Ultrastructural Changes in the Lungs of Animals During Acute Exposure to Ozone

1974 • 43 citations

Biochemical parameters of BHT-induced cell growth in mouse lung

1976 • 43 citations

Pulmonary effects of the herbicide paraquat studied 3 days after injection in rats.

1973 • 43 citations

Electron microscopy of chlorphentermine lung

1973 • 43 citations

The intracellular site of surfactant synthesis

1973 • 42 citations

Pulmonary Alveolar Reaction to Nickel Carbonyl

1968 • 42 citations

BIOCHEMICAL DISTURBANCES IN LIVER INJURY

1969 • 41 citations

Effect of pregnancy or treatment with cetain steroids on N,N-dimethylaniline demethylation and N-oxidation by rabbit liver or lung microsomes.

1975 • 41 citations

Receptors for glucocorticoids in lung tissue

1973 • 41 citations

Ultrastructural changes of Clara and type II alveolar cells in adrenalin-induced pulmonary edema in mice.

1971 • 41 citations

Metabolism of Alveolar Cells: Histochemical Evidence and Relation to Pulmonary Surfactant

1966 • 41 citations

Hyperoxia: Influence on Lung Mechanics and Protein Synthesis

1973 • 41 citations

Antioxidants vs Lung Disease

1971 • 41 citations

Pentose pathway and production of reduced nicotinamide adenine dinucleotide phosphate. A mechanism that may protect lungs from oxidants.

1973 • 40 citations

Energy utilization by the lung

1974 • 40 citations

A comparative study of in vivo RNA and protein synthesis in rat liver and lung.

1972 • 40 citations

Drug-induced foam cell reactions in rats

1974 • 40 citations

QUANTITATIVE ASPECTS OF OXYGEN TOXICITY IN THE NEWBORN: INHIBITION OF LUNG DNA SYNTHESIS IN THE MOUSE

1972 • 39 citations

Effect of hypoxia on incorporation of glucose carbons into lipids by isolated rat lung

1974 • 39 citations

Morphometric evaluation of pulmonary lesions in rats exposed to ozone.

1973 • 38 citations

Effects of chlorphentermine on the rat lung

1973 • 38 citations

Distribution, subcellular localization, and product inhibition of dihydroorotate oxidation in the rat

1973 • 38 citations

Granular pneumocytes. Electron microscopic radioautographic evidence of intracellular protein transport.

1972 • 38 citations

Effects of short-term ozone exposure on lung mitochondrial oxidative and energy metabolism

1974 • 37 citations

A Note on Differentiation and Divisibility of Alveolar Epithelial Cells

1974 • 37 citations

Ultrastructural changes in the alveolar epithelium in response to Freund's adjuvant.

1971 • 37 citations

Acute Effects of Ozone on Cat Lungs

2015 • 37 citations

Inhibition of induction of benzpyrene hydroxylase by nickel carbonyl.

1967 • 36 citations

Electron Transport Systems of Lung Microsomes and Their Physiological Functions: I. Intracellular Distribution of Oxidative Enzymes in Lung Cells

1971 • 36 citations

Oxygen Toxicity

1973 • 35 citations

Dispersal of Rabbit Lung into Individual Viable Cells: A New Model for the Study of Lung Metabolism

1972 • 35 citations

ULTRASTRUCTURE OF THE ALVEOLAR WALL IN EXPERIMENTAL PARAQUAT POISONING

1972 • 35 citations

Protein synthesis in lung: influence of starvation on amino acid incorporation into protein.

