Characterization of the binding sites for nimodipine and (−)‐desmethoxyverapamil in bovine cardiac sarcolemma

Specific Pharmacology of Calcium in Myocardium, Cardiac Pacemakers, and Vascular Smooth Muscle

1977 • 1,745 citations

Calcium channel modulation by neurotransmitters, enzymes and drugs

1983 • 1,267 citations

Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.

1984 • 834 citations

New developments in calcium ion channel antagonists

1983 • 525 citations

Injection of subunits of cyclic AMP-dependent protein kinase into cardiac myocytes modulates Ca2+ current

1982 • 421 citations

[3H]nitrendipine receptors in skeletal muscle.

1983 • 381 citations

Calcium channels: direct identification with radioligand binding studies

1982 • 302 citations

Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.

1983 • 292 citations

Drug and Neurotransmitter Receptors in the Brain

1984 • 274 citations

[3H]nitrendipine-labeled calcium channels discriminate inorganic calcium agonists and antagonists.

1982 • 265 citations

Inotropic and electrophysiological actions of verapamil and D 600 in mammalian myocardium

1975 • 258 citations

Does the organic calcium channel blocker D600 act from inside or outside on the cardiac cell membrane?

1982 • 254 citations

Sites of action of Ca2+ channel inhibitors

1983 • 224 citations

A unitary mechanism of calcium antagonist drug action.

1983 • 214 citations

The interaction of [3H]nitrendipine with receptors for calcium antagonists in the cerebral cortex and heart of rats

1982 • 186 citations

Cellular Action of Calcium Channel Blocking Drugs

1984 • 159 citations

Specific binding of [3H]nitrendipine to membranes from coronary arteries and heart in relation to pharmacological effects. Paradoxical stimulation by diltiazem

1982 • 158 citations

Dihydropyridine receptor in rat brain labeled with [3H]nimodipine.

1983 • 153 citations

Injection of catalytic subunit of cAMP-dependent protein kinase into isolated cardiac myocytes

1983 • 149 citations

Ion Channels in Cardiac Cell Membranes

1984 • 148 citations

Evidence for multiple receptor sites within the putative calcium channel

1982 • 134 citations

Specific calcium antagonist binding sites in brain

1982 • 119 citations

Calcium channel block and recovery from block in mammalian ventricular muscle treated with organic channel inhibitors

1982 • 112 citations

Graphical analysis of ligand-binding systems: Evaluation by Monte Carlo studies

1980 • 104 citations

Identification of putative calcium channels in skeletal muscle microsomes

1982 • 102 citations

Diltiazem enhancement of [3H]nitrendipine binding to calcium channel associated drug receptor sites in rat brain synaptosomes

1982 • 97 citations

Temperature‐dependent regulation of d‐cis‐[³H]diltiazem binding to Ca²⁺ channels by 1,4‐dihydropyridine channel agonists and antagonists

1983 • 96 citations

Characteristics of the binding of [3H]nitrendipine to rabbit ventricular membranes: modification by other Ca++ channel antagonists and by the Ca++ channel agonist Bay K 8644.

1984 • 87 citations

Tissue heterogeneity of calcium channel antagonist binding sites labeled by [3H]nitrendipine.

1984 • 84 citations

(?)-3H-desmethoxyverapamil labelling of putative calcium channels in brain: autoradiographic distribution and allosteric coupling to 1,4-dihydropyridine and diltiazem binding sites

1984 • 84 citations

Properties of receptors for the Ca²⁺‐channel blocker verapamil in transverse‐tubule membranes of skeletal muscle

1984 • 81 citations

Characterization of [3H]nifedipine binding sites in rabbit myocardium

1982 • 75 citations

Chronotropic, inotropic, and vasodilator actions of diltiazem, nifedipine, and verapamil. A comparative study of physiological responses and membrane receptor activity.

1983 • 74 citations

[3H] verapamil binding sites in skeletal muscle tranverse tubule membranes

1984 • 64 citations

Solubilization of the nitrendipine receptor from skeletal muscle transverse tubule membranes Interactions with specific inhibitors of the voltage‐dependent Ca²⁺ channel

1984 • 64 citations

Target size analysis and molecular properties of Ca²⁺ channels labelled with [³H]verapamil

1984 • 62 citations

Effects of Ca Antagonists on Ca Fluxes in Resistance Vessels

1982 • 61 citations

(—)‐[³H]Desmethoxyverapamil, a novel Ca²⁺ channel probe

1984 • 60 citations

Relationship of binding of a calcium channel blocker to inhibition of contraction in intact cultured embryonic chick ventricular cells.

1983 • 56 citations

Effects of dihydropyridine calcium channel modulators in the heart: Pharmacological and radioligand binding correlations

1984 • 53 citations

Adenosine uptake sites in dog heart and brain; interaction with calcium antagonists

1984 • 52 citations

Characterization of verapamil binding sites in cardiac membrane vesicles.

1984 • 51 citations

Diltiazem potentiates the negative inotropic action of nimodipine in heart

1983 • 48 citations

Temperature-dependent modulation of [3H]nitrendipine binding by the calcium channel antagonists verapamil and diltiazem in rat brain synaptosomes.

1984 • 46 citations

[3H]verapamil binding sites in brain and skeletal muscle: Regulation by calcium

1983 • 45 citations

Nucleoside transport in human erythrocytes. Apparent molecular weight of the nitrobenzylthioinosine-binding complex estimated by radiation-inactivation analysis

1980 • 43 citations

Phosphorylation of purified bovine cardiac sarcolemma and potassium‐stimulated calcium uptake

1983 • 32 citations

Solubilization and affinity labeling of a dihydropyridine binding site from skeletal muscle: Effects of temperature and diltiazem on [3H]dihydropyridine binding to transverse tubules

1984 • 27 citations

Calcium channel modulation: evidence that the ability to inhibit or promote calciuminflux resides in the same dihydropyridine molecule

1984 • 1 citations

Identification, solubilization and partially purification of binding sites for calcium entry blockers in bovine cardiac muscle

1984 • 1 citations