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Identification of the site of interaction of the dihydropyridine channel blockers nitrendipine and azidopine with the calcium-channel alpha 1 subunit.

Data up to Jan 2025

Published1991
Citations112
References37

Total Citations Per Year

Abstract

References (37)

Primary structure of the receptor for calcium channel blockers from skeletal muscle

1987 • 1,359 citations

Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists

1984 • 1,292 citations

Classes of Calcium Channels in Vertebrate Cells

1989 • 1,082 citations

Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

1989 • 922 citations

Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.

1984 • 834 citations

Restoration of excitation—contraction coupling and slow calcium current in dysgenic muscle by dihydropyridine receptor complementary DNA

1988 • 803 citations

Sequence and Expression of mRNAs Encoding the α 1 and α 2 Subunits of a DHP-Sensitive Calcium Channel

1988 • 579 citations

Subunit structure of dihydropyridine-sensitive calcium channels from skeletal muscle.

1987 • 468 citations

Regulation of Cardiac L-Type Calcium Current by Phosphorylation and G Proteins

1990 • 359 citations

Dihydropyridine derivatives prolong the open state of Ca channels in cultured cardiac cells.

1984 • 323 citations

Amino acids of the Torpedo marmorata acetylcholine receptor .alpha. subunit labeled by a photoaffinity ligand for the acetylcholine binding site

1988 • 314 citations

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine.

1986 • 296 citations

Ca2+ channel ligands: Structure‐function relationships of the 1,4‐dihydropyridines

1989 • 252 citations

Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung

1990 • 240 citations

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: [3H]chlorpromazine labels homologous residues in the .beta. and .delta. chains

1987 • 228 citations

Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists.

1983 • 219 citations

[42] Assay for calcium channels

1985 • 191 citations

Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes.

1986 • 190 citations

The 1,4-dihydropyridine receptor associated with the skeletal muscle voltage-dependent Ca2+ channel. Purification and subunit composition.

1985 • 163 citations

Identification of a novel 1,4-dihydropyridine- and phenylalkylamine-binding polypeptide in calcium channel preparations.

1987 • 150 citations

Biochemical and ultrastructural characterization of the 1,4-dihydropyridine receptor from rabbit skeletal muscle. Evidence for a 52,000 Da subunit.

1988 • 120 citations

Comparison of location and binding for the positively charged 1,4-dihydropyridine calcium channel antagonist amlodipine with uncharged drugs of this class in cardiac membranes.

1989 • 117 citations

The 165‐KDa peptide of the purified skeletal muscle dihydropyridine receptor contains the known regulatory sites of the calcium channel

1987 • 117 citations

Site of covalent attachment of alpha-scorpion toxin derivatives in domain I of the sodium channel alpha subunit.

1988 • 111 citations

Purification of a functional receptor for calcium‐channel blockers from rabbit skeletal‐muscle microsomes

1986 • 107 citations

The reaction site of a non-competitive antagonist in the delta-subunit of the nicotinic acetylcholine receptor.

1986 • 104 citations

Photoaffinity labelling of Ca2+ channels with [3H]azidopine

1984 • 90 citations

Mapping of the nucleotide-binding sites in the ADP/ATP carrier of beef heart mitochondria by photolabeling with 2-azido[.alpha.-32P]adenosine diphosphate

1988 • 85 citations

Cardiac troponin I, isolated from‐bovine heart, contains two adjacent phosphoserines

1988 • 73 citations

Effects of metal cations and calmodulin antagonists on [3H] nitrendipine binding in smooth and cardiac muscle.

1984 • 71 citations

Direct photoaffinity labeling of the high affinity nitrendipine-binding site in subcellular membrane fractions isolated from canine myocardium.

1984 • 64 citations

Characterization of the binding sites for nimodipine and (−)‐desmethoxyverapamil in bovine cardiac sarcolemma

1985 • 53 citations

The Molecular Structure and Regulation of Muscular Calcium Channels

1990 • 35 citations

High and low affinity states of the dihydropyridine and phenylakylamine receptors on the cardiac calcium channel and their interconversion by divalent cations

1985 • 34 citations

The interactions of 1,4-dihydropyridines bearing a 2-(2-aminoethylthio)methyl substituent at voltage-dependent Ca+ channels of smooth muscle, cardiac muscle and neuronal tissues

1990 • 14 citations

Photoaffinity Labeling with Dihydropyridine Derivatives of Crude Membranes from Rat Skeletal, Cardiac, Ileal, and Uterine Muscles and Whole Brain

1989 • 10 citations

[Studies on the analysis of nifedipine considering in particular transformation products formed by light exposition (author's transl)].

1978 • 10 citations

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