Elevated 80K-H protein in breast cancer: A role for FGF-1 stimulation of 80K-H

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Genomic sequencing.

1984 • 8,343 citations

A Human Cell Line From a Pleural Effusion Derived From a Breast Carcinoma 2

1973 • 2,431 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer.

1996 • 1,393 citations

Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells.

2000 • 359 citations

Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins.

1996 • 340 citations

Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-src oncogene product.

1992 • 309 citations

DNA flow cytometry and prognostic factors in 1331 frozen breast cancer specimens

1988 • 301 citations

Phase II study of weekly intravenous trastuzumab (Herceptin) in patients with HER2/neu-overexpressing metastatic breast cancer.

1999 • 300 citations

Involvement of pp60c-src with two major signaling pathways in human breast cancer.

1994 • 273 citations

BEK and FLG, two receptors to members of the FGF family, are amplified in subsets of human breast cancers.

1991 • 238 citations

Human breast carcinoma desmoplasia is PDGF initiated

2000 • 214 citations

Combination therapy with trastuzumab (Herceptin) and cisplatin for chemoresistant metastatic breast cancer: evidence for receptor-enhanced chemosensitivity.

1999 • 182 citations

Prognostic value of steroid hormone receptors: multivariate analysis of systemically untreated patients with node negative primary breast cancer.

1987 • 150 citations

Signal Transduction Pathway of Human Fibroblast Growth Factor Receptor 3

1997 • 139 citations

Purification and characterization of an Mr 87,000 protein kinase C substrate from rat brain.

1987 • 117 citations

Co-expression of epidermal growth factor receptor and transforming growth factor-α predicts worse prognosis in breast-cancer patients

2000 • 93 citations

Prognostic value of estrogen and progesterone receptors in operable breast cancer: Results of a univariate and multivariate analysis

1988 • 91 citations

Expression of the FGFR1 gene in human breast‐carcinoma cells

1994 • 85 citations

Localization of platelet-derived growth factor beta receptor expression in the periepithelial stroma of human breast carcinoma.

1996 • 83 citations

Intact and functional fibroblast growth factor (FGF) receptor-1 trafficks near the nucleus in response to FGF-1.

1994 • 75 citations

Isolation of cDNAs encoding a substrate for protein kinase C: Nucleotide sequence and chromosomal mapping of the gene for a human 80K protein

1989 • 69 citations

Identification of p90, a Prominent Tyrosine-phosphorylated Protein in Fibroblast Growth Factor-stimulated Cells, as 80K-H

1996 • 67 citations

Expression of collagen, interstitial collagenase, and tissue inhibitor of metalloproteinases-1 in restenosis after carotid endarterectomy.

1996 • 66 citations

MCF-7 breast carcinoma cells overexpressing FGF-1 form vascularized, metastatic tumors in ovariectomized or tamoxifen-treated nude mice

1997 • 64 citations

Altered intracellular localization of fibroblast growth factor receptor 3 in human breast cancer

2001 • 58 citations

Overexpression of a secretory form of FGF-1 promotes MMP-1-mediated endothelial cell migration

2000 • 58 citations

Purification of two distinct proteins of approximate Mr 80,000 from human epithelial cells and identification as proper substrates for protein kinase C

1990 • 56 citations

Fibroblast growth factor overexpressing breast carcinoma cells as models of angiogenesis and metastasis

1996 • 46 citations

SUC1-Associated Neurotrophic Factor Target (SNT) Protein Is a Major FGF-Stimulated Tyrosine Phosphorylated 90-kDa Protein Which Binds to the SH2 Domain of GRB2

1996 • 46 citations

Both autocrine and paracrine effects of transfected acidic fibroblast growth factor are involved in the estrogen-independent and antiestrogen-resistant growth of MCF-7 breast cancer cells.

1998 • 45 citations

Molecular Significance of Excess Body Weight in Postmenopausal Breast Cancer Patients, in Relation to Expression of Insulin‐like Growth Factor I Receptor and Insulin‐like Growth Factor II Genes

2001 • 42 citations

Immunohistochemical study of TGF-alpha, TGF-beta1, EGFR, and IGF-1 expression in human breast carcinoma.

1997 • 40 citations

A Protein Modulator Stimulates C Kinase‐Dependent Phosphorylation of a 90K Substrate in Synaptic Membranes

1986 • 40 citations

Interaction of transforming growth factor-alpha and epidermal growth factor receptor in breast carcinoma. An immunohistologic study

1994 • 35 citations

A new, rapid colorimetric assay for quantitative determination of cellular proliferation, growth inhibition, and viability

1993 • 27 citations

Expression of acidic fibroblast growth factor (aFGF) and fibroblast growth factor receptor 4 (FGFR4) in breast fibroadenomas

2001 • 26 citations

Immunohistochemistry on Histological Sections from Small (50 mg) Samples of Pulverized Breast Cancer

1993 • 16 citations

Aberrant FGF-2, FGF-3, FGF-4 and C-ERB-B2 Gene Copy Number in Human Ovarian, Breast and Endometrial Tumours

1996 • 13 citations