Lysophosphatidylcholine and lyso-PAF display PAF-like activity derived from contaminating phospholipids

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid

1960 • 2,598 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

Low Density Lipoprotein Oxidation and Its Pathobiological Significance

1997 • 1,642 citations

The role of oxidized lipoproteins in atherogenesis

1996 • 1,382 citations

Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins

1990 • 871 citations

Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells.

1992 • 828 citations

Platelet-Activating Factor and Related Lipid Mediators

2000 • 749 citations

Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis.

1988 • 655 citations

Anti-inflammatory properties of a platelet-activating factor acetylhydrolase

1995 • 529 citations

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1‐phosphate

1998 • 516 citations

Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein.

1995 • 412 citations

Human plasma platelet-activating factor acetylhydrolase. Association with lipoprotein particles and role in the degradation of platelet-activating factor.

1987 • 404 citations

Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro.

1985 • 380 citations

Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells.

1994 • 332 citations

Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells.

1995 • 311 citations

Human plasma platelet-activating factor acetylhydrolase. Oxidatively fragmented phospholipids as substrates

1991 • 308 citations

Oxidized Alkyl Phospholipids Are Specific, High Affinity Peroxisome Proliferator-activated Receptor γ Ligands and Agonists

2001 • 262 citations

An Oxidized Derivative of Phosphatidylcholine is a Substrate for the Platelet-Activating Factor Acetylhydrolase from Human Plasma

1989 • 234 citations

Oxidatively fragmented phosphatidylcholines activate human neutrophils through the receptor for platelet-activating factor

1991 • 221 citations

Hydrolysis of phosphatidylcholine during LDL oxidation is mediated by platelet-activating factor acetylhydrolase.

1989 • 220 citations

Lysophosphatidylcholine: Essential role in the inhibition of endothelium-dependent vasorelaxation by oxidized low density lipoprotein

1990 • 187 citations

Inflammatory Platelet-activating Factor-like Phospholipids in Oxidized Low Density Lipoproteins Are Fragmented Alkyl Phosphatidylcholines

1999 • 186 citations

Lysophosphatidylcholine (LPC) induces proinflammatory cytokines by a platelet-activating factor (PAF) receptor-dependent mechanism

1999 • 177 citations

Purification, Properties, Sequencing, and Cloning of a Lipoprotein-Associated, Serine-Dependent Phospholipase Involved in the Oxidative Modification of Low-Density Lipoproteins

1996 • 163 citations

Induction of Macrophage VEGF in Response to Oxidized LDL and VEGF Accumulation in Human Atherosclerotic Lesions

1998 • 151 citations

Effects of lysolipids and oxidatively modified low density lipoprotein on endothelium-dependent relaxation of rabbit aorta.

1993 • 145 citations

Oxidized Low Density Lipoprotein and Lysophosphatidylcholine Stimulate Cell Cycle Entry in Vascular Smooth Muscle Cells

1996 • 142 citations

Platelet-activating factor and related lipid mediators

1988 • 130 citations

Induction by Lysophosphatidylcholine, a Major Phospholipid Component of Atherogenic Lipoproteins, of Human Coronary Artery Smooth Muscle Cell Migration

1998 • 128 citations

Lysophosphatidylcholine induces the production of IL-1β by human monocytes

1998 • 125 citations

Platelet-activating factor receptor and signal transduction

1992 • 98 citations

Reduced Na+ -K+ -ATPase Activity and Plasma Lysophosphatidylcholine Concentrations in Diabetic Patients

1994 • 94 citations

Regulation of cell growth by oxidized LDL

2000 • 93 citations

Oxidative modification of low density lipoprotein in normal and hyperlipidemic patients: effect of lysophosphatidylcholine composition on vascular relaxation

1997 • 92 citations

Lysophosphatidylcholine stimulates the expression and production of MCP-1 by human vascular endothelial cells

1996 • 87 citations

Substrate specificity of plasma lysolecithin acyltransferase and the molecular species of lecithin formed by the reaction.

1985 • 64 citations

Characterization of the alkyl ether species of phosphatidylcholine in bovine heart

1977 • 58 citations

Lysophosphatidylcholine stimulates phospholipase D activity in mouse peritoneal macrophages

1999 • 56 citations

Lysophosphatidylcholine transduces Ca2+ signaling via the platelet-activating factor receptor in macrophages

1997 • 50 citations

Lipid peroxidation in low density lipoproteins from human plasma and egg yolk promotes accumulation of 1‐acyl analogues of platelet‐activating factor‐like lipids

1996 • 49 citations

Stereospecific chemoattraction of lymphoblastic cells by gradients of lysophosphatidylcholine.

1982 • 44 citations

Intracutaneous Injection of Lysophosphatidylcholine Induces Skin Inflammation and Accumulation of Leukocytes

2000 • 42 citations

The vascular distribution of the platelet-activating factor receptor.

1996 • 42 citations

Regulation of PAF-acether (platelet-activating factor) biosynthesis in cultured human vascular endothelial cells stimulated with thrombin

1987 • 42 citations

Platelet-activating factor and analogues: comparative studies with human neutrophils and rabbit platelets.

1983 • 39 citations

Identification and functional characterization of platelet-activating factor receptors in human leukocyte populations using polyclonal anti-peptide antibody.

1993 • 38 citations

Identification of short-chain oxidized phosphatidylcholine in human plasma

1996 • 37 citations

Copper-Catalyzed Oxidation Mediates PAF Formation in Human LDL Subspecies

1997 • 36 citations

Induction of high‐affinity paf receptor expression during T cell activation

1992 • 32 citations

IFN-gamma up-regulates platelet-activating factor receptor gene expression in human monocytes.

1994 • 31 citations

Stimulation of monocytes and platelets by short-chain phosphatidylcholines with and without terminal carboxyl group

1998 • 31 citations

A radioreceptor binding assay for platelet-activating factor (PAF) using membranes from CHO cells expressing human PAF receptor

1995 • 27 citations

The Chemical and Biological Properties of PAF Agonists, Antagonists, and Biosynthetic Inhibitors

1987 • 20 citations

Induction of functionally active platelet-activating factor receptors in rat alveolar macrophages.

1993 • 18 citations

Mechanism of Endothelium-Dependent Vasorelaxation Evoked by Lysophosphatidylcholine.

1998 • 9 citations

Long‐lasting inhibitory activity of the hetrazepinic BN 50730 on exudation and cellular alterations evoked by PAF and LPS

1994 • 7 citations

Effect of inhaled lyso-platelet-activating factor on airway microvascular leakage in the guinea pig

1993 • 7 citations

Lysophosphatidylcholine Induces Heparin‐Binding Epidermal Growth Factor‐like Growth Factor and Interferon‐γ in Human T‐Lymphocytes

1997 • 6 citations