Mechanism of Action of Novel Marine Neurotoxins on Ion Channels

Neurotoxins that Act on Voltage-Sensitive Sodium Channels in Excitable Membranes

1980 • 1,236 citations

Chemicals as tools in the study of excitable membranes.

1974 • 918 citations

Peptide Neurotoxins from Fish-Hunting Cone Snails

1985 • 742 citations

Poisonous and venomous marine animals of the world

1988 • 558 citations

Conus geographus toxins that discriminate between neuronal and muscle sodium channels.

1985 • 402 citations

A venom peptide with a novel presynaptic blocking action

1984 • 394 citations

Brevetoxins, unique activators of voltage-sensitive sodium channels, bind to specific sites in rat brain synaptosomes.

1986 • 313 citations

Ciguatoxin: Isolation and Chemical Nature

1967 • 286 citations

Ciguatoxin is a novel type of Na+ channel toxin.

1984 • 245 citations

Peptide toxins from Conus geographus venom.

1981 • 238 citations

An Integrated view of the Molecular Toxinology of Sodium Channel Gating in Excitable Cells

1987 • 221 citations

Origins of ciguatera fish poisoning: a new dinoflagellate, Gambierdiscus toxicus Adachi and Fukuyo, definitively involved as a causal agent

1980 • 212 citations

Isolation and structure of a peptide toxin from the marine snail Conus magus

1982 • 194 citations

Sea anemone toxin and scorpion toxin share a common receptor site associated with the action potential sodium ionophore.

1978 • 187 citations

Sea anemone toxin:a tool to study molecular mechanisms of nerve conduction and excitation-secretion coupling.

1976 • 184 citations

Decreased rate of sodium conductance inactivation in the node of Ranvier induced by a polypeptide toxin from sea anemone

1976 • 171 citations

Gymnodinium Brevis Sp. Nov., A Cause of Discolored Water and Animal Mortality in the Gulf of Mexico

1948 • 163 citations

Marine Food-Borne Dinoflagellate Toxins

1983 • 150 citations

Ciguatera Fish Poisoning

1982 • 146 citations

Conductance of the sodium channel in myelinated nerve fibres with modified sodium inactivation.

1976 • 133 citations

Ca2+ channel activating function of maitotoxin, the most potent marine toxin known, in clonal rat pheochromocytoma cells.

1983 • 131 citations

Toxicological evaluation of palytoxin in several animal species

1974 • 121 citations

Depolarizing action of a red-tide dinoflagellate brevetoxin on axonal membranes.

1984 • 118 citations

Ouabain inhibits the increase due to palytoxin of cation permeability of erythrocytes

1982 • 109 citations

Binding of sea anemone toxin to receptor sites associated with gating system of sodium channel in synaptic nerve endings in vitro.

1980 • 95 citations

Contractile response of the rabbit aorta to maitotoxin, the most potent marine toxin.

1983 • 90 citations

PRELIMINARY STUDIES ON THE VENOM OF THE MARINE SNAIL CONUS*

1960 • 89 citations

A Pharmacological Approach to the Structure of Sodium Channels in Myelinated Axons

1979 • 89 citations

Structure-function relationships of sea anemone toxin II from Anemonia sulcata.

1981 • 84 citations

Isochannels and Blocking Modes of Voltage‐Dependent Sodium Channels^a

1986 • 62 citations

Recent progress in marine toxin research

1982 • 61 citations

Characterization of the neurotoxic constituents of Conus geographus (L) venom

1977 • 58 citations

The mode of contractile action of palytoxin on vascular smooth muscle

1977 • 58 citations

Effect of palytoxin on membrane and potential and current of frog myelinated fibers.

1977 • 54 citations

Excitatory effect of the most potent marine toxin, maitotoxin, on the guinea-pig vas deferens.

1983 • 53 citations

Conus Venoms: A Rich Source of Neuroactive Peptides

1985 • 51 citations

A toxin from the venom of the marine snail Conus geographus which acts on the vertebrate central nervous system

1981 • 48 citations

Mechanism of the excitatory action of palytoxin and N-acetylpalytoxin in the isolated guinea-pig vas deferens.

1980 • 46 citations

Peptides isolated from the venom of Conus geographus block neuromuscular transmission

1981 • 45 citations

Palytoxin isolated from marine coelenterates. The inhibitory action on (Na,K)-ATPase.

1983 • 44 citations

Marine Pharmacology: Bioactive Molecules from the Sea

1986 • 41 citations

Cardiotoxic effects of maitotoxin, a principal toxin of seafood poisoning, on guinea pig and rat cardiac muscle.

1986 • 37 citations

Ciguatera Poisoning: Clinical and Immunological Aspects

1986 • 37 citations

Palytoxin binds to and inhibits kidney and erythrocyte Na+, K+-ATPase

1984 • 37 citations

Actions of Ptychodiscus brevis toxins on nerve and muscle membranes

1985 • 35 citations

Biological significance of peptides from Anemonia sulcata.

1983 • 28 citations

Sea anemone toxins: tools in the study of excitable membranes.

1979 • 28 citations

The effect of anthopleurin-A on crayfish giant axon.

1979 • 26 citations

A polypeptide toxin from the coral Goniopora

1986 • 21 citations

Marine ecology ? some chemical aspects

1982 • 21 citations

SCREENING OF TOXIC CORALS AND ISOLATION OF A TOXIC POLYPEPTIDE FROM GONIOPORA SPP

1973 • 17 citations

Structure and Biosynthesis of Neuronal Sodium Channels

1986 • 16 citations

Ion Permeation in Cell Membranes

1986 • 12 citations

(Na+ + K+)ATPase inhibition by PALYTHOA extracts

1977 • 9 citations

Excitatory and inhibitory effects of a myotoxin from Conus magus venom on the mouse diaphragm, the guinea-pig atria, taenia caeci, ileum and vas deferens

1982 • 9 citations

Preparation and properties of fluorescence labeled neuro- and cardiotoxin II from the sea anemone (Anemonia sulcata)

1983 • 8 citations

Mode of Action of Ciguatera Toxins

1984 • 7 citations

Deleted Work

1955 • 0 citations