A C-terminal domain in FosB, absent in FosB/SF and Fra-1, which is able to interact with the TATA binding protein, is required for altered cell growth.

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

Crystal structure of a yeast TBP/TATA-box complex

1993 • 1,082 citations

Co-crystal structure of TBP recognizing the minor groove of a TATA element

1993 • 1,039 citations

Five intermediate complexes in transcription initiation by RNA polymerase II

1989 • 1,033 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

TBP, a universal eukaryotic transcription factor?

1993 • 642 citations

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

1990 • 620 citations

Molecular and biochemical characterization of the human trk proto-oncogene.

1989 • 600 citations

Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators

1993 • 589 citations

The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity.

1989 • 572 citations

c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins.

1991 • 543 citations

Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences

1983 • 477 citations

Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation.

1986 • 468 citations

The jun and fos protein families are both required for cell cycle progression in fibroblasts.

1991 • 442 citations

A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity

1991 • 436 citations

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

1993 • 418 citations

Crystal structure of TFIID TATA-box binding protein

1992 • 410 citations

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.

1991 • 381 citations

Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor

1991 • 381 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

Binding of general transcription factor TFIIB to an acidic activating region

1991 • 377 citations

Reduced binding of TFIID to transcriptionally compromised mutants of VP16

1991 • 362 citations

jun:Oncogene and Transcription Factor

1990 • 337 citations

[75] Assay of transforming activity of tumor virus DNA

1980 • 331 citations

Family of proteins that interact with TFIID and regulate promoter activity

1991 • 319 citations

The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.

1993 • 317 citations

Eukaryotic activators function during multiple steps of preinitiation complex assembly

1993 • 311 citations

Expression of different Jun and Fos proteins during the G0-to-G1 transition in mouse fibroblasts: in vitro and in vivo associations.

1991 • 309 citations

Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells.

1988 • 266 citations

Diverse transcriptional functions of the multisubunit eukaryotic TFIID complex.

1992 • 265 citations

Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex.

1990 • 255 citations

The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction.

1991 • 249 citations

The p53 Activation Domain Binds the TATA Box-Binding Polypeptide in Holo-TFIID, and a Neighboring p53 Domain Inhibits Transcription

1993 • 246 citations

Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID.

1991 • 242 citations

Existence of different Fos/Jun complexes during the G0-to-G1 transition and during exponential growth in mouse fibroblasts: differential role of Fos proteins.

1992 • 198 citations

Difference in transcriptional regulatory function between c-Fos and Fra-2

1991 • 194 citations

Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-κB

1993 • 168 citations

Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif.

1993 • 162 citations

TFIID can be rate limiting in vivo for TATA-containing, but not TATA-lacking, RNA polymerase II promoters.

1992 • 151 citations

An alternative spliced form of FosB is a negative regulator of transcriptional activation and transformation by Fos proteins.

1991 • 150 citations

Advances in RNA polymerase II transcription

1992 • 149 citations

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein.

1993 • 146 citations

Alternative splicing of fosB transcripts results in differentially expressed mRNAs encoding functionally antagonistic proteins.

1991 • 145 citations

The mammalian TFIID protein is present in two functionally distinct complexes.

1991 • 142 citations

The retinoblastoma protein binds E2F residues required for activation in vivo and TBP bindingin vitro

1993 • 131 citations

Molecular and Biochemical Characterization of the Human trk Proto-Oncogene

1989 • 124 citations

Neoplastic transformation by the human gene N-myc.

1987 • 124 citations

Conserved motifs in Fos and Jun define a new class of activation domain.

1992 • 120 citations

Functional and biochemical interaction of the HTLV-I Tax1 transactivator with TBP.

1993 • 119 citations

Encounters with Fos and Jun on the road to AP-1.

1990 • 107 citations

Both products of the fosB gene, FosB and its short form, FosB/SF, are transcriptional activators in fibroblasts.

1991 • 98 citations

Transcription Factor IID Mutants Defective for Interaction with Transcription Factor IIA

1992 • 95 citations

Factors (TAFs) required for activated transcription interact with TATA box-binding protein conserved core domain.

1993 • 89 citations

Growth factor-responsive genes in fibroblasts.

1990 • 87 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Role of Transcription Factors IIA, IID, and IIB during Formation of a Transcription-Competent Complex

1990 • 87 citations

Transformation by Fos proteins requires a C-terminal transactivation domain.

1993 • 82 citations

Different TBP-associated factors are required for mediating the stimulation of transcriptionin vitroby the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor

1993 • 81 citations

Functional interaction of adenovirus E1A with holo-TFIID.

1993 • 79 citations

Structure and mapping of thefosB gene. FosB downregulates the activity of thefosB promotero

1992 • 71 citations

Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein (TFIID tau).

1992 • 64 citations

Microinjection of fos-Specific Antibodies Blocks DNA Synthesis in Fibroblast Cells

1988 • 52 citations

Transformation by FosB requires a trans-activation domain missing in FosB2 that can be substituted by heterologous activation domains.

1992 • 41 citations

The basic RNA polymerase II transcriptional machinery.

1992 • 30 citations

Neoplastic Transformation by the Human Gene N-myc

1987 • 27 citations

Constitutive expression of FosB and its short form, FosB/SF, induces malignant cell transformation in rat-1A cells.

1991 • 27 citations

Transformation by Fos Proteins Requires a C-Terminal Transactivation Domain

1993 • 18 citations

Multiple regions of v-Fos protein involved in the activation of AP1-dependent transcription: is trans-activation crucial for transformation?

1991 • 13 citations