The U1 RNA-Binding Site of the U1 Small Nuclear Ribonucleoprotein (snRNP)-Associated A Protein Suggests a Similarity with U2 snRNPs

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information

1981 • 3,596 citations

Are snRNPs involved in splicing?

1980 • 1,206 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation

1986 • 755 citations

The detection of DNA-binding proteins by protein blotting

1980 • 731 citations

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

1989 • 601 citations

The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro

1983 • 593 citations

U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing

1985 • 568 citations

A mechanism for RNA splicing.

1980 • 553 citations

Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus

2001 • 551 citations

SPLICEOSOMAL snRNAs

1988 • 463 citations

mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence.

1986 • 455 citations

Characteristics of a Soluble Nuclear Antigen Precipitating with Sera of Patients with Systemic Lupus Erythematosus

1966 • 452 citations

The 5′ terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors

1984 • 404 citations

Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation

1988 • 401 citations

Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding

1986 • 386 citations

Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein

1983 • 333 citations

Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins

1985 • 307 citations

A protein associated with small nuclear ribonucleoprotein particles recognizes the 3′ splice site of premessenger RNA

1986 • 283 citations

A protein that specifically recognizes the 3′ splice site of mammalian pre-mRNA introns is associated with a small nuclear ribonucleoprotein

1986 • 274 citations

U2 RNA shares a structural domain with U1, U4, and U5 RNAs.

1982 • 236 citations

Primary structure of human nuclear ribonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-rRNA-binding proteins.

1987 • 229 citations

Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome.

1986 • 215 citations

cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins.

1987 • 203 citations

Structural organization of ribonucleoproteins containing small nuclear RNAs from HeLa cells

1982 • 184 citations

Phenylalanines that are conserved among several RNA-binding proteins form part of a nucleic acid-binding pocket in the A1 heterogeneous nuclear ribonucleoprotein.

1988 • 180 citations

Autoantibodies to the U2 small nuclear ribonucleoprotein in a patient with scleroderma-polymyositis overlap syndrome.

1984 • 178 citations

In vitro assembly of U1 snRNPs.

1987 • 145 citations

Analysis of a cDNA clone expressing a human autoimmune antigen: full-length sequence of the U2 small nuclear RNA-associated B" antigen.

1987 • 108 citations

Nucleotide sequence homology at the 3' termini of RNA from vesicular stomatitis virus and its defective interfering particles.

1978 • 97 citations

The conformation of chicken, rat and human U1A RNAs in solution

1981 • 92 citations

Immunization of mice with purified U1 small nuclear ribonucleoprotein (RNP) induces a pattern of antibody specificities characteristic of the anti-Sm and anti-RNP autoimmune response of patients with lupus erythematosus, as measured by monoclonal antibodies.

1986 • 87 citations

Monospecific antibodies reveal details of U2 snRNP structure and interaction between U1 and U2 snRNPs.

1986 • 76 citations

The Mr 70,000 protein of the U1 small nuclear ribonucleoprotein particle binds to the 5' stem-loop of U1 RNA and interacts with Sm domain proteins.

1988 • 75 citations

Reconstitution of the U1 small nuclear ribonucleoprotein particle.

1987 • 72 citations

A sequence-specific conformational epitope on U1 RNA is recognized by a unique autoantibody.

1988 • 67 citations

Terminal sequences of vesicular stomatitis virus RNA are both complementary and conserved

1979 • 62 citations

Autoantibodies specific for U1 RNA and initiator methionine tRNA.

1986 • 57 citations

Loop I of U1 Small Nuclear RNA Is The Only Essential RNA Sequence for Binding of Specific U1 Small Nuclear Ribonucleoprotein Particle Proteins

1988 • 54 citations

U2 small nuclear RNA is remarkably conserved between Schizosaccharomyces pombe and mammals.

1988 • 37 citations

Differential nuclease sensitivity identifies tight contacts between yeast pre-mRNA and spliceosomes.

1986 • 24 citations