Difference in transcriptional regulatory function between c-Fos and Fra-2

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA.

1988 • 897 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

A gene activated by growth factors is related to the oncogene v-jun.

1988 • 771 citations

Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun

1989 • 698 citations

Fos-Associated Protein p39 Is the Product of the jun Proto-Oncogene

1988 • 643 citations

Parallel Association of Fos and Jun Leucine Zippers Juxtaposes DNA Binding Domains

1989 • 607 citations

c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene

1984 • 601 citations

The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity.

1989 • 572 citations

Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini

1983 • 532 citations

The Fos Complex and Fos-Related Antigens Recognize Sequence Elements That Co ntain AP-1 Binding Sites

1988 • 532 citations

fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen.

1988 • 518 citations

Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro.

1988 • 511 citations

Characterization of junD: a new member of the jun proto-oncogene family.

1989 • 492 citations

jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun

1989 • 488 citations

jun-D: a third member of the jun gene family.

1989 • 469 citations

A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity

1991 • 436 citations

The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.

1989 • 318 citations

Isolation and characterization of fra-2, an additional member of the fos gene family.

1990 • 274 citations

Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein.

1985 • 249 citations

Interferon-β gene regulation: Tandemly repeated sequences of a synthetic 6 bp oligomer function as a virus-inducible enhancer

1987 • 233 citations

Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation.

1990 • 168 citations

fra-1: a Serum-Inducible, Cellular Immediate-Early Gene That Encodes a Fos-Related Antigen

1988 • 115 citations

Fos and jun cooperate in transcriptional regulation via heterologous activation domains.

1990 • 82 citations

Both Jun and Fos contribute to transcription activation by the heterodimer.

1990 • 81 citations

Viral and Cellular fos Proteins Are Complexed with a 39,000-Dalton Cellular Protein

1985 • 58 citations

High‐level Expression of Human c‐jun Gene Causes Cellular Transformation of Chicken Embryo Fibroblasts

1991 • 35 citations

Constitutive expression of c-fos antisense RNA blocks c-fos gene induction by interferon and by phorbol ester and reduces c-myc expression in F9 embryonal carcinoma cells.

1988 • 27 citations

Transforming potential and growth stimulating activity of the v-fos and c-fos genes carried by avian retrovirus vectors.

1988 • 25 citations

Fos and Jun Cooperate in Transcriptional Regulation via Heterologous Activation Domains

1990 • 21 citations

Identification of a small region of the v-fos gene product that is sufficient for transforming potential and growth-stimulating activity.

1989 • 20 citations

Transcription of -2 mRNA and phosphorylation of Fra-2 protein are stimulated by serum

1991 • 17 citations