1972 • 35 citations

Alveolar Injury in Acute Carbon Tetrachloride Intoxication

1971 • 35 citations

Morphological and Biochemical Assessment of Papain-Induced Emphysema

1971 • 34 citations

The effect of dietary protein and fat on the activity of aryl hydrocarbon hydroxylase in rat liver, kidney and lung

1973 • 34 citations

Enzyme Alterations Following Nitrogen Dioxide Exposure

1967 • 34 citations

Drug-Induced Lung Disease

1973 • 34 citations

Oxygen-induced changes in pulmonary phospholipids in the rat

1975 • 34 citations

Acute Pathological Reactions to Administration of Nickel Carbonyl

1967 • 33 citations

COMPENSATORY HYPERTROPHY OF THE LUNG AFTER UNILATERAL PNEUMECTOMY

1928 • 33 citations

Oxygen Pneumonitis in Man

1974 • 33 citations

Alkylation of Nucleic Acids of Rat Liver and Lung by Deuterated <italic>N</italic>-Nitrosodiethylamine <italic>In Vivo</italic><xref ref-type="fn" rid="FN1">2</xref>

1971 • 33 citations

Cytochemically detected alterations of lung acid phosphatase reactivity following ozone exposure.

1973 • 33 citations

Lysosomal aryl sulphatase in pulmonary alveolar cells

1968 • 32 citations

Effect of ozone on benzpyrene hydroxylase activity in the Syrian golden hamster.

1971 • 32 citations

Increased Lysosomal Enzymes in Lungs of Ozone-Exposed Rats

1972 • 32 citations

Ozone interaction with rodent lung. II. Effects on oxygen consumption of mitochondria.

1973 • 32 citations

Lipid metabolism by rat lung in vitro. Utilization of citrate by normal and starved rats

1972 • 32 citations

Superoxide independence of paraquat toxicity in Escherichia coli

1976 • 32 citations

Reparative changes following pulmonary cell injury. Ultrastructural, cytodynamic, and surfactant studies in mice after oxygen exposure.

1971 • 32 citations

The Role of the Portal of Entry in Inhibition of Tumorigenesis

2015 • 31 citations

The inhibition of enzymes related to pulmonary fatty acid and phospholipid synthesis by dietary deprivation in the rat

1975 • 31 citations

Animal model of human disease. Pulmonary alveolar lipo-proteinosis. Animal model: Silica-induced pulmonary alveolar lipo-proteinosis.

1975 • 31 citations

Drug-Induced Foam Cell Reactions in Rats, II. Chemical Analysis of Lipids Stored in Lungs and Foam Cells after Treatment with Chlorphentermine, 5-[p-(Fluoren-9-ylidenemethyl)phenyl]-2-piperidineethanol (RMI 10.393) and 1-Chloramitriptyline

1975 • 31 citations

On the origin of the membranous intraalveolar material in pulmonary alveolar proteinosis

1974 • 31 citations

Pores of Kohn

1972 • 30 citations

Characterization of a rat lung microsomal fraction obtained by sepharose 2B ultrafiltration.

1975 • 30 citations

Endocrine role of the lung in disease

1974 • 30 citations

Acute and Chronic Exposures to Nitrogen Dioxide

1965 • 30 citations

The ultrastructure of the paraquat lung lesion in the rat

1973 • 30 citations

Nickel carbonyl inhibition of RNA synthesis by a chromatin-RNA polymerase complex from hepatic nuclei.

1970 • 30 citations

Fine structural alterations in the lungs of iprindole‐treated rats

1974 • 29 citations

Effects of Nitrogen Dioxide on Lactic Dehydrogenase Isozymes

1967 • 29 citations

Pulmonary toxicity due to bleomycin. Report of a case.

1973 • 29 citations

THE BIOCHEMICAL LESION AND ITS HISTORICAL DEVELOPMENT

1969 • 28 citations

Metabolism of the phenothiazine drug perazine by liver and lung microsomes from various species

1971 • 28 citations

Isolation and Identification of Type 2 Alveolar Epithelial Cells

1975 • 28 citations

Augmentation of mitochondrial oxidative metabolish in lung tissue during recovery of animals from acute ozone exposure

1974 • 28 citations

Synthetic Compounds with Toxic Properties similar to those of Pyrrolizidine Alkaloids and their Pyrrolic Metabolites

