Trypanosome trans-splicing utilizes 2′-5′ branches and a corresponding debranching activity.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose

1970 • 1,349 citations

Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication.

1979 • 1,136 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

PRE-mRNA SPLICING

1986 • 673 citations

A trans-spliced leader sequence on actin mRNA in C. elegans

1987 • 639 citations

Detection of Single Base Substitutions by Ribonuclease Cleavage at Mismatches in RNA:DNA Duplexes

1985 • 538 citations

RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis

1986 • 524 citations

Evolutionary diversity of eukaryotic small-subunit rRNA genes.

1986 • 493 citations

Evidence for Trans splicing in trypanosomes

1986 • 486 citations

A self-splicing RNA excises an intron lariat

1986 • 449 citations

[3] Use of in Vitro32P labeling in the sequence analysis of nonradioactive tRNAs

1979 • 442 citations

DISCONTINUOUS TRANSCRIPTION AND ANTIGENIC VARIATION IN TRYPANOSOMES

1986 • 418 citations

Identification of a novel Y branch structure as an intermediate in trypanosome mRNA processing: Evidence for Trans splicing

1986 • 354 citations

Excised group II introns in yeast mitochondria are lariats and can be formed by self-splicing in vitro

1986 • 346 citations

Point mutations identify the conserved, intron-contained TACTAAC box as an essential splicing signal sequence in yeast

1984 • 339 citations

An RNA Processing Activity That Debranches RNA Lariats

1985 • 300 citations

Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors

1985 • 232 citations

Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes

1984 • 193 citations

RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes

1982 • 183 citations

Trypanosome mRNAs have unusual "cap 4" structures acquired by addition of a spliced leader.

1987 • 179 citations

Identification of a small rna containing the trypanosome spliced leader: A donor of shared 5′ sequences of trypanosomatid mRNAs?

1984 • 176 citations

Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro

1985 • 172 citations

Trypanosome mRNAs share a common 5′ spliced leader sequence

1984 • 163 citations

Chromosome rearrangements in trypanosoma brucei

1984 • 161 citations

Tandem repetition of the 5′ mini-exon of variant surface glycoprotein genes: A multiple promoter for VSG gene transcription?

1983 • 152 citations

Comparison of the genes coding for the common 5′ terminal sequence of messenger RNAs in three trypanosome species

1984 • 150 citations

Discontinuous synthesis of mRNA in trypanosomes.

1984 • 145 citations

Sequences homologous to the variant antigen mRNA spliced leader are located in tandem repeats and variable orphons in Trypanosoma brucei

1983 • 143 citations

ANTIGENIC VARIATION IN AFRICAN TRYPANOSOMES

1985 • 121 citations

Many trypanosome messenger RNAs share a common 5′ terminal sequence

1984 • 120 citations

Polyadenylylated nuclear RNA contains branches

1983 • 120 citations

Effect of mutations at the lariat branch acceptor site on β-globin pre-mRNA splicing in vitro

1986 • 111 citations

Conserved Sequences and Transcription of the hsp70 Gene Family in Trypanosoma brucei

1986 • 108 citations

In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei.

1987 • 92 citations

RNA splicing and intron turnover are greatly diminished by a mutant yeast branch point.

1986 • 80 citations

Direct analysis of the mini-exon donor RNA ofTrypanosoma brucei: detection of a novel cap structure also present in messenger RNA

1987 • 73 citations

Sequences homologous to variant antigen mRNA spliced leader in Trypanosomatidae which do not undergo antigenic variation

1984 • 66 citations

The monogenetic kinetoplastid protozoan,Crithidia fasciculate, contains a transcriptionally active, multicopy mini-exon sequence

1987 • 64 citations

Purification of a RNA debranching activity from HeLa cells.

1987 • 63 citations

The use of terminal blocking groups for the specific joining of oligonucleotides in RNA ligase reactions containing equimolar concentrations of acceptor and donor molecules

1976 • 58 citations

[30] Purification of messenger RNA and heterogeneous nuclear RNA containing poly(A) sequences

1974 • 55 citations

Characterization of the 1.35 Kilobase DNA repeat unit containing the conserved 35 nucleotides at the 5′-termini of variable surface glyeoprotein mRNAs InTrypanosoma brucei

1984 • 54 citations

Chemical synthesis of branched RNA

1986 • 53 citations

Gene activation and re-expression of a Trypanosoma brucei variant surface glycoprotein.

1983 • 48 citations

Trypanosome trans-splicing utilizes 2′-5′ branches and a corresponding debranching activity.

1988 • 37 citations

The cap of both miniexon-derived RNA and mRNA of trypanosomes is 7-methylguanosine.

1988 • 28 citations

The Cap of Both Miniexon-Derived RNA and mRNA of Trypanosomes Is 7-Methylguanosine

1988 • 10 citations