Ligation-Mediated PCR for Analysis of Oxidative DNA Damage

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DNA damage by oxygen‐derived species Its mechanism and measurement in mammalian systems

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An introduction to free radical biochemistry

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In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR

1989 • 972 citations

Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair

1986 • 933 citations

Role of oxygen free radicals in carcinogenesis and brain ischemia

1990 • 885 citations

Sites and thermodynamic quantities associated with proton and metal ion interaction with ribonucleic acid, deoxyribonucleic acid, and their constituent bases, nucleosides, and and nucleotides

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A computer program for choosing optimal oligonudeotides for filter hybridization, sequencing andin vitroamplification of DNA

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Oxidative damage to DNA in mammalian chromatin

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Chemical determination of free radical-induced damage to DNA

1991 • 523 citations

A site-specific mechanism for free radical induced biological damage: The essential role of redox-active transition metals

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Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide

1991 • 487 citations

Oxidative mechanisms in carcinogenesis

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Mitochondrial Production of Superoxide Radical and Hydrogen Peroxide

1977 • 415 citations

Genomic Sequencing and Methylation Analysis by Ligation Mediated PCR

1989 • 408 citations

The enzymology of apurinic/apyrimidinic endonucleases

1990 • 378 citations

Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: The role of dna base damage

1990 • 364 citations

Hydroxyl free radical is not the main active species in site-specific DNA damage induced by copper (II) ion and hydrogen peroxide

1989 • 354 citations

New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase.

1994 • 337 citations

Ap endonucleases and dna glycosylases that recognize oxidative dna damage

1988 • 254 citations

Damage to the DNA bases in mammalian chromatin by hydrogen peroxide in the presence of ferric and cupric ions

1991 • 240 citations

Reactions of low-valent transition-metal complexes with hydrogen peroxide. Are they "Fenton-like" or not? 1. The case of Cu+aq and Cr2+aq

1988 • 239 citations

Site-specific Oxidative DNA Damage at Polyguanosines Produced by Copper Plus Hydrogen Peroxide

1989 • 239 citations

Chromatin differences between active and inactive X chromosomes revealed by genomic footprinting of permeabilized cells using DNase I and ligation-mediated PCR.

1991 • 195 citations

Formation of 8-hydroxydeoxyguanosine, hydroxyl free radical adduct of DNA in granulocytes exposed to the tumor promoter, tetradeconylphorbolacetate

1986 • 192 citations

Effects of Glutathione and Chelating Agents on Copper-Mediated DNA Oxidation: Pro-oxidant and Antioxidant Properties of Glutathione

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New trends in photobiology

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The role and mechanism of metal ions and their complexes in enhancing damage in biological systems or in protecting these systems from these systems from the toxicity of O2−

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Involvement of free radicals in ageing: a consequence or cause of senescence

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Hydroxyl free radical mediated formation of 8-hydroxyguanine in isolated DNA

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New trends in photobiology

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Covalent modification of guanine bases in double-stranded DNA. The 1.2-A Z-DNA structure of d(CGCGCG) in the presence of CuCl2.

1991 • 140 citations

Covalent modification of guanine bases in double-stranded DNA. The 1.2-A Z-DNA structure of d(CGCGCG) in the presence of CuCl2.

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Structure of binary complexes of mono- and polynucleotides with metal ions of the first transition group

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PCR protocols: current methods and applications.

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Chemical nature of in vivo DNA base damage in hydrogen peroxide-treated mammalian cells

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Copper-catalyzed dna damage by ascorbate and hydrogen peroxide: Kinetics and yield

1987 • 115 citations

Cupric ion/ascorbate/hydrogen peroxide-induced DNA damage: DNA-bound copper ion primarily induces base modifications

1996 • 103 citations

Base-specific binding of copper(II) to Z-DNA. The 1.3-A single crystal structure of d(m5CGUAm5CG) in the presence of CuCl2.

1991 • 100 citations

Base-specific binding of copper(II) to Z-DNA. The 1.3-A single crystal structure of d(m5CGUAm5CG) in the presence of CuCl2.

1991 • 93 citations

Mapping of Copper/Hydrogen Peroxide-induced DNA Damage at Nucleotide Resolution in Human Genomic DNA by Ligation-mediated Polymerase Chain Reaction

1995 • 89 citations

Interaction of Copper(I) with Nucleic Acids

1990 • 75 citations

Detection of DNA adducts at the DNA sequence level by ligation-mediated PCR

1993 • 73 citations

Influence of reductants upon optical characteristics of the DNA–Cu²⁺ complex

1967 • 58 citations

Site-specific cleavage of single-stranded DNAs at unique sites by a copper-dependent redox reaction

1988 • 56 citations

Interaction of Copper(II) with Deoxyribonucleic Acid below 30°^*

1967 • 51 citations

[34] Analysis of methylation and chromatin structure

1993 • 36 citations

Ligation-mediated PCR: Applications to genomic footprinting

1991 • 35 citations

Site-specific DNA damage by phenylhydrazine and phenelzine in the presence of copper(II) ion or iron(III) complexes: roles of active oxygen species and carbon radicals

1992 • 32 citations

A Hot Spot for Hydrogen Peroxide-Induced Damage in the Human Hypoxia-Inducible Factor 1 Binding Site of thePGK 1Gene

1997 • 25 citations

Genomic Footprinting by Ligation Mediated Polymerase Chain Reaction

2003 • 23 citations

Apparent sequence preference in cleavage of linear B-DNA by the Cu(II): Thiol system

1989 • 15 citations

Genomic Sequencing

2003 • 7 citations

Polypeptide composition and an immunological analysis of DNA methyltransferases from different species

1989 • 3 citations