Developmental territories created by mutual antagonism between Wingless and Decapentaplegic

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 1,546 citations

Pattern Regulation in Epimorphic Fields

1976 • 871 citations

Organizing activity of wingless protein in Drosophila

1993 • 852 citations

Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

1994 • 842 citations

TGFβ Signaling: Receptors, Transducers, and Mad Proteins

1996 • 840 citations

Developmental Compartmentalisation of the Wing Disk of Drosophila

1973 • 770 citations

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

1987 • 756 citations

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

1994 • 624 citations

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog

1992 • 585 citations

Genetic Control of Wing Disc Development in Drosophila

1975 • 584 citations

Morphogens, Compartments, and Pattern: Lessons from Drosophila?

1996 • 559 citations

Lakes Beneath the Antarctic Ice Sheet

1973 • 555 citations

Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing

1995 • 489 citations

The engrailed locus of drosophila: In situ localization of transcripts reveals compartment-specific expression

1985 • 456 citations

The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal.

1994 • 407 citations

The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation.

1992 • 400 citations

Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila

1993 • 359 citations

Distal Regeneration and Symmetry

1981 • 352 citations

Developmental compartmentalization in the dorsal mesothoracic disc of Drosophila

1976 • 343 citations

dishevelled is required during wingless signaling to establish both cell polarity and cell identity

1994 • 335 citations

Sending and Receiving the Hedgehog Signal: Control by the Drosophila Gli Protein Cubitus interruptus

1996 • 320 citations

Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila

1994 • 317 citations

Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development

1995 • 315 citations

An absolute requirement for both the type II and type I receptors, punt and thick veins, for Dpp signaling in vivo

1995 • 312 citations

Protein kinase A and hedgehog signaling in drosophila limb development

1995 • 310 citations

Pattern formation in a secondary field: a hierarchy of regulatory genes subdivides the developing Drosophila wing disc into discrete subregions

1993 • 292 citations

Clonal analysis of primordial disc cells in the early embryo of Drosophila melanogaster

1976 • 276 citations

Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family

1995 • 275 citations

Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic

1994 • 275 citations

Establishment of compartments in the developing leg imaginal discs ofDrosophila melanogaster

1976 • 271 citations

Cell determination boundaries as organizing regions for secondary embryonic fields

1983 • 267 citations

A wingless -Dependent Polar Coordinate System in Drosophila Imaginal Discs

1993 • 266 citations

Organization of wing formation and induction of a wing-patterning gene at the dorsal/ventral compartment boundary

1994 • 254 citations

Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor

1994 • 254 citations

Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3' cis-regulatory elements.

1990 • 250 citations

Allocation of the thoracic imaginal primordia in the Drosophila embryo

1993 • 248 citations

Origin and evolution of insect wings and their relation to metamorphosis, as documented by the fossil record

1978 • 245 citations

Genetic analysis of pattern formation in the Arabidopsis embryo

1991 • 244 citations

Regeneration, duplication and transdetermination in fragments of the leg disc of Drosophila melanogaster

1971 • 239 citations

wingless inhibits morphogenetic furrow movement in the Drosophila eye disc

1995 • 229 citations

Embryonic and imaginal requirements for wingless, a segment-polarity gene in Drosophila

1988 • 228 citations

Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse.

1995 • 225 citations

Mad acts downstream of Dpp receptors, revealing a differential requirement for dpp signaling in initiation and propagation of morphogenesis in the Drosophila eye

1996 • 223 citations

The causal analysis of development in the past half century: a personal history

1992 • 214 citations

Multiple functions of segment polarity genes in Drosophila

1987 • 212 citations

The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development.

1994 • 212 citations

Transcription of the segment-polarity gene wingless in the imaginal discs of Drosophila, and the phenotype of a pupal-lethal wg mutation

1988 • 211 citations

wingless and patched are negative regulators of the morphogenetic furrow and can affect tissue polarity in the developing Drosophila compound eye

1995 • 210 citations

Repression of ci-D in posterior compartments of Drosophila by engrailed.

1990 • 205 citations

Cell lineage relationships in the imaginal wing disc of Drosophila melanogaster

1970 • 203 citations

Specificity of bone morphogenetic protein-related factors: cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60A.

1994 • 195 citations

patched overexpression alters wing disc size and pattern: transcriptional and post-transcriptional effects on hedgehog targets

1995 • 185 citations

Synergistic principles of development: overlapping patterning systems in Xenopus mesoderm induction

1992 • 178 citations

The role of apterous in the control of dorsoventral compartmentalization and PS integrin gene expression in the developing wing of Drosophila

1994 • 176 citations

Compartments and appendage development in Drosophila

1995 • 175 citations

Dual functions of wingless in the Drosophila leg imaginal disc

1995 • 167 citations

The early development of mesothoracic compartments in Drosophila

1977 • 166 citations

The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs

1990 • 144 citations

Drawing a stripe in Drosophila imaginal disks: negative regulation of decapentaplegic and patched expression by engrailed.

1995 • 134 citations

Further studies of the engrailed phenotype in Drosophila.

1982 • 130 citations

Ectopic decapentaplegic in the Drosophila midgut alters the expression of five homeotic genes, dpp, and wingless, causing specific morphological defects

1994 • 117 citations

Pattern formation in the visual centers of the Drosophila brain: wingless acts via decapentaplegic to specify the dorsoventral axis

1994 • 111 citations

Decapentaplegic restricts the domain of wingless during Drosophila limb patterning

1996 • 104 citations

Cell lineage and development in the larval epidermis ofDrosophila melanogaster

1979 • 100 citations

Mechanisms of compartment formation: Evidence that non-proliferating cells do not play a critical role in defining the D/V lineage restriction in the developing wing of Drosophila

1993 • 80 citations

decapentaplegic, a target gene of the wingless signalling pathway in the Drosophila midgut

1996 • 68 citations

A blastoderm fate map of compartments and segments of the Drosophila head

1981 • 63 citations

The origin, patterning and evolution of insect appendages

1993 • 58 citations

Functional Conservation of the Wnt Signaling Pathway Revealed by Ectopic Expression of Drosophila dishevelled in Xenopus

1995 • 58 citations

Embryonic expression patterns of the drosophila decapentaplegic gene: Separate regulatory elements control blastoderm expression and lateral ectodermal expression

1994 • 43 citations

Prolegs, Legs and Wings of Insects

1984 • 20 citations

A no-wing situation

1993 • 7 citations

Prolegs, legs and wings of insects

1994 • 4 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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