Pulmonary aryl hydrocarbon hydroxylase: Tobacco smoke-exposed guinea pigs*1

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 1,691 citations

Aryl Hydrocarbon Hydroxylase Inducibility and Bronchogenic Carcinoma

1973 • 601 citations

Benzpyrene hydroxylase activity in the gastrointestinal tract.

1962 • 328 citations

Genetic Expression of Aryl Hydrocarbon Hydroxylase Activity

1974 • 326 citations

Polychlorinated Biphenyls: A New Type of Inducer of Cytochrome P-448 in the Liver

1973 • 273 citations

Penetration of the respiratory epithelium of guinea pigs following exposure to cigarette smoke.

1974 • 215 citations

Liver and brain mitochondria

1957 • 160 citations

Microsomal hydroxylases: induction and role in polycyclic hydrocarbon carcinogenesis and toxicity.

1972 • 119 citations

Relationships Between Aryl Hydrocarbon Hydroxylase Inducibility and Sensitivity to Chemically Induced Subcutaneous Sarcomas in Various Strains of Mice23

1973 • 99 citations

Evidence of a Genetic Relationship Between Susceptibility to 3-Methylcholanthrene-Induced Subcutaneous Tumors and Inducibility of Aryl Hydrocarbon Hydroxylase2

1973 • 98 citations

Cigarette smoke: Stimulatory effect on metabolism of 3,4-benzpyrene by enzymes in rat lung

1971 • 85 citations

Effect of exposure to cigarette smoke on the metabolism of benzo6a9pyrene and acetophenetidin by lung and intestine of rats

1972 • 57 citations

Effects of cigarette smoking on aryl hydrocarbon hydroxylase activity in lungs and tissues of inbred mice.

1975 • 53 citations

Induction of aryl hydrocarbon hydroxylase in the lungs of mice in response to cigarette smoke

1973 • 26 citations

Effect of tobacco, marijuana and benzo[a]pyrene on aryl hydrocarbon hydroxylase in hamster lung

1972 • 24 citations

Induction of aryl hydrocarbon hydroxylase in rodent lung by cigarette smoke: A potential short-term bioassay

1976 • 23 citations

Nicotine Inhibition of the Metabolism of 3,4-Benzopyrene, a Carcinogen in Tobacco Smoke

1974 • 19 citations

Induction of aryl hydrocarbon hydroxylase in rat lung by marijuana smoke

1975 • 16 citations

Beryllium Effects on Aryl Hydrocarbon Hydroxylase in Rat Lung

1973 • 12 citations

Induction of pulmonary aryl hydrocarbon hydroxylase by marijuana.

1972 • 10 citations

Activation of 2-aminoanthracene to mutagenic intermediates by guinea pig kidney microsomal enzymes following tobacco smoke inhalation

1977 • 7 citations