1971 • 28 citations

Metabolism of foreign compounds by alveolar macrophages of rabbits

1972 • 28 citations

Pulmonary alveolar proteinosis developing from desquamative interstitial pneumonia in long term toxicity studies of iprindole in the rat

1973 • 28 citations

Morphometric Evaluation of Ultrastructural Changes in Type II Alveolar Cells of Rat Lung Produced by Bromhexine

1971 • 27 citations

Hydrogen Peroxide in Erythrocytes

1973 • 27 citations

The development of the human type II pneumocyte

1975 • 26 citations

Induction of aryl hydrocarbon hydroxylase in the lungs of mice in response to cigarette smoke

1973 • 26 citations

Decrease in rabbit lung microsomal cytochrome P-450 levels following ozone exposure.

1975 • 26 citations

Protein synthesis and secretion by lung.

1970 • 26 citations

Glucose metabolism by isolated rat lung cells

1973 • 26 citations

Pulmonary aryl hydrocarbon hydroxylase: Tobacco smoke-exposed guinea pigs*1

1977 • 25 citations

Animal model: Oxygen toxicity in nonhuman primates.

1974 • 25 citations

Nucleic acid synthesis and mitotic activity during development of compensatory hypertrophy of the lung in rats

1967 • 25 citations

The composition of lung lipids after poisoning with paraquat.

1970 • 25 citations

Effect of PR-8 Viral Respiratory Infection on Benzo[a] pyrene Hydroxylase Activity in BALB/c Mice2

1973 • 25 citations

Influence of starvation on the lung: effect on glucose and palmitate utilization

1975 • 25 citations

Effect of tobacco, marijuana and benzo[a]pyrene on aryl hydrocarbon hydroxylase in hamster lung

1972 • 24 citations

Acute Kinetic Response and Renewal of the Alveolar Epithelium following Injury by Nitrogen Dioxide

1974 • 24 citations

The Granular Type II Pneumonocyte and Lung Antioxidant Defense

1974 • 24 citations

Alteration of cellular and acellular alveolar and bronchiolar walls produced by hypocholesteremic drug AY9944.

1972 • 24 citations

Characterization of cell-free synthesis of collagen by lung polysomes in a heterologous system.

1975 • 24 citations

The effect of ozone exposure in vivo on the appearance of lung tissue lipids in the endobronchial lavage of rabbits

1973 • 24 citations

The effects of exercise training and denervation on the morphology of intrafusal muscle fibers

1971 • 24 citations

Metabolic factors affecting protein synthesis by lung in vitro.

1971 • 23 citations

In vivo protein secretion by lung. Evidence for active secretion and interspecies differences.

1975 • 23 citations

An EPR study of structural perturbations induced by 3-methylindole in the protein and lipid regions of erythrocyte membranes

1975 • 22 citations

Amino acid incorporation into protein of a surface-active lung fraction.

1973 • 22 citations

The blood-air barrier in desquamative interstitial pneumonia (D.I.P.)

1969 • 22 citations

Nuclear Magnetic Resonance Studies of Lecithin-Skatole Interaction

1974 • 22 citations

Organ-Specific DNA Damage Induced in Mice by the Organotropic Carcinogens 4-Nitroquinoline 1-Oxide and DimethyInitrosamine

1975 • 21 citations

Hypertrophy of Alveolar Wall Cells Secondary to an Air Pollutant

1973 • 21 citations

Alveolar Wall Cells of the Guinea Pig

1972 • 21 citations

Reaction of cultured adult and fetal lung to prednisolone and thyroxine.

1975 • 21 citations

Histochemically detected enzymatic alterations in rat lung exposed to ozone

1973 • 21 citations

Use of thermolysin for the dissociation of lung tissue into cellular components.

1975 • 21 citations

Ver�nderungen der Lungenalveolen bei der Maus nach chronischer Exposition mit Ozon in niedriger Konzentration

1973 • 20 citations

Damage and repair of DNA in various tissues of the rat induced 4-nitroquinoline 1-oxide.

