Immunization against a dominant tumor antigen abrogates immunogenicity of the tumor.

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

T cell receptor antagonist peptides induce positive selection

1994 • 2,818 citations

Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

1989 • 1,512 citations

Tumor Antigens Recognized by T Lymphocytes

1994 • 1,238 citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

Dominance and Crypticity of T Cell Antigenic Determinants

1993 • 838 citations

Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells

1997 • 719 citations

Induction of antigen-specific T cell anergy: An early event in the course of tumor progression

1998 • 710 citations

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

1982 • 640 citations

Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinial relevance

1995 • 478 citations

Immune surveillance against a solid tumor fails because of immunological ignorance

1999 • 463 citations

Exact prediction of a natural T cell epitope

1991 • 455 citations

Induction of antitumor immunity using bone marrow-generated dendritic cells.

1996 • 323 citations

Apoptotic Death of CD8+ T Lymphocytes After Immunization: Induction of a Suppressive Population of Mac-1+/Gr-1+ Cells

1998 • 321 citations

Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy

1997 • 316 citations

Role of self-peptides in positively selecting the T-cell repertoire

1990 • 300 citations

A Single Major Pathway of T‐Lymphocyte Interactions in Antigen‐Specific Immune Suppression

1981 • 281 citations

Emergence of Idiotype Variants during Treatment of B-Cell Lymphoma with Anti-Idiotype Antibodies

1985 • 257 citations

Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL.

1997 • 256 citations

Reversal of tumor-induced immunosuppression: a new approach to cancer therapy.

1997 • 219 citations

Immunophenotyping of melanomas for tyrosinase: implications for vaccine development.

1995 • 177 citations

Cytotoxic T lymphocytes raised against a subdominant epitope offered as a synthetic peptide eradicate human papillomavirus type 16‐induced tumors

1995 • 168 citations

Identification of Db- and Kb-Restricted Subdominant Cytotoxic T-Cell Responses in Lymphocytic Choriomeningitis Virus-Infected Mice

1998 • 164 citations

Control of Syngeneic Tumor Growth by Activation of CD8+ T Cells: Efficacy Is Limited by Migration Away from the Site and Induction of Nonresponsiveness

1999 • 146 citations

Mechanisms of syngeneic tumor rejection. Susceptibility of host-selected progressor variants to various immunological effector cells.

1982 • 135 citations

Analysis of Expression of the Melanoma-Associated Antigens MART-1 and gp lOO in Metastatic Melanoma Cell Lines and in In Situ Lesions

1996 • 131 citations

Immunodominance analysis of CTL responses to influenza PR8 virus reveals two new dominant and subdominant Kb-restricted epitopes.

1996 • 128 citations

Generation of mucosal cytotoxic T cells against soluble protein by tissue-specific environmental and costimulatory signals

1998 • 122 citations

Primary in vivo responses to ovalbumin. Probing the predictive value of the Kb binding motif.

1993 • 107 citations

Soluble Antigen and CD40 Triggering Are Sufficient to Induce Primary and Memory Cytotoxic T Cells

2000 • 104 citations

Activation and migration of CD8 T cells in the intestinal mucosa.

1997 • 102 citations

B7-CD28 costimulation unveils the hierarchy of tumor epitopes recognized by major histocompatibility complex class I-restricted CD8+ cytolytic T lymphocytes.

1996 • 100 citations

Hierarchy among multiple H-2b-restricted cytotoxic T-lymphocyte epitopes within simian virus 40 T antigen

1995 • 87 citations

MHC class I-restricted epitope spreading in the context of tumor rejection following vaccination with a single immunodominant CTL epitope

1999 • 86 citations

Insertion Signal Sequence Fused to Minimal Peptides Elicits Specific CD8+ T-Cell Responses and Prolongs Survival of Thymoma-bearing Mice

1994 • 83 citations

Prolonged survival of thymoma-bearing mice after vaccination with a soluble protein antigen entrapped in liposomes: a model study.

1992 • 78 citations

Cancer-testis antigens: targets for cancer immunotherapy.

1999 • 76 citations

Biology of simian virus 40 (SV40) transplantation antigen (TrAg)

1977 • 74 citations

Cytotoxic T-Cell Response and In Vivo Protection Against Tumor Cells Harboring Activated ras Proto-oncogenes

1993 • 66 citations

Antigen expressed on tumor cells fails to elicit an immune response, even in the presence of increased numbers of tumor-specific cytotoxic T lymphocyte precursors.

1998 • 64 citations

Do human cancers express sharedprotectiveantigens? or The necessity of remembrance of things past

1996 • 61 citations

Relationship Among Immunodominance of Single CD8+ T Cell Epitopes, Virus Load, and Kinetics of Primary Antiviral CTL Response

1998 • 55 citations

Development of tumor cell resistance to syngeneic cell-mediated cytotoxicity during growth of ascitic mastocytoma P815Y.

1977 • 54 citations

Sensitization of MHC class I-restricted T cells to exogenous proteins: evidence for an alternative class I-restricted antigen presentation pathway.

1995 • 43 citations

Role of a Subdominant H-2Kd-Restricted SV40 Tumor Antigen Cytotoxic T Lymphocyte Epitope in Tumor Rejection

1998 • 29 citations

A first or dominant immunization. I. Suppression of simultaneous cytolytic T cell responses to unrelated alloantigens.

1993 • 28 citations

Harnessing self-reactivity in cancer immunotherapy

1996 • 23 citations

Biology of simian virus 40 (SV40) transplantation antigen (TrAg) X. Tumorigenic potential of mouse cells transformed by SV40 in high responder C57BL/6 mice and correlation with the persistence of SV40 TrAg, early proteins and viral sequences

1983 • 21 citations

Augmentation of antitumor immunity by genetically engineered fibroblast cells to express both B7.1 and interleukin-7

2000 • 17 citations