Analysis of expression and function of the costimulatory molecule 4-1BB in alloimmune responses.

CD28/B7 SYSTEM OF T CELL COSTIMULATION

1996 • 2,726 citations

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

1993 • 1,753 citations

Determination of lymphocyte division by flow cytometry

1994 • 1,712 citations

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1998 • 1,546 citations

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1996 • 1,457 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Differential T Cell Costimulatory Requirements in CD28-Deficient Mice

1993 • 1,271 citations

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

1997 • 886 citations

4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses

1997 • 777 citations

IMMUNE REGULATION BY CD40 AND ITS LIGAND GP39

1996 • 653 citations

Ox-40 Ligand: A Potent Costimulatory Molecule for Sustaining Primary CD4 T Cell Responses

1998 • 515 citations

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

1988 • 505 citations

Acquisition of immunologic self-tolerance

1989 • 484 citations

Inducible T cell antigen 4-1BB. Analysis of expression and function.

1993 • 416 citations

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

1995 • 398 citations

Cutting Edge: 4-1BB Is a Bona Fide CD8 T Cell Survival Signal

1999 • 379 citations

Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.

1994 • 379 citations

Asialo GM1+ CD8+ T cells play a critical role in costimulation blockade–resistant allograft rejection

1999 • 351 citations

4-1BB and Ox40 Are Members of a Tumor Necrosis Factor (TNF)-Nerve Growth Factor Receptor Subfamily That Bind TNF Receptor-Associated Factors and Activate Nuclear Factor κB

1998 • 342 citations

Costimulation of CD28- T lymphocytes by 4-1BB ligand.

1997 • 333 citations

CD40-gp39 INTERACTIONS PLAY A CRITICAL ROLE DURING ALLOGRAFT REJECTION

1996 • 331 citations

Molecular cloning of a ligand for the inducible T cell gene 4‐1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor

1993 • 328 citations

CD28-independent, TRAF2-dependent Costimulation of Resting T Cells by 4-1BB Ligand

1998 • 321 citations

Functional expression of the costimulatory molecule, B7/BB1, on murine dendritic cell populations.

1992 • 306 citations

The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response.

1996 • 284 citations

Analysis of 4-1BB Ligand (4-1BBL)-Deficient Mice and of Mice Lacking Both 4-1BBL and CD28 Reveals a Role for 4-1BBL in Skin Allograft Rejection and in the Cytotoxic T Cell Response to Influenza Virus

1999 • 280 citations

4-1BB Ligand, a Member of the TNF Family, Is Important for the Generation of Antiviral CD8 T Cell Responses

1999 • 259 citations

Moslecular and biological characterization of human 4‐1BB and its ligands

1994 • 242 citations

4‐1BB T‐cell antigen binds to mature B cells and macrophages, and costimulates anti‐μ‐primed splenic B cells

1994 • 223 citations

Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway

1998 • 218 citations

CD28-Independent Costimulation of T Cells by OX40 Ligand and CD70 on Activated B Cells

1999 • 180 citations

Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP.

1995 • 178 citations

CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection

1996 • 154 citations

OX-40: life beyond the effector T cell stage

1998 • 152 citations

4-1BBL Cooperates with B7-1 and B7-2 in Converting a B Cell Lymphoma Cell Line into a Long-Lasting Antitumor Vaccine

1999 • 130 citations

Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells

1999 • 122 citations

Fatal interactions: fas-induced apoptosis of mature T cells

1994 • 118 citations

CD30 Overexpression Enhances Negative Selection in the Thymus and Mediates Programmed Cell Death Via a Bcl-2-Sensitive Pathway

1999 • 109 citations

Involvement of the Protein Tyrosine Kinase p56lck in T Cell Signaling and Thymocyte Development

1994 • 75 citations

Novel T cell antigen 4-1BB associates with the protein tyrosine kinase p56lck1.

1993 • 62 citations

T-cell activation molecule 4-1BB binds to extracellular matrix proteins.

1992 • 57 citations

Pathways leading to cell death in T cells

1997 • 53 citations