1975 • 20 citations

Palmitate-14C uptake by rat lung effect of altered gas tensions

1968 • 19 citations

Experimental acute alveolar injury in the dog. Morphologic--mechanical correlations.

1976 • 19 citations

Effect of ethanol on phospholipid metabolism by the rat lung

1975 • 19 citations

Glucocorticoid receptors in lung. Mechanism of specific glucocorticoid uptake by fetal rabbit lung nuclei.

1975 • 19 citations

Comparison of the subacute effects of cadmium exposure upon nucleic acid, cyclic adenosine 3′, 5′-monophosphate and polyamine metabolism in lung and kidney cortex

1976 • 19 citations

Effects of ozone exposure on the lungs and the erythrocytes of rats and monkeys: relative biochemical changes.

1975 • 18 citations

Influence of Pollutant Gases on Benzpyrene Hydroxylase Activity

1972 • 18 citations

Alveolar cell hyperplasia in the lungs of smoking dogs

1974 • 18 citations

Nickel carbonyl inhibition of induction of aminopyrine demethylase activity in liver and lung.

1970 • 18 citations

Response of lactic acid dehydrogenase-positive alveolar cells in the lungs of guinea pigs exposed to nitric oxide.

1967 • 18 citations

Adaption to Hyperoxia

1974 • 18 citations

Metal shifts as early indicators of response from low-grade pulmonary irritation

1966 • 18 citations

Collagen metabolism in rat lungs during chronic intermittent exposure to oxygen.

1975 • 18 citations

The Isolation and Characterization of The Lamellar Body of Bovine Lung

1971 • 17 citations

Solubilization and partial purification of cytochrome P-450 from rat lung microsomes

1975 • 17 citations

Experimental lung injury. I. Bacterial pneumonia: ultrastructural, autoradiographic and histochemical observations.

1973 • 17 citations

The action of paraquat on the incorporation of palmitic acid into dipalmitoyl lecithin in mouse lungs.

1972 • 17 citations

Effects of 100% oxygen on cell division in lung alveoli of squirrel monkeys.

1975 • 16 citations

Observation of the secretion on the surface of the bronchioles with the scanning electron microscope.

1975 • 16 citations

The fate of intratracheally installed benzo(a)pyrene in the isolated perfused rat lung of both control and 20-methylcholanthrene pretreated rats.

1976 • 16 citations

Enzymatic Activity in Rat Lungs. Some Changes with Exposure to 1 ATM Oxygen

1975 • 16 citations

Studies on lung tumours III. oxidative metabolism of dimethylnitrosamine by rodent and human lung tissue

1975 • 16 citations

Induction of aryl hydrocarbon hydroxylase in rat lung by marijuana smoke

1975 • 16 citations

Pulmonary Lesions Induced by Chronic Exposure to Ozone

1974 • 16 citations

The role of the granular pneumonocyte in surfactant metabolism an autoradiographic study.

1969 • 16 citations

Hyperoxia: A Stereologic Ultrastructural Examination of Its Influence on Cytoplasmic Components of the Pulmonary Granular Pneumocyte

1973 • 15 citations

OXYGEN TOXICITY INTRODUCTION TO A PROTECTIVE ENZYME

1975 • 15 citations

Cloforex-induced pulmonary changes in rats.

1972 • 15 citations

PULMONARY GRANULAR PNEUMOCYTES

1973 • 15 citations

The metabolism of isolated pneumocytes from rabbit lung

1968 • 15 citations

Effect of AY-9944, a cholesterol biosynthesis inhibitor, on fetal lung development and on the development of type II alveolar epithelial cells.

1973 • 15 citations

Collagen Biosynthesis in Rat Lungs during Exposure to Asbestos

1971 • 14 citations

Isozymes of lactate dehydrogenase during beryllium carcinogenesis in the rat.

1967 • 14 citations

Metabolism of environmental pollutants by the isolated perfused lung.

