Receptor phosphorylation does not mediate cross talk between muscarinic M₃and bradykinin B₂receptors

Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A

1997 • 1,247 citations

Turning off the signal: desensitization of β‐adrenergic receptor function

1990 • 1,241 citations

Molecular mechanisms of membrane receptor desensitization

1993 • 442 citations

G protein—coupled receptor kinases

1993 • 434 citations

G protein-coupled receptors: heterologous regulation of homologous desensitization and its implications

1996 • 234 citations

Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells.

1987 • 206 citations

Guanosine 5'-O-(thiotriphosphate)-dependent inositol trisphosphate formation in membranes is inhibited by phorbol ester and protein kinase C.

1987 • 203 citations

Differential Regulation of Muscarinic Acetylcholine Receptor-sensitive Polyphosphoinositide Pools and Consequences for Signaling in Human Neuroblastoma Cells

1998 • 172 citations

Development of an antiserum against m3 muscarinic receptors: distribution of m3 receptors in rat tissues and clonal cell lines.

1991 • 159 citations

Differences in phosphorylation of formylpeptide and C5a chemoattractant receptors correlate with differences in desensitization.

1993 • 154 citations

Heterogeneity of [3H]inositol 1,4,5-trisphosphate binding sites in adrenal-cortical membranes. Characterization and validation of a radioreceptor assay

1990 • 150 citations

Regulation of stably transfected platelet activating factor receptor in RBL-2H3 cells. Role of multiple G proteins and receptor phosphorylation.

1994 • 141 citations

Regulation of Adrenergic Receptor Function by Phosphorylation

1986 • 135 citations

Ligand-induced Phosphorylation/Dephosphorylation of the Endogenous Bradykinin B2 Receptor from Human Fibroblasts

1996 • 128 citations

Regulation of G Protein-Coupled Receptors by Receptor Kinases and Arrestins

1995 • 128 citations

Rapid agonist-mediated phosphorylation of m3-muscarinic receptors revealed by immunoprecipitation

1993 • 110 citations

Muscarinic Receptor‐Mediated Inositol 1,4,5‐Trisphosphate Formation in SH‐SY5Y Neuroblastoma Cells Is Regulated Acutely by Cytosolic Ca²⁺ and by Rapid Desensitization

1994 • 88 citations

C-terminal Truncation of the Neurokinin-2 Receptor Causes Enhanced and Sustained Agonist-induced Signaling

1995 • 76 citations

Stimulus-dependent Phosphorylation of G-protein-coupled Receptors by Casein Kinase 1α

1997 • 75 citations

Phosphorylation of the Prostacyclin Receptor during Homologous Desensitization

1998 • 70 citations

Rapid desensitization of muscarinic m3 receptor-stimulated polyphosphoinositide responses.

1992 • 68 citations

Activation of Endothelin ETA Receptors Induces Phosphorylation of α1b-Adrenoreceptors in Rat-1 Fibroblasts

1997 • 68 citations

Structural features of the human bradykinin B2 receptor probed by agonists, antagonists, and anti-idiotypic antibodies

1993 • 67 citations

Delineation of a region in the B2 bradykinin receptor that is essential for high-affinity agonist binding.

1994 • 61 citations

Rapid agonist mediated phosphorylation of the metabotropic glutamate receptor 1α by protein kinase C in permanently transfected BHK cells

1995 • 57 citations

Quantitative comparisons of muscarinic and bradykinin receptor‐mediated Ins (1,4,5)P₃ accumulation and Ca²⁺ signalling in human neuroblastoma cells

1995 • 56 citations

Phosphorylation of phospholipase C-coupled receptors

1997 • 54 citations

Multiple phosphorylation sites are required for pathway-selective uncoupling of the 5-hydroxytryptamine1A receptor by protein kinase C.

1995 • 51 citations

Differential coupling of m1, m2 and m3 muscarinic receptor subtypes to inositol 1,4,5-trisphosphate and adenosine 3',5'-cyclic monophosphate accumulation in Chinese hamster ovary cells.

1995 • 49 citations

Phosphorylation and Functional Desensitization of the α_2A-Adrenergic Receptor by Protein Kinase C

1998 • 48 citations

Evidence of an important and direct role for protein kinase C in agonist‐induced phosphorylation leading to desensitization of the angiotensin AT_1A receptor

1997 • 44 citations

Disruption by lithium of phosphatidylinositol-4,5-bisphosphate supply and inositol-1,4,5-trisphosphate generation in Chinese hamster ovary cells expressing human recombinant m1 muscarinic receptors.

1994 • 40 citations

Different modes of regulation for receptors activating phospholipase C in the rat pancreatoma cell line AR4-2J.

1991 • 36 citations

Crosstalk: phosphorylation of α_1b‐adrenoceptors induced through activation of bradykinin B2 receptors

1998 • 32 citations

Heterologous desensitization of both phosphoinositide and Ca2+ signaling in SH-SY5Y neuroblastoma cells: a role for intracellular Ca2+ store depletion?

1995 • 29 citations

Contrasting effects of phorbol ester and agonist-mediated activation of protein kinase C on phosphoinositide and Ca2+ signalling in a human neuroblastoma

1996 • 28 citations

A rapid attenuation of muscarinic agonist stimulated phosphoinositide hydrolysis precedes receptor sequestration in human SH-SY-5Y neuroblastoma cells

1994 • 23 citations

Protein kinase C mediates delayed inhibitory feedback regulation of human neurokinin type 1 receptor activation of phospholipase C in UC11 astrocytoma cells.

1994 • 20 citations

Acute regulation of the receptor-mediated phosphoinositide signal transduction pathway

1996 • 13 citations

Activation of endothelin eta receptors induces phosphorylation of α1b-adrenoceptors in rat-1 fibroblasts

1997 • 6 citations