Cellular Promoters Incorporated into the Adenovirus Genome: Effects of Viral Regulatory Elements on Transcription Rates and Cell Specificity of Albumin and β-Globin Promoters

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

1985 • 805 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Specific DNA binding of GAL4, a positive regulatory protein of yeast

1985 • 767 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Cell-Specific Expression of the Rat Insulin Gene: Evidence for Role of Two Distinct 5′ Flanking Elements

1985 • 698 citations

Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes

1983 • 659 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements

1985 • 588 citations

Enhancer elements

1983 • 576 citations

The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element

1983 • 467 citations

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

1984 • 458 citations

The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) sites

1978 • 409 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Adenovirus E1a proteins repress transcription from the SV40 early promoter

1985 • 366 citations

A genetic analysis of extinction: Trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells

1984 • 365 citations

Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection.

1983 • 295 citations

The 2.2 kb E1b mRNA of human Ad12 and Ad5 codes for two tumor antigens starting at different AUG triplets

1981 • 290 citations

Primary Structure of the Saccharomyces cerevisiae GAL4 Gene

1984 • 276 citations

cis and trans activation of globin gene transcription in transient assays.

1983 • 257 citations

Dependence of liver-specific transcription on tissue organization.

1985 • 230 citations

Multiple regulatory elements in the intergenic region between the alpha-fetoprotein and albumin genes.

1986 • 205 citations

A dimer of AraC protein contacts three adjacent major groove regions of the araI DNA site.

1985 • 197 citations

HeLa Cell β-Tubulin Gene Transcription Is Stimulated by Adenovirus 5 in Parallel with Viral Early Genes by an E1a-Dependent Mechanism

1984 • 187 citations

Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis

1984 • 186 citations

Autoregulation plus upstream positive and negative control regions associated with transcriptional activation of the mouse P₁450 gene

1985 • 174 citations

Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection.

1984 • 167 citations

Transcriptional Activation and Subsequent Control of the Human Heat Shock Gene During Adenovirus Infection

1983 • 131 citations

Accurate transcription initiation on a purified mouse β-globin DNA fragment in a cell-free system

1980 • 126 citations

E1A Transcription Induction: Enhanced Binding of a Factor to Upstream Promoter Sequences

1986 • 116 citations

Liver-Specific RNA Metabolism in Hepatoma Cells: Variations in Transcription Rates and mRNA Levels

1985 • 91 citations

Sequence-Independent Autoregulation of the Adenovirus Type 5 E1A Transcription Unit

1985 • 86 citations

Cellular promoters incorporated into the adenovirus genome: cell specificity of albumin and immunoglobulin expression.

1986 • 77 citations

Dependence of Liver-Specific Transcription on Tissue Organization

1985 • 72 citations

Transcription control region within the protein-coding portion of adenovirus E1A genes.

1984 • 48 citations

Cellular Promoters Incorporated into the Adenovirus Genome: Cell Specificity of Albumin and Immunoglobulin Expression

1986 • 32 citations

Adenovirus E1A protein activation of an integrated viral gene.

1984 • 25 citations