1976 • 14 citations

Fatty change of the granular pneumocyte in CCl4 intoxication.

1966 • 14 citations

Effect of paraquat on the biosynthesis of deoxyribonucleic acid, ribonucleic acid and protein in the rat

1975 • 14 citations

Studies on the pathological biochemistry of lung parenchyma in acute paraquat poisoning.

1974 • 13 citations

Serial electron and light microscopic studies on the dog lung in chronic experimental pulmonary edema.

1970 • 13 citations

Recent advances in molecular pathology isotopic analysis of metabolic systems

1974 • 13 citations

Isolation And Identification op Pulmonary Lamellar Bodies from Guinea Pigs

1973 • 13 citations

Mechanisms of oxygen inhibition of pulmonary surfactant synthesis.

1974 • 13 citations

The effects of diethylnitrosamine on ribonucleic acid and protein synthesis in the liver and lung of the Syrian golden hamster

1973 • 13 citations

Origin of the pulmonary alveolar macro‐phage studied in the iprindole‐treated rat

1972 • 13 citations

Beryllium Effects on Aryl Hydrocarbon Hydroxylase in Rat Lung

1973 • 12 citations

Histological changes of terminal bronchioles in rats during the exposure to nitrogen dioxide

1975 • 12 citations

The Effects of 3-Methylindole on Hemolysis, Transport of 22Na+, and ATPase Activities of Bovine Erythrocytes

1975 • 12 citations

Toxic effects of hydroperoxide injections on rat lung. A light microscopical and ultrastructural study.

1976 • 12 citations

Changes in Activities of Respiratory Enzymes in Lungs of Guinea-Pigs Exposed to Silica Dust

1963 • 12 citations

Influence of cycloheximide on the lung

1975 • 11 citations

Effects of biliary obstruction on pulmonary ultrastructure in the rat.

1972 • 11 citations

Paraquat poisoning as an experimental model of the idiopathic respiratory distress syndrome.

1973 • 10 citations

Protein Transport by Lung

1974 • 10 citations

Induction of pulmonary aryl hydrocarbon hydroxylase by marijuana.

1972 • 10 citations

An inhibitor of cholesterol biosynthesis and the alveolar macrophages.

1966 • 10 citations

Recent advances in molecular pathology

1974 • 10 citations

Isolation of enzymatically active nuclei from epithelial cells of the trachea.

1971 • 9 citations

IMPORTANCE OF OXYGEN AND OF PULMONARY ALVEOLAR SURFACTANT IN LUNG INJURY BY PARAQUAT

1977 • 9 citations

Qualitative and quantitative aspects of the biosynthesis of ribonucleic acid and of protein in the liver and the lung of the Syrian golden hamster

1973 • 9 citations

Hyperoxia and Lung Metabolism

1974 • 9 citations

Interstitial pulmonary edema following bromocarbamide intoxication.

1974 • 9 citations

Binding of Chemical Carcinogens in the Lung 2

1974 • 9 citations

Ultrastrukturelle und lichtmikroskopische Befunde bei drei protrahiert tödlich verlaufenen Paraquatvergiftungen

1974 • 9 citations

Effect of hyperbaric oxygen on lipid peroxidation in the lung.

1971 • 8 citations

Lung phospholipids: Biochemical and histologic changes induced by the cholesterol biosynthesis inhibitor AY-9944

1967 • 8 citations

II. Effect of Ozone Inhalation on Nadide Phosphate Levels in Tracheal Mucosa

1971 • 8 citations

Common Oxidant Lesion of Mitochondrial Redox State Produced by Nitrogen Dioxide, Ozone, and High Oxygen In Alveolar Macrophages

1974 • 8 citations

Effects of intermittent hyperbaric oxygen on guinea pig lung elastin and collagen

1976 • 8 citations

An Experimental Approach to Study the Toxicity of Nonparticulate Air Pollutants

1971 • 7 citations

Biochemical Study of Nuclei Isolated From Normal Lung and From Lung Tumors. II. Nuclear RNAs of Low Molecular Weight<xref ref-type="fn" rid="FN1">2</xref>

1971 • 7 citations

Morphological alterations in type II alveolar cells in essential fatty acid deficiency

1975 • 7 citations

The Clara cells and the pulmonary surfactant system. Light and electron microscopic studies on the function of Clara cells.

1973 • 7 citations

Phospholipid Metabolism in Lung Adenomas: A Model of Surface Active Material Synthesis

1975 • 7 citations

Effects of Nitrogen Dioxide and 3-Methylcholanthrene on Pulmonary Enzymes

1975 • 7 citations

Oxygen Toxicity in the Newborn Guinea Pig Lung

1971 • 7 citations

Protein synthesis in lung: recovery from exposure to hyperoxia.

1973 • 7 citations

Morphologie der Alveolaroberfläche

1971 • 7 citations

Alterations in the LDH Isoenzymes of Rat Bronchial Mucosa during Chemical Carcinogenesis

1972 • 6 citations

The Distribution and Fate of ¹⁴C‐Cloforex in the Lung of the Rat

1973 • 6 citations

Metabolism of Vasoactive Substances in the Lung : Change of Metabolism and its Significance in Rabbits with Experimental Pneumonitis

1975 • 6 citations

Inhaled Irradiated Terphenyls

1973 • 6 citations

PULMONARY RESPONSE OF MICE EXPOSED TO SYNTHETIC SMOG

1972 • 5 citations

Increased susceptibility to pulmonary oxygen toxicity after cholesterol biosynthesis inhibition.

1975 • 5 citations

The in vivo effects of quartz and carbon dusts on the activity of cytochrome C oxidase and the DNA and RNA content of lung tissue.

1968 • 5 citations

The Lung as a Chemical Filter

1974 • 5 citations

Stereologic Evaluation of Granular Pneumocyte Lamellar Bodies in Different Species

1975 • 5 citations

The Acute Toxicity of Reactor Polyphenyls on the Lung

1969 • 5 citations

Die Pathogenese der Paraquat-Lunge

1974 • 5 citations

Biochemical Study of Nuclei Isolated From Normal Lung and Lung Tumors. I. Isolation of Nuclei and Characterization of Nuclear RNA<xref ref-type="fn" rid="FN2">2</xref>

1971 • 4 citations

Effects of the carcinogen urethane on nuclear RNA polymerase activities

1975 • 4 citations

Alcohol-induced pulmonary changes in rats

1975 • 4 citations

Effects of prednisolone on the differentiation of mouse lung adenomas in culture.

1976 • 4 citations

Intraspecies differences in lung metabolism and granular pneumocyte mitochondria

1975 • 4 citations

Special susceptibility of Clara cells of the murine terminal bronchiole to 4-nitroquinoline 1-oxide: an electron microscopic observation.

1973 • 4 citations

Effect of exposure to quartz dust in vivo on pentose cycle activity in guinea pig lung

1973 • 4 citations

Adaptation to hyperoxia.

1945 • 3 citations

[Lung lesions induced by oxygen or ozone in rats].

1974 • 3 citations

Pulmonary oxygen toxicity in hemorrhagic shock.

1969 • 3 citations

Effect of feeding and lighting on the regulation of aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in the liver, small intestine, and lung of mice.

1975 • 3 citations

Protein synthesis of monkey lung subcellular fractions after exposure to silica in vivo

1974 • 2 citations

Density Distribution of Rat Lung Cells

1975 • 2 citations

Prolonged Glucocorticoid Treatment in the Rat: Effects on Pulmonary Morphology, Ultrastructure and Elastic Properties

1975 • 2 citations

Effect of cirrhosis on pulmonary fibrogenesis caused by silica dust in rats

1975 • 1 citations

Workshop on Possible Pharmacologic Mechanisms for Enhancement of Lung Maturation

1974 • 1 citations