Thyroid Regulation of NADPH:Cytochrome P450 Oxidoreductase: Identification of a Thyroid-Responsive Element in the 5′-Flank of the Oxidoreductase Gene

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

1996 • 2,895 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

Thyroid Hormone Receptors: Multiple Forms, Multiple Possibilities*

1993 • 1,009 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Differential Recognition of Target Genes by Nuclear Receptor Monomers, Dimers, and Heterodimers*

1994 • 789 citations

Depletion of L-3,5,3'-Triiodothyronine and L-Thyroxine in Euthyroid Calf Serum for Use in Cell Culture Studies of the Action of Thyroid Hormone*

1979 • 653 citations

The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors

1991 • 603 citations

Modular structure of a chicken lysozyme silencer: Involvement of an unusual thyroid hormone receptor binding site

1990 • 487 citations

RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors.

1992 • 446 citations

NADPH-cytochrome P-450 oxidoreductase: flavin mononucleotide and flavin adenine dinucleotide domains evolved from different flavoproteins

1986 • 241 citations

Transcriptional regulation of rat liver epoxide hydratase, NADPH-Cytochrome P-450 oxidoreductase, and cytochrome P-450b genes by phenobarbital.

1983 • 222 citations

Identification of Nuclear Factors that Enhance Binding of the Thyroid Hormone Receptor to a Thyroid Hormone Response Element

1989 • 219 citations

Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers.

1992 • 216 citations

Molecular basis of thyroid hormone regulation of myelin basic protein gene expression in rodent brain.

1991 • 209 citations

A nuclear factor that enhances binding of thyroid hormone receptors to thyroid hormone response elements.

1990 • 192 citations

Regulation of gene expression by the thyroid hormone receptor

1990 • 166 citations

Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor.

1991 • 163 citations

Induction of the hepatic mixed-function oxidase system by synthetic glucocorticoids. Transcriptional and post-transcriptional regulation.

1987 • 128 citations

Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes.

1985 • 123 citations

In contrast to the glucocorticoid receptor, the thyroid hormone receptor is translated in the DNA binding state and is not associated with hsp90.

1990 • 112 citations

Stabilization of a Specific Nuclear mRNA Precursor by Thyroid Hormone

1985 • 96 citations

Human NADPH-P450 oxidoreductase: complementary DNA cloning, sequence and vaccinia virus-mediated expression and localization of the CYPOR gene to chromosome 7.

1989 • 87 citations

Transcriptional activation and stabilization of malic enzyme mRNA precursor by thyroid hormone.

1988 • 84 citations

NADPH-cytochrome P-450 oxidoreductase gene organization correlates with structural domains of the protein

1990 • 83 citations

Thyroid hormone stimulation of NADPH P450 reductase expression in liver and extrahepatic tissues. Regulation by multiple mechanisms.

1992 • 79 citations

Capacity for cooperative binding of thyroid hormone (T3) receptor dimers defines wild type T3 response elements.

1992 • 79 citations

Hypophysectomy differentially alters P-450 protein levels and enzyme activities in rat liver: pituitary control of hepatic NADPH cytochrome P-450 reductase.

1989 • 75 citations

Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif.

1996 • 74 citations

Characterization and tissue expression of multiple triiodothyronine receptor-auxiliary proteins and their relationship to the retinoid X-receptors.

1993 • 69 citations

Rapid induction of rat liver S14 gene transcription by thyroid hormone

1989 • 65 citations

Oligomeric binding of T3 receptor is required for maximal T3 response.

1991 • 63 citations

Positive and negative regulation of retinoid X receptor gene expression by thyroid hormone in the rat. Transcriptional and post-transcriptional controls by thyroid hormone.

1994 • 53 citations

Retinoid-X receptor (RXR) differentially augments thyroid hormone response in cell lines as a function of the response element and endogenous RXR content.

1995 • 43 citations

Transcriptional activation of the rat liver S14 gene during postnatal development.

1988 • 38 citations

The Interplay of Half-site Sequence and Spacing on the Activity of Direct Repeat Thyroid Hormone Response Elements

1995 • 29 citations

NADPH Cytochrome P-450 Oxidoreductase Gene: Identification and Characterization of the Promoter Region

1994 • 27 citations

Directed Mutagenesis Using the Polymerase Chain Reaction

1998 • 24 citations

Protein and Gene Structure and Regulation of NADPH-Cytochrome P450 Oxidoreductase

1993 • 23 citations

Post-transcriptional regulation of rat alpha cardiac myosin heavy chain gene expression.

1994 • 23 citations

Transcriptional Regulation of the TATA-less NADPH Cytochrome P-450 Oxidoreductase Gene

1996 • 18 citations

Glucocorticoid repression and basal regulation of the epoxide hydrolase promoter

1990 • 17 citations

[27] Quantitation of related gene products by nuclear run-on and northern blot analysis

1991 • 